Etiology, risk factors and sex differences in ischemic stroke in the ludwigshafen stroke study, a population-based stroke registry

Cerebrovascular Diseases

Volumn 33, Issue 1, 2012, Pages 69-75

  Palm, F ^a   Urbanek, C ^a   Wolf, J ^a   Buggle, F ^a   Kleemann, T ^a   Hennerici, M G ^c   Inselmann, G ^b   Hagar, M ^a   Safer, A ^d   Becher, H ^d   Grau, A J ^a  

^a KLINIKUM LUDWIGSHAFEN   (Germany)

^b Klinikum Ludwigshafen ^*  (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Gender; Ischemic stroke; Population based stroke registry; Stroke etiology; Stroke mortality

Indexed keywords

ADULT; AGED; AORTA VALVE STENOSIS; ARTERY OCCLUSION; ARTICLE; ATHEROSCLEROSIS; BACTERIAL ENDOCARDITIS; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; DIABETES MELLITUS; EMBOLISM; FEMALE; GROUPS BY AGE; HEART ATRIUM FIBRILLATION; HEART ATRIUM MYXOMA; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MALE; MITRAL VALVE STENOSIS; PATENT FORAMEN OVALE; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEX DIFFERENCE; SMOKING; SURVIVAL; TRANSIENT ISCHEMIC ATTACK;

ADULT; AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; CHI-SQUARE DISTRIBUTION; CORONARY ARTERY DISEASE; EMBOLISM; FEMALE; GERMANY; HUMANS; INCIDENCE; ISCHEMIC ATTACK, TRANSIENT; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; PERIPHERAL ARTERIAL DISEASE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; SEX FACTORS; STROKE;

EID: 82355172014     PISSN: 10159770     EISSN: 14219786     Source Type: Journal    
DOI: 10.1159/000333417     Document Type: Article

References (29)

1. Palm F, Urbanek C, Rose S, Buggle F, Bode B, Hennerici MG, Schmieder K, Inselmann G,Reiter R, Fleischer R, Piplack KO, Safer A, Becher H, Grau AJ: Stroke incidence and survival in Ludwigshafen am Rhein, Germany: the Ludwigshafen stroke study (LuSSt). Stroke 2010; 41: 1865-1870.
2. Appelros P, Stegmayr B, Terent A: Sex differences in stroke epidemiology: a systematic review. Stroke 2009; 40: 1082-1090.
3. Hatano S: Experience from a multicentre stroke register: a preliminary report. Bull World Health Organ 1976; 54: 541-553. (Pubitemid 8114220)
4. Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE 3rd: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. Toast. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993; 24: 35-41. (Pubitemid 23014379)
5. Touboul PJ, Elbaz A, Koller C, Lucas C, Adrai V, Chedru F, Amarenco P: Common carotid artery intima-media thickness and brain infarction: the Etude du Profil Génétique de l'Infarctus Cérébral (GENIC) casecontrol study. The GENIC Investigators. Circulation 2000; 102: 313-318. (Pubitemid 30457582)
6. Bousser MG, Amarenco P, Chamorro A, Fisher M, Ford I, Fox K, Hennerici MG, Mattle HP, Rothwell PM: Rationale and design of a randomized, double-blind, parallel-group study of terutroban 30 mg/day versus aspirin 100 mg/day in stroke patients: the prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) study. Cerebrovasc Dis 2009; 27: 509-518.
7. Ay H, Furie KL, Singhal A, Smith WS, Sorensen AG, Koroshetz WJ: An evidencebased causative classification system for acute ischemic stroke. Ann Neurol 2005; 58: 688-697 (Pubitemid 41552544)
8. The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med 1997; 157: 2413-2446.
9. Balkau B: The decode study. Diabetes epidemiology: collaborative analysis of diagnostic criteria in Europe. Diabetes Metab 2000; 26: 282-286.
10. Bonita R, Broad JB, Anderson NE, Beaglehole R: Approaches to the problems of measuring the incidence of stroke: The Auckland Stroke Study, 1991-1992. Int J Epidemiol 1995; 24: 535-542.
11. Feigin VL, Carter K: Editorial comment -stroke incidence studies one step closer to the elusive gold standard? Stroke 2004; 35: 2045-2047. (Pubitemid 39129557)
12. Sudlow CL, Warlow CP: Comparing stroke incidence worldwide: what makes studies comparable? Stroke 1996; 27: 550-558.
13. Doll R, Cook P: Summarizing indices for comparison of cancer incidence data. Int J Cancer 1967; 2: 269-279.
14. Förster A, Gass A, Kern R, Wolf ME, Ottomeyer C, Zohsel K, Hennerici M, Szabo K: Gender differences in acute ischemic stroke: etiology, stroke patterns and response to thrombolysis. Stroke 2009; 40: 2428-2432.
15. Andersen KK, Andersen ZJ, Olsen TS: Ageand gender-specific prevalence of cardiovascular risk factors in 40,102 patients with first-ever ischemic stroke: a Nationwide Danish Study. Stroke 2010; 41: 2768-2774.
16. Arboix A, Oliveres M, Garcia-Eroles L, Maragall C, Massons J, Targa C: Acute cerebrovascular disease in women. Eur Neurol 2001; 45: 199-205. (Pubitemid 32521036)
17. Mosca L, Manson JE, Sutherland SE, Langer RD, Manolio T, Barrett-Connor E: Cardiovascular disease in women: a statement for healthcare professionals from the American Heart Association. Writing Group. Circulation 1997; 96: 2468-2482.
18. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O'Donnell C, Roger V, Sorlie P, Steinberger J, Thom T, Wilson M, Hong Y: Heart disease and stroke statistics -2008 update: a report from the American Heart Association StatisticsCommittee and Stroke Statistics Subcommittee. Circulation 2008; 117:e25-e146.
19. Grau AJ, Weimar C, Buggle F, Heinrich A, Goertler M, Neumaier S, Glahn J, Brandt T, Hacke W, Diener HC: Risk factors, outcome, and treatment in subtypes of ischemic stroke: The German Stroke Data Bank. Stroke 2001; 32: 2559-2566. (Pubitemid 33055306)
20. Hannon N, Sheehan O, Kelly L, Marnane M, Merwick A, Moore A, Kyne L, Duggan J, Moroney J, McCormack PM, Daly L, Fitz-Simon N, Harris D, Horgan G, Williams EB, Furie KL, Kelly PJ: Stroke associated with atrial fibrillation -incidence and early outcomes in the north Dublin population stroke study. Cerebrovasc Dis 2010; 29: 43-49.
21. Marnane M, Duggan CA, Sheehan OC, Merwick A, Hannon N, Curtin D, Harris D, Williams EB, Horgan G, Kyne L, McCormack PM, Duggan J, Moore A, Crispino-O'Connell G, Kelly PJ: Stroke subtype classification to mechanism-specific and undetermined categories by TOAST, A-S-C-O, and causative classification system: direct comparison in the North Dublin population stroke study. Stroke 2010; 41: 1579-1586.
22. Kolominsky-Rabas PL, Weber M, Gefeller O, Neundoerfer B, Heuschmann PU: Epidemiology of ischemic stroke subtypes according to toast criteria: incidence, recurrence, and long-term survival in ischemic stroke subtypes: a population-based study. Stroke 2001; 32: 2735-2740. (Pubitemid 33134456)
23. Holroyd-Leduc JM, Kapral MK, Austin PC, Tu JV: Sex differences and similarities in the management and outcome of stroke patients. Stroke 2000; 31: 1833-1837. (Pubitemid 30620459)
24. Roquer J, Campello AR, Gomis M: Sex differences in first-ever acute stroke. Stroke 2003; 34: 1581-1585. (Pubitemid 36842605)
25. Amarenco P: Underlying pathology of stroke of unknown cause (cryptogenic stroke). Cerebrovasc Dis 2009; 27(suppl 1):97-103.
26. Arboix A, Cendros V, Besa M, Garcia-Eroles L, Oliveres M, Targa C, Balcells M, Comes E, Massons J: Trends in risk factors, stroke subtypes and outcome. Nineteen-year data from the Sagrat Cor Hospital of Barcelona stroke registry. Cerebrovasc Dis 2008; 26: 509-516.
27. Petty GW, Brown RD Jr, Whisnant JP, Sicks JD, O'Fallon WM, Wiebers DO: Ischemic stroke subtypes: a population-based study of incidence and risk factors. Stroke 1999; 30: 2513-2516.
28. Sharma JC, Fletcher S, Vassallo M: Characteristics and mortality of acute stroke patients: are there any gender differences? J Gend Specif Med 2002; 5: 24-27. (Pubitemid 34662255)
29. Petrea RE, Beiser AS, Seshadri S, Kelly-Hayes M, Kase CS, Wolf PA: Gender differences in stroke incidence and poststroke disability in the Framingham heart study. Stroke 2009; 40: 1032-1037.