Synthesis and cross coupling of a highly substituted 2-pyridylboronate: Application to the large scale synthesis of a mineralocorticoid antagonist

Tetrahedron Letters

Volumn 52, Issue 52, 2011, Pages 7025-7029

  Boos, Charles ^a   Bowles, Daniel M ^a   Cai, Cuiman ^a   Casimiro Garcia, Agustin ^a   Chen, Xiangyang ^a   Hulford, Catherine A ^a   Jennings, Sandra M ^a   Jason Kiser, E ^a   Piotrowski, David W ^a   Sammons, Matthew ^a   Wade, Robert A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

2 Pyridylboronate; Large scale synthesis; Pyrazoline; Suzuki Miyaura coupling

Indexed keywords

BORONIC ACID DERIVATIVE; MINERALOCORTICOID ANTAGONIST; PYRAZOLINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION OPTIMIZATION; SUBSTITUTION REACTION; SUZUKI REACTION; SYNTHESIS;

EID: 82255191301     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.10.052     Document Type: Article

References (13)

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