Ortho-selectivity in the nucleophilic aromatic substitution (S NAr) reactions of 3-substituted, 2,6-dichloropyridines with alkali metal alkoxides

Tetrahedron Letters

Volumn 52, Issue 32, 2011, Pages 4172-4176

  Yap, Jeremy L ^a   Hom, Kellie ^a   Fletcher, Steven ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

2,6 Dichloro 3 nitropyridine; Coordination; Nucleophilic aromatic substitution (SNAr); Ortho; Regioselective

Indexed keywords

ALKALI METAL; CHLORINE DERIVATIVE; COUNTERION; HYDROGEN; LEWIS ACID; LITHIUM ION; OXIDE; PYRIDINE DERIVATIVE; SODIUM ION; SOLVENT;

ALKYLATION; ARTICLE; HYDROGEN BOND; NUCLEOPHILIC AROMATIC SUBSTITUTION REACTION; SOLVATION; SUBSTITUTION REACTION; SYNTHESIS; THERMODYNAMICS;

EID: 79960416574     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.06.007     Document Type: Article

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