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Volumn 12, Issue 11, 2011, Pages 8133-8145

C57Bl/KsJ-db/db-Apc min/+ mice exhibit an increased incidence of intestinal neoplasms

Author keywords

Animal model; C57BL 6J Apc min +; C57Bl KsJ db db; Colon carcinogenesis; Type 2 diabetes mellitus

Indexed keywords

APC PROTEIN; BETA CATENIN; CHOLESTEROL; GLUCOSE; INSULIN; INTERFERON REGULATORY FACTOR 1 RECEPTOR; RNA; SOMATOMEDIN B; SOMATOMEDIN C; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; IGF2 PROTEIN, MOUSE; INSULIN-LIKE GROWTH FACTOR-1, MOUSE; MESSENGER RNA;

EID: 82255180784     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12118133     Document Type: Article
Times cited : (13)

References (48)
  • 2
    • 0034331208 scopus 로고    scopus 로고
    • Body mass index and colon cancer mortality in a large prospective study
    • Murphy, T.K.; Calle, E.E.; Rodriguez, C.; Kahn, H.S.; Thun, M.J. Body mass index and colon cancer mortality in a large prospective study. Am. J. Epidemiol. 2000, 152, 847-854.
    • (2000) Am. J. Epidemiol , vol.152 , pp. 847-854
    • Murphy, T.K.1    Calle, E.E.2    Rodriguez, C.3    Kahn, H.S.4    Thun, M.J.5
  • 3
    • 54549094827 scopus 로고    scopus 로고
    • Obesity and type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence
    • LeRoith, D.; Novosyadlyy, R.; Gallagher, E.J.; Lann, D.; Vijayakumar, A.; Yakar, S. Obesity and type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence. Exp. Clin. Endocrinol. Diabetes 2008, 116, S4-S6.
    • (2008) Exp. Clin. Endocrinol. Diabetes , vol.116
    • Leroith, D.1    Novosyadlyy, R.2    Gallagher, E.J.3    Lann, D.4    Vijayakumar, A.5    Yakar, S.6
  • 4
    • 0037677202 scopus 로고    scopus 로고
    • Hyperinsulinaemia and hyperglycaemia: Possible risk factors of colorectal cancer among diabetic patients
    • Chang, C.K.; Ulrich, C.M. Hyperinsulinaemia and hyperglycaemia: Possible risk factors of colorectal cancer among diabetic patients. Diabetologia 2003, 46, 595-607.
    • (2003) Diabetologia , vol.46 , pp. 595-607
    • Chang, C.K.1    Ulrich, C.M.2
  • 5
    • 68149131125 scopus 로고    scopus 로고
    • Obesity related hyperinsulinaemia and hyperglycaemia and cancer development
    • Becker, S.; Dossus, L.; Kaaks, R. Obesity related hyperinsulinaemia and hyperglycaemia and cancer development. Arch. Physiol. Biochem. 2009, 115, 86-96.
    • (2009) Arch. Physiol Biochem , vol.115 , pp. 86-96
    • Becker, S.1    Dossus, L.2    Kaaks, R.3
  • 8
    • 77953619439 scopus 로고    scopus 로고
    • Insulin, insulin resistance, obesity, and cancer
    • Gallagher, E.J.; LeRoith, D. Insulin, insulin resistance, obesity, and cancer. Curr. Diabet. Rep. 2010, 10, 93-100.
    • (2010) Curr. Diabet. Rep , vol.10 , pp. 93-100
    • Gallagher, E.J.1    Leroith, D.2
  • 9
    • 33748703827 scopus 로고    scopus 로고
    • Obesity and cancer risk: The role of the insulin-IGF axis
    • Renehan, A.G.; Frystyk, J.; Flyvbjerg, A. Obesity and cancer risk: The role of the insulin-IGF axis. Trends Endocrinol. Metab. 2006, 17, 328-336.
    • (2006) Trends Endocrinol. Metab , vol.17 , pp. 328-336
    • Renehan, A.G.1    Frystyk, J.2    Flyvbjerg, A.3
  • 11
  • 12
    • 0037278448 scopus 로고    scopus 로고
    • Azoxymethane-induced beta-catenin-accumulated crypts in colonic mucosa of rodents as an intermediate biomarker for colon carcinogenesis
    • Hirose, Y.; Kuno, T.; Yamada, Y.; Sakata, K.; Katayama, M.; Yoshida, K.; Qiao, Z.; Hata, K.; Yoshimi, N.; Mori, H. Azoxymethane-induced beta-catenin-accumulated crypts in colonic mucosa of rodents as an intermediate biomarker for colon carcinogenesis. Carcinogenesis 2003, 24, 107-111.
    • (2003) Carcinogenesis , vol.24 , pp. 107-111
    • Hirose, Y.1    Kuno, T.2    Yamada, Y.3    Sakata, K.4    Katayama, M.5    Yoshida, K.6    Qiao, Z.7    Hata, K.8    Yoshimi, N.9    Mori, H.10
  • 14
    • 33845608136 scopus 로고    scopus 로고
    • Diet supplemented with citrus unshiu segment membrane suppresses chemically induced colonic preneoplastic lesions and fatty liver in male db/db mice
    • Suzuki, R.; Kohno, H.; Yasui, Y.; Hata, K.; Sugie, S.; Miyamoto, S.; Sugawara, K.; Sumida, T.; Hirose, Y.; Tanaka, T. Diet supplemented with citrus unshiu segment membrane suppresses chemically induced colonic preneoplastic lesions and fatty liver in male db/db mice. Int. J. Cancer 2007, 120, 252-258.
    • (2007) Int. J. Cancer , vol.120 , pp. 252-258
    • Suzuki, R.1    Kohno, H.2    Yasui, Y.3    Hata, K.4    Sugie, S.5    Miyamoto, S.6    Sugawara, K.7    Sumida, T.8    Hirose, Y.9    Tanaka, T.10
  • 15
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser, A.R.; Pitot, H.C.; Dove, W.F. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990, 247, 322-324.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 18
    • 27644468268 scopus 로고    scopus 로고
    • How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men
    • Corpet, D.E.; Pierre, F. How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men. Eur. J. Cancer 2005, 41, 1911-1922.
    • (2005) Eur. J. Cancer , vol.41 , pp. 1911-1922
    • Corpet, D.E.1    Pierre, F.2
  • 20
    • 0030299879 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention
    • DuBois, R.N.; Giardiello, F.M.; Smalley, W.E. Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention. Gastroenterol. Clin. North Am. 1996, 25, 773-791.
    • (1996) Gastroenterol. Clin. North Am , vol.25 , pp. 773-791
    • Dubois, R.N.1    Giardiello, F.M.2    Smalley, W.E.3
  • 23
    • 0345099451 scopus 로고    scopus 로고
    • Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPAR gamma ligand
    • Niho, N.; Takahashi, M.; Shoji, Y.; Takeuchi, Y.; Matsubara, S.; Sugimura, T.; Wakabayashi, K. Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPAR gamma ligand. Cancer Sci. 2003, 94, 960-964.
    • (2003) Cancer Sci , vol.94 , pp. 960-964
    • Niho, N.1    Takahashi, M.2    Shoji, Y.3    Takeuchi, Y.4    Matsubara, S.5    Sugimura, T.6    Wakabayashi, K.7
  • 25
    • 0027327503 scopus 로고
    • Insulinlike growth factors and binding proteins in colon cancer
    • Singh, P.; Rubin, N. Insulinlike growth factors and binding proteins in colon cancer. Gastroenterology 1993, 105, 1218-1237.
    • (1993) Gastroenterology , vol.105 , pp. 1218-1237
    • Singh, P.1    Rubin, N.2
  • 26
    • 34047174592 scopus 로고    scopus 로고
    • The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer
    • Belfiore, A. The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer. Curr. Pharm. Des. 2007, 13, 671-686.
    • (2007) Curr. Pharm. Des , vol.13 , pp. 671-686
    • Belfiore, A.1
  • 28
    • 65649099102 scopus 로고    scopus 로고
    • Supplementation with branched-chain amino acids inhibits azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice
    • Shimizu, M.; Shirakami, Y.; Iwasa, J.; Shiraki, M.; Yasuda, Y.; Hata, K.; Hirose, Y.; Tsurumi, H.; Tanaka, T.; Moriwaki, H. Supplementation with branched-chain amino acids inhibits azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice. Clin. Cancer Res. 2009, 15, 3068-3075.
    • (2009) Clin. Cancer Res , vol.15 , pp. 3068-3075
    • Shimizu, M.1    Shirakami, Y.2    Iwasa, J.3    Shiraki, M.4    Yasuda, Y.5    Hata, K.6    Hirose, Y.7    Tsurumi, H.8    Tanaka, T.9    Moriwaki, H.10
  • 29
    • 0035951686 scopus 로고    scopus 로고
    • Susceptibility of lean and obese Zucker rats to tumorigenesis induced by N-methyl-N-nitrosourea
    • Lee, W.M.; Lu, S.; Medline, A.; Archer, M.C. Susceptibility of lean and obese Zucker rats to tumorigenesis induced by N-methyl-N-nitrosourea. Cancer Lett. 2001, 162, 155-160.
    • (2001) Cancer Lett , vol.162 , pp. 155-160
    • Lee, W.M.1    Lu, S.2    Medline, A.3    Archer, M.C.4
  • 31
    • 47349113216 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus as risk factor for colorectal cancer
    • Berster, J.M.; Goke, B. Type 2 diabetes mellitus as risk factor for colorectal cancer. Arch. Physiol. Biochem. 2008, 114, 84-98.
    • (2008) Arch. Physiol. Biochem , vol.114 , pp. 84-98
    • Berster, J.M.1    Goke, B.2
  • 32
    • 79955932544 scopus 로고    scopus 로고
    • Is diabetes a causal agent for colorectal cancer? Pathophysiological and molecular mechanisms
    • Giouleme, O.; Diamantidis, M.D.; Katsaros, M.G. Is diabetes a causal agent for colorectal cancer? Pathophysiological and molecular mechanisms. World J. Gastroenterol. 2011, 17, 444-448.
    • (2011) World J. Gastroenterol , vol.17 , pp. 444-448
    • Giouleme, O.1    Diamantidis, M.D.2    Katsaros, M.G.3
  • 33
    • 31544447185 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of colorectal cancer in the Singapore Chinese Health Study
    • Seow, A.; Yuan, J.M.; Koh, W.P.; Lee, H.P.; Yu, M.C. Diabetes mellitus and risk of colorectal cancer in the Singapore Chinese Health Study. J. Natl. Cancer Inst. 2006, 98, 135-138.
    • (2006) J. Natl. Cancer Inst , vol.98 , pp. 135-138
    • Seow, A.1    Yuan, J.M.2    Koh, W.P.3    Lee, H.P.4    Yu, M.C.5
  • 34
    • 0035160628 scopus 로고    scopus 로고
    • Insulin, insulin-like growth factors and colon cancer: A review of the evidence
    • Giovannucci, E. Insulin, insulin-like growth factors and colon cancer: A review of the evidence. J. Nutr. 2001, 131, 3109S-3120S.
    • (2001) J. Nutr , vol.131
    • Giovannucci, E.1
  • 35
    • 77953199006 scopus 로고    scopus 로고
    • Insulin resistance and cancer: Epidemiological evidence
    • Tsugane, S.; Inoue, M. Insulin resistance and cancer: Epidemiological evidence. Cancer Sci. 2010, 101, 1073-1079.
    • (2010) Cancer Sci , vol.101 , pp. 1073-1079
    • Tsugane, S.1    Inoue, M.2
  • 37
    • 77956230328 scopus 로고    scopus 로고
    • Defining the pathway to insulin-like growth factor system targeting in cancer
    • Rosenzweig, S.A.; Atreya, H.S. Defining the pathway to insulin-like growth factor system targeting in cancer. Biochem. Pharmacol. 2010, 80, 1115-1124.
    • (2010) Biochem. Pharmacol , vol.80 , pp. 1115-1124
    • Rosenzweig, S.A.1    Atreya, H.S.2
  • 38
    • 0030778154 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-1: Recent findings and new directions
    • Lee, P.D.; Giudice, L.C.; Conover, C.A.; Powell, D.R. Insulin-like growth factor binding protein-1: Recent findings and new directions. Proc. Soc. Exp. Biol. Med. 1997, 216, 319-357.
    • (1997) Proc. Soc. Exp. Biol. Med , vol.216 , pp. 319-357
    • Lee, P.D.1    Giudice, L.C.2    Conover, C.A.3    Powell, D.R.4
  • 40
    • 33645866760 scopus 로고    scopus 로고
    • Possible involvement of hyperlipidemia in increasing risk of colorectal tumor development in human familial adenomatous polyposis
    • Mutoh, M.; Akasu, T.; Takahashi, M.; Niho, N.; Yoshida, T.; Sugimura, T.; Wakabayashi, K. Possible involvement of hyperlipidemia in increasing risk of colorectal tumor development in human familial adenomatous polyposis. Jpn. J. Clin. Oncol. 2006, 36, 166-171.
    • (2006) Jpn. J. Clin. Oncol , vol.36 , pp. 166-171
    • Mutoh, M.1    Akasu, T.2    Takahashi, M.3    Niho, N.4    Yoshida, T.5    Sugimura, T.6    Wakabayashi, K.7
  • 42
    • 44949241791 scopus 로고    scopus 로고
    • Hyperglycemia and hypertriglyceridemia may associate with the adenoma-carcinoma transition in colorectal epithelial cells
    • Tabuchi, M.; Kitayama, J.; Nagawa, H. Hyperglycemia and hypertriglyceridemia may associate with the adenoma-carcinoma transition in colorectal epithelial cells. J. Gastroenterol. Hepatol. 2008, 23, 985-987.
    • (2008) J. Gastroenterol. Hepatol , vol.23 , pp. 985-987
    • Tabuchi, M.1    Kitayama, J.2    Nagawa, H.3
  • 44
    • 0141842617 scopus 로고    scopus 로고
    • Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands
    • Niho, N.; Takahashi, M.; Kitamura, T.; Shoji, Y.; Itoh, M.; Noda, T.; Sugimura, T.; Wakabayashi, K. Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands. Cancer Res. 2003, 63, 6090-6095.
    • (2003) Cancer Res , vol.63 , pp. 6090-6095
    • Niho, N.1    Takahashi, M.2    Kitamura, T.3    Shoji, Y.4    Itoh, M.5    Noda, T.6    Sugimura, T.7    Wakabayashi, K.8
  • 47
    • 14544306090 scopus 로고    scopus 로고
    • Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity in Min mice
    • Niho, N.; Mutoh, M.; Takahashi, M.; Tsutsumi, K.; Sugimura, T.; Wakabayashi, K. Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity in Min mice. Proc. Natl. Acad. Sci. USA 2005, 102, 2970-2974.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 2970-2974
    • Niho, N.1    Mutoh, M.2    Takahashi, M.3    Tsutsumi, K.4    Sugimura, T.5    Wakabayashi, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.