Allelic variations in superoxide dismutase-1 (SOD1) gene are associated with increased risk of diabetic nephropathy in type 1 diabetic subjects

Molecular Genetics and Metabolism

Volumn 104, Issue 4, 2011, Pages 654-660

  Mohammedi, Kamel ^a,b   Maimaitiming, Suliya ^a   Emery, Nathalie ^a,c   Bellili Muñoz, Naima ^a   Roussel, Ronan ^a,b,c   Fumeron, Frédéric ^a,c   Hadjadj, Samy ^a,d,e   Marre, Michel ^a,b,c   Velho, Gilberto ^a  

^a INSERM   (France)

^b BICHAT HOSPITAL   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d POITIERS UNIVERSITY HOSPITAL   (France)

^e UNIVERSITÉ DE POITIERS   (France)

Author keywords

Diabetic nephropathy; Genetic epidemiology; Oxidative stress; Population studies; Superoxide dismutase

Indexed keywords

ANTIHYPERTENSIVE AGENT; COPPER ZINC SUPEROXIDE DISMUTASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCINE; THREONINE;

ADULT; ALLELE; ANTIHYPERTENSIVE THERAPY; ARTICLE; BELGIUM; CAUCASIAN; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETIC NEPHROPATHY; DIABETIC PATIENT; DIABETIC RETINOPATHY; DISEASE SEVERITY; EUROPE; FEMALE; FOLLOW UP; FRANCE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC VARIABILITY; GLOMERULUS FILTRATION RATE; HAZARD RATIO; HUMAN; HYPERTENSION; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREVALENCE; PRIORITY JOURNAL; PROMOTER REGION; PROSPECTIVE STUDY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ALLELES; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GLOMERULAR FILTRATION RATE; HAPLOTYPES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PREVALENCE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS; SUPEROXIDE DISMUTASE; YOUNG ADULT;

EID: 82255179412     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2011.08.033     Document Type: Article

References (29)

1. Stengel B., Billon S., Van Dijk P.C., Jager K.J., Dekker F.W., Simpson K., Briggs J.D. Trends in the incidence of renal replacement therapy for end-stage renal disease in Europe, 1990-1999. Nephrol. Dial. Transplant. 2003, 18:1824-1833.
2. Jones C.A., Krolewski A.S., Rogus J., Xue J.L., Collins A., Warram J.H. Epidemic of end-stage renal disease in people with diabetes in the United States population: do we know the cause?. Kidney Int. 2005, 67:1684-1691.
3. Rossing P., Hougaard P., Borch-Johnsen K., Parving H.H. Predictors of mortality in insulin dependent diabetes: 10year observational follow up study. BMJ 1996, 313:779-784.
4. Valmadrid C.T., Klein R., Moss S.E., Klein B.E. The risk of cardiovascular disease mortality associated with microalbuminuria and gross proteinuria in persons with older-onset diabetes mellitus. Arch. Intern. Med. 2000, 160:1093-1100.
5. Pirart J., Lauvaux J.P., Rey W. Blood sugar and diabetic complications. N. Engl. J. Med. 1978, 298:1149.
6. The Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 1993, 329:977-986.
7. Marre M., Jeunemaitre X., Gallois Y., Rodier M., Chatellier G., Sert C., Dusselier L., Kahal Z., Chaillous L., Halimi S., Muller A., Sackmann H., Bauduceau B., Bled F., Passa P., Alhenc-Gelas F. Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulin-dependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group. J. Clin. Invest. 1997, 99:1585-1595.
8. Ewens K.G., George R.A., Sharma K., Ziyadeh F.N., Spielman R.S. Assessment of 115 candidate genes for diabetic nephropathy by transmission/disequilibrium test. Diabetes 2005, 54:3305-3318.
9. Young I.S., Woodside J.V. Antioxidants in health and disease. J. Clin. Pathol. 2001, 54:176-186.
10. Guidot D.M., McCord J.M., Wright R.M., Repine J.E. Absence of electron transport (Rho 0 state) restores growth of a manganese-superoxide dismutase-deficient Saccharomyces cerevisiae in hyperoxia. Evidence for electron transport as a major source of superoxide generation in vivo. J. Biol. Chem. 1993, 268:26699-26703.
11. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414:813-820.
12. Evans J.L., Goldfine I.D., Maddux B.A., Grodsky G.M. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr. Rev. 2002, 23:599-622.
13. Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005, 54:1615-1625.
14. Forbes J.M., Coughlan M.T., Cooper M.E. Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes 2008, 57:1446-1454.
15. Fridovich I. Superoxide radical and superoxide dismutases. Annu. Rev. Biochem. 1995, 64:97-112.
16. Marklund S.L. Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species. Biochem. J. 1984, 222:649-655.
17. Hadjadj S., Belloum R., Bouhanick B., Gallois Y., Guilloteau G., Chatellier G., Alhenc-Gelas F., Marre M. Prognostic value of angiotensin-I converting enzyme I/D polymorphism for nephropathy in type 1 diabetes mellitus: a prospective study. J. Am. Soc. Nephrol. 2001, 12:541-549.
18. Hadjadj S., Pean F., Gallois Y., Passa P., Aubert R., Weekers L., Rigalleau V., Bauduceau B., Bekherraz A., Roussel R., Dussol B., Rodier M., Marechaud R., Lefebvre P.J., Marre M. Different patterns of insulin resistance in relatives of type 1 diabetic patients with retinopathy or nephropathy: the Genesis France-Belgium Study. Diabetes Care 2004, 27:2661-2668.
19. Marre M., Claudel J.P., Ciret P., Luis N., Suarez L., Passa P. Laser immunonephelometry for routine quantification of urinary albumin excretion. Clin. Chem. 1987, 33:209-213.
20. Levey A.S., Bosch J.P., Lewis J.B., Greene T., Rogers N., Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann. Intern. Med. 1999, 130:461-470.
21. Kohner E.M. The lesions and natural history of diabetic retinopathy. Textbook of Diabetes 1991, 575-588. Blackwell Scientific, Oxford. J. Pickup, G. Williams (Eds.).
22. Milani P., Gagliardi S., Cova E., Cereda C. SOD1 transcriptional and posttranscriptional regulation and its potential implications in ALS. Neurol Res Int 2011, 2011:458427. 10.1155/2011/458427.
23. Cheverud J.M. A simple correction for multiple comparisons in interval mapping genome scans. Heredity 2001, 87:52-58.
24. Nyholt D.R. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet. 2004, 74:765-769.
25. Tregouet D.A., Escolano S., Tiret L., Mallet A., Golmard J.L. A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm. Ann. Hum. Genet. 2004, 68:165-177.
26. Al-Kateb H., Boright A.P., Mirea L., Xie X., Sutradhar R., Mowjoodi A., Bharaj B., Liu M., Bucksa J.M., Arends V.L., Steffes M.W., Cleary P.A., Sun W., Lachin J.M., Thorner P.S., Ho M., McKnight A.J., Maxwell A.P., Savage D.A., Kidd K.K., Kidd J.R., Speed W.C., Orchard T.J., Miller R.G., Sun L., Bull S.B., Paterson A.D. Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Genetics study. Diabetes 2008, 57:218-228.
27. Craven P.A., Melhem M.F., Phillips S.L., DeRubertis F.R. Overexpression of Cu2+/Zn2+ superoxide dismutase protects against early diabetic glomerular injury in transgenic mice. Diabetes 2001, 50:2114-2125.
28. DeRubertis F.R., Craven P.A., Melhem M.F., Salah E.M. Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction. Diabetes 2004, 53:762-768.
29. DeRubertis F.R., Craven P.A., Melhem M.F. Acceleration of diabetic renal injury in the superoxide dismutase knockout mouse: effects of tempol. Metabolism 2007, 56:1256-1264.