The female gubernaculum: Role in the embryology and development of the genital tract and in the possible genesis of malformations

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 159, Issue 2, 2011, Pages 426-432

  Acién, Pedro ^a   Sánchez Del Campo, Francisco ^a   Mayol, María José ^b   Acién, Maribel ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b University Hospital of San Juan   (Spain)

Author keywords

Accessory uterine masses; Female genital tract; Gubernaculum; Malformations; M llerian ducts; Rokitansky syndrome; Round ligament; Uterus

Indexed keywords

ANDROGEN; FIBROBLAST GROWTH FACTOR; MUELLERIAN INHIBITING FACTOR; TRANSCRIPTION FACTOR HOXA10;

ARTICLE; EMBRYOLOGY; FEMALE GENITAL SYSTEM; FEMALE GENITAL TRACT MALFORMATION; GONAD DEVELOPMENT; GUBERNACULUM; GUBERNACULUM HUNTERI; HUMAN; INGUINAL HERNIA; INVAGINATION; MUELLERIAN DUCT; MUSCLE CELL; MYOMETRIUM; PATHOPHYSIOLOGY; PRIORITY JOURNAL; ROKITANSKY SYNDROME; ROUND LIGAMENT OF UTERUS; UTERINE TUBE; UTERUS DIDELPHYS; UTERUS MALFORMATION; UTERUS TUMOR;

EID: 82255175038     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2011.07.040     Document Type: Article

References (33)

1. P. Van der Schoot Human (and some other primates') uterine teres ligament represents a mammalian developmental novelty Anat Rec 244 3 1996 402 415
2. T. Abe, and J.M. Hutson Calcitonine gene related peptide injected alters gubernaculum Ped Surg Int 9 1994 551 554
3. J.M.A. Emmen, A. McLuskey, I.M. Adham, W. Engel, J.A. Grootegoed, and A.O. Brinkmann Hormonal control of gubernaculum development Endocrinology 141 2000 4720 4727
4. P. Van der Schoot, B. Vigier, J. Prepin, J.P. Perchellet, and A. Gittenberger-de Groot Development of the gubernaculums and processus vaginalis in freemartinism: further evidence in support of a specific fetal testis hormone governing male-specific gubernacular development Anat Rec 241 2 1995 211 224
5. P. Van der Schoot, and J.M. Emmen Development: structure and function of the cranial suspensory ligaments of the mammalian gonads in a cross-species perspective; their possible role in effecting disturbed testicular descent Hum Reprod Update 2 5 1996 399 418
6. K.J. Barteczko, and M.I. Jacob The testicular descent in human origin, development and fate of the gubernaculum Hunteri, processus vaginalis peritonei, and gonadal ligaments Adv Anat Embryol Cell Biol 156/ III-X 2000 1 98
7. J.M.A. Emmen, A.M. Luskey, J.A. Grootegoed, and A.O. Brinkmann Androgen action during male sex differentiation includes suppression of cranial suspensory ligament development Hum Reprod 13 5 1998 1272 1280
8. H. Niikura, S. Okamoto, and S. Nagase Fetal development of the human Gubernaculum with special reference to the fasciae and muscles around it Clin Anat 21 2008 547 557
9. S.N. Biasutto, E. Repetto, M.M. Aliendo, and V.N. Borghino Inguinal canal development: the muscular wall and the role of the gubernaculum Clin Anat 22 5 2009 614 618
10. P. Acién Embryological observations on the female genital tract Hum Reprod 7 4 1992 437 445
11. P. Acién, M. Acién, and M.L. Sánchez-Ferrer Complex malformations of the female genital tract. New types and revision of classification Hum Reprod 19 10 2004 2377 2384
12. M.L. Sánchez-Ferrer, M.I. Acién, F. Sánchez del Campo, M.J. Mayol-Belda, and P. Acién Experimental contributions to the study of the embryology of the vagina Hum Reprod 21 6 2006 1623 1628
13. P. Acién, and M. Acién Malformations of the female genital tract and embryological bases Curr Women's Health Rev 3 2007 248 288
14. S. Mohsin, and J.N. Pennefather The sympathetic innervation of the mammalian ovary. A review of pharmacological and histological studies Clin Exp Pharmacol Physiol 6 3 1979 335 354
15. Z. Hrabovszky, N. Di Pilla, T. Yap, P.J. Farmer, J.M. Hutson, and J.B. Carlin Role of the gubernacular bulb in cremaster muscle development in rats Anat Rec 267 2 2002 159 165
16. S.S. Nightingale, P. Western, and J.M. Hutson The migrating gubernaculum grows like a limb bud J Pediatr Surg 43 2 2008 387 390
17. J.M. Hutson A biphasic model for the hormonal control of testicular descent Lancet 2 1985 419 421
18. D.R. McMahon, S.A. Kramer, and D.A. Husmann Antiandrogen induced cryptorchidism in the pig is associated with failed gubernacular regression and epididymal malformations J Urol 154 1995 553 557
19. P. Van der Schoot, and W. Elger Androgen-induced prevention of the outgrowth of cranial gonadal suspensory ligaments in fetal rats J Androl 13 6 1992 534 542
20. S.W. Beasley, and J.M. Hutson The role of gubernaculum in testicular descent J Urol 140 5 1988 1191 1193
21. I.E. Scheffer, J.M. Hutson, G.L. Warne, and G. Ennis Extreme virilization in patients with congenital adrenal hyperplasia fails to induce descent of the ovary Ped Surg Int 3 1988 165 168
22. L. Testut, and A. Latarjet Tratado de Anatomía Humana. Tomo IV 1960 Salvat Editores, S.A. Barcelona
23. K.L. Moore, and T.V.N. Persaud The developing human. Clinically oriented embryology 5th ed. 1993 W.B. Saunders Company
24. C.S. Rhee, J.S. Kim, S.K. Woo, and S.J. Suh MRI of round ligament leiomyoma associated with Mayer-Rokitansky-Kuster-Hauser syndrome Abdom Imaging 24 1999 202 204
25. M. Lamarca, R. Navarro, M.E. Ballesteros, S. Garcia-Aguirre, M.P. Conte, and J.A. Duque Leiomyomas in both uterine remnants in a woman with the Mayer-Rokitansky-Küster-Hauser syndrome Fertil Steril 91 3 2009 931.e13-5
26. G.B. Candiani Vercellini, P. Vercellini, L. Fedele, N. Vendola, S. Carinelli, and V. Scaglione Inguinal endometriosis: pathogenetic and clinical implications Obstet Gynecol 78 1991 191 194
27. M. Kamio, T. Nagata, H. Yamasaki, M. Yoshinaga, and T. Douchi Inguinal hernia containing functioning, rudimentary uterine horn an endometriosis Obstet Gynecol 113 2009 563 566
28. A. Kriplani, N. Banerjee, A.C. Aminni, K. Kucheria, and D. Takkar Hernia uterus inguinale in a 46,XX female. A case report J Reprod Med 45 2000 48 50
29. M.M. Garrey, A.D.T. Govan, C.H. Hodge, and R. Callender Gynaecology illustrated 1972 Edinburg Churchill Livingstone
30. J.A. Rock, T. Parmley, A.A. Murphy, and H.W. Jones Jr. Malposition of the ovary associated with uterine anomalies Fertil Steril 45 1986 561 563
31. H. Dabirashrafi, K. Mohammad, and N. Moghadami-Tabrizi Ovarian malposition in women with uterine anomalies Obstet Gynecol 83 1994 293 294
32. W. Ombelet, M. Grieten, and P. DeNeubourg Undescended ovary and unicornuate uterus: simplified diagnosis by the use of clomiphene citrate ovarian stimulation and magnetic resonance imaging (MRI) Hum Reprod 18 2003 858 862
33. P. Acién, M. Acién, F. Fernández, M.J. Mayol, and I. Aranda The cavitated accessory uterine mass: a müllerian anomaly in women with an otherwise normal uterus Obstet Gynecol 116 5 2010 1101 1109