Lipid nanoparticles as carrier for octyl-methoxycinnamate: In vitro percutaneous absorption and photostability studies

Journal of Pharmaceutical Sciences

Volumn 101, Issue 1, 2012, Pages 301-311

  Puglia, Carmelo ^a   Bonina, Francesco ^a   Rizza, Luisa ^a   Blasi, Paolo ^b   Schoubben, Aurelie ^b   Perrotta, Rosario ^c   Tarico, Maria Stella ^c   Damiani, Elisabetta ^d  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c Azienda Ospedaliera per l'Emergenza Cannizzaro   (Italy)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

Calorimetry (DSC); In vitro models; Nanoparticles; Particle size; Percutaneous; Photodegradation; Skin; Ultrasound

Indexed keywords

4 METHOXYCINNAMIC ACID 2 ETHYLHEXYL ESTER; DRUG CARRIER; SOLID LIPID NANOPARTICLE;

ARTICLE; CALORIMETRY; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MICROEMULSION; PARTICLE SIZE; PHOTODEGRADATION; SKIN ABSORPTION; ULTRAVIOLET A RADIATION;

EID: 82255174938     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22741     Document Type: Article

References (42)

1. Luckey TD. 1999. Nurture with ionizing radiation: A provocative hypothesis. Nutr Cancer 34:1-11.
2. Butt ST, Christensen T. 2001. Toxicity and phototoxicity of chemical sun filters. Radiat Prot Dosim 91:283-286.
3. Kimura K, Katoh T. 1995. Photo allergic contact dermatitis from the sunscreen ethylhexyl-p-methoxycinnamate (Parsol MCX). Contact Dermatitis 32:304-305.
4. Pattanaargson S, Limphong P. 2001. Stability of octyl methoxycinnamate and identification of its photo-degradation product. Int J Cosmet Sci 23:153-160.
5. Jiang R, Roberts MS, Collins DM, Benson HA. 1999. Absorption of sunscreens across human skin: An evaluation of commercial products for children and adults. Br J Clin Pharmacol 48:635-637.
6. Puglia C, Bonina F, Castelli F, Micieli D, Sarpietro MG. 2009. Evaluation of percutaneous absorption of the repellent DEET and the sunscreen octyl methoxy cinnamate (OMC) loaded solid lipid nanoparticles: An in vitro study. J Pharm Pharmacol 61:1013-1019.
7. Montenegro L, Carbone C, Puglisi G. 2011. Vehicle effects on in vitro release and skin permeation of octylmethoxycinnamate from microemulsions. Int J Pharm 405:162-168.
8. Yener G, Incegül T, Yener N. 2003. Importance of using solid lipid microspheres as carriers for UV filters on the example octyl methoxy cinnamate. Int J Pharm 258:203-207.
9. Golmohammadzadeh S, Jaafarixx MR, Khalili N. 2008. Evaluation of liposomal and conventional formulations of octyl methoxycinnamate on human percutaneous absorption using the stripping method. J Cosmet Sci 59:385-398.
10. Müller RH, Mäder K, Gohla S. 2000. Solid lipid nanoparticles (SLN) for controlled drug delivery-A review of the state of the art. Eur J Pharm Biopharm 50:161-177.
11. Müller RH, Radtke M, Wissing SA. 2002. Nanostructured lipid matrices for improved microencapsulation of drugs. Int J Pharm 242:121-128.
12. Pardeike J, Hommoss A, Müller RH. 2009. Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int J Pharm 366:170-184.
13. Wissing SA, Müller RH. 2001. Solid lipid nanoparticles (SLN)-A novel carrier for UV blockers. Pharmazie 56:783-786.
14. Müller RH, Radtke M, Wissing SA. 2002. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv Drug Deliv Rev 54:S131-S155.
15. Puglia C, Sarpietro MG, Bonina F, Castelli F, Zammataro M, Chiechio S. 2011. Development, characterization, and in vitro and in vivo evaluation of benzocaine- and lidocaine-loaded nanostructrured lipid carriers. J Pharm Sci 100:1892-1899.
16. Bunjes H, Unruh T. 2007. Characterization of lipid nanoparticles by differential calorimetry, X-ray and neutron scattering. Adv Drug Deliv Rev 59:379-402.
17. Kligman AM, Christophers E. 1963. Preparation of isolated sheets of human stratum corneum. Arch Dermatol 88:702-705.
18. Swarbrick J, Lee G, Brom J. 1982. Drug permeation through human skin. I. Effects of storage conditions of skin. J Invest Dermatol 78:63-66.
19. Bronaugh RL, Stewart RF, Simon M. 1986. Methods for in vitro percutaneous absorption studies VII: Use of excised human skin. J Pharm Sci 75:1094-1097.
20. Toitou E, Fabin B. 1988. Altered skin permeation of highly lipophilic molecule: Tetrahydrocannabinol. Int J Pharm 43:17-22.
21. Puglia C, Tropea S, Rizza L, Santagati NA, Bonina F. 2005. In vitro percutaneous absorption studies and in vivo evaluation of anti-inflammatory activity of essential fatty acids (EFA) from fish oil extracts. Int J Pharm 299:41-48.
22. Damiani E, Astolfi P, Giesinger J, Ehlis T, Herzog B, Greci L, Baschong W. 2010. Assessment of the photo-degradation of UV-filters and radical-induced peroxidation in cosmetic sunscreen formulations. Free Radic Res 44:304-312.
23. Seite S, Moyal D, Richard S, de Rigal J, Leveque JL, Hourseau C, Fourtanier AJ. 1998. Mexoryl SX: A broad absorption UVA filter protects human skin from the effects of repeated suberythemal doses of UVA. Photochem Photobiol B 44:69-76.
24. Buege JA, Aust SD. 1978. Microsomal lipid peroxidation. Methods Enzymol 52:302-310.
25. Puglia C, Filosa R, Peduto A, de Caprariis P, Rizza L, Bonina F, Blasi P. 2006. Evaluation of alternative strategies to optimize ketorolac transdermal delivery. AAPS PharmSciTech 7:64.
26. Puglia C, Blasi P, Rizza L, Schoubben A, Bonina F, Rossi C, Ricci M. 2008. Lipid nanoparticles for prolonged topical delivery: An in vitro and in vivo investigation. Int J Pharm 357:295-304.
27. Ricci M, Puglia C, Bonina F, Di Giovanni C, Giovagnoli S, Rossi C. 2005. Evaluation of indomethacin percutaneous absorption from nanostructured lipid carriers (NLC): In vitro and in vivo studies. J Pharm Sci 94:1149-1159.
28. Castelli F, Puglia C, Sarpietro MG, Rizza L, Bonina F. 2005. Characterization of indomethacin loaded lipid nanoparticles by differential scanning calorimetry. Int J Pharm 304:231-238.
29. Xia Q, Saupe A, Müller RH, Souto EB. 2007. Nanostructured lipid carriers as novel carrier for sunscreen formulations. Int J Cosmet Sci 29:473-482.
30. Hunter RJ. 1993. Foundations of colloid science. Vol. I. Oxford: Clarendon Press.
31. Siekmann B, Westesen K. 1994. Thermoanalysis of the recrystallization process of melt-homogenized glyceride nanoparticles. Colloids Surf B Biointerfaces 3:159-175.
32. Jenning V, Thünemann AF, Gohla SH. 2000. Characterisation of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids. Int J Pharm 199:167-177.
33. Zimmermann E, Souto EB, Müller RH. 2005. Physicochemical investigations on the structure of drug-free and drug-loaded solid lipid nanoparticles (SLN) by means of DSC and 1H NMR. Pharmazie 60:508-513.
34. Freitas C, Müller RH. 1999. Correlation between long-term stability of solid lipid nanoparticles (SLN) and crystallinity of the lipid phase. Eur J Pharm Biopharm 47:125-132.
35. Hamdani J, Moës AJ, Amighi K. 2003. Physical and thermal characterisation of Precirol and Compritol as lipophilic glycerides used for the preparation of controlled-release-matrix pellets. Int J Pharm 260:47-57.
36. Wissing SA, Müller RH. 2003. The influence of solid lipid nanoparticles on skin hydration and viscoelasticity-In vivo study. Eur J Pharm Biopharm 56:67-72.
37. Wissing S, Lippacher A, Müller R. 2001. Investigations on the occlusive properties of solid lipid nanoparticles (SLN). J Cosmet Sci 52:313-324.
38. Huong SP, Andrieu V, Reynier JP, Rocher E, Fourneron JD. 2007. The photoisomerization of the sunscreen ethylhexyl p-methoxy cinnamate and its influence on the sun protection factor. J Photochem Photobiol A Chem 186:65-70.
39. Broadbent JK, Martincigh BS, Raynor MW, Salter LF, Moulder R, Sjoberg P, Markides KE. 1996. Capillary supercritical fluid chromatography combined with atmospheric pressure chemical ionization mass spectrometry for the investigation of photoproduct formation in the sunscreen absorber 2-ethylhexyl-p-methoxycinnamate. J Chromatogr A 732:101-110.
40. Morliere P, Moysan A, Tirache I. 1995. Action spectrum for UV-induced lipid peroxidation in cultured human skin fibroblasts. Free Radic Biol Med 19:365-371.
41. Polte T, Tyrrell RM. 2004. Involvement of lipid peroxidation and organic peroxides in UVA-induced matrix metalloproteinase-1 expression. Free Radic Biol Med 36:1566-1574.
42. Esterbauer H, Cheeseman KH. 1990. Determination of aldehydic lipid peroxidation products: Malodialdehyde and 4 hydroxynonenal. Methods Enzymol 186:407-421.