Meningococcal surface fibril (Msf) binds to activated vitronectin and inhibits the terminal complement pathway to increase serum resistance

Molecular Microbiology

Volumn 82, Issue 5, 2011, Pages 1129-1149

  Griffiths, Natalie J ^a   Hill, Darryl J ^a   Borodina, Elena ^a   Sessions, Richard B ^b   Devos, Nathalie I ^c   Feron, Christiane M ^c   Poolman, Jan T ^c,d   Virji, Mumtaz ^a  

^a Schools of Cellular and Molecular Medicine   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

^d CRUCELL HOLLAND BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL PROTEIN; HEPARIN; MENINGOCOCCAL SURFACE FIBRIL; OPC PROTEIN; UNCLASSIFIED DRUG; VITRONECTIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL KILLING; COMPLEMENT INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; MUTANT; NEISSERIA MENINGITIDIS; NONHUMAN; ORGANISMAL INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING;

ADHESINS, BACTERIAL; BLOOD BACTERICIDAL ACTIVITY; COMPLEMENT MEMBRANE ATTACK COMPLEX; HOST-PATHOGEN INTERACTIONS; IMMUNE EVASION; MEMBRANE PROTEINS; MODELS, MOLECULAR; NEISSERIA MENINGITIDIS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; VITRONECTIN;

BACTERIA (MICROORGANISMS); NEISSERIA MENINGITIDIS;

EID: 82155166266     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2011.07876.x     Document Type: Article

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