The quest for predictive immune biomarkers

Clinical and Experimental Allergy

Volumn 41, Issue 12, 2011, Pages 1656-1659

  Hayglass, K T ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CELL ADHESION MOLECULE; CHEMOKINE; CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOMODULATING AGENT; INTERLEUKIN 12; INTERLEUKIN 5; LYMPHOKINE;

ALLERGIC ASTHMA; ANTIBODY RESPONSE; CELL MIGRATION; CYTOKINE PRODUCTION; ECZEMA; EDITORIAL; HUMAN; IMMUNE RESPONSE; IMMUNE STATUS; IMMUNOMODULATION; IMMUNOREGULATION; MULTIPLE SCLEROSIS; PEANUT ALLERGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FOLDING; SENSITIZATION; TH1 CELL; TH17 CELL; TH2 CELL;

CHEMOKINES; ECZEMA; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; MALE; TH1 CELLS; TH2 CELLS;

EID: 82155165872     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03884.x     Document Type: Editorial

References (12)

1. Jerne NK. The complete solution of immunology. Australas Ann Med 1969; 18:345-8.
2. Jerne NK. Waiting for the End, Cold Spring Harbor Symp. on Quant. Biology 1967; 32:591-603.
3. Akdis M, Burgler S, Crameri R et al. Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases. J Allergy Clin Immunol 2011; 127:701-21.
4. Haribhai D, Williams JB, Jia S et al. A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. Immunity 2011; 35:109-22.
5. Altar CA, Amakye D, Bounos D et al. A prototypical process for creating evidentiary standards for biomarkers and diagnostics. Clin Pharmacol Ther 2008; 83:368-71.
6. Abrahamsson TR, Abelius M, Forsberg A, Björkstén B, Jenmalm MC. A Th1/Th2-associated chemokine imbalance during infancy in children developing eczema, wheeze and sensitization. Clin Exp Allergy. 2011; 41:1729-39.
7. McDonald B, Kubes P. Chemokines: sirens of neutrophil recruitment-but is it just one song? Immunity 2010; 33:148-9.
8. Viola A, Luster AD. Chemokines and their receptors: drug targets in immunity and inflammation, Annu Rev Pharmacol Toxicol 2008; 48:171-97.
9. Campbell JD, Gangur V, Simons FE, HayGlass KT. Allergic humans are hyporesponsive to a CXCR3 ligand-mediated Th1 immunity-promoting loop. FASEB J 2004; 18:329-31.
10. Koelink PJ, Overbeek SA, Braber S et al. Targeting chemokine receptors in chronic inflammatory diseases: an extensive review. Pharmacol Ther. 2011 Aug 1. [Epub ahead of print]
11. Holgate ST. Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches? J Allergy Clin Immunol. 2011; 128:495-505.
12. Pencina MJ, D'Agostino RB, Vasan RS. Statistical methods for assessment of added usefulness of new biomarkers. Clin Chem Lab Med 2010; 48:1703-11.