Preventive action of curcumin in experimental acute pancreatitis in mouse

Indian Journal of Medical Research

Volumn 134, Issue 11, 2011, Pages 717-724

  Yu, Wen Guang ^a   Xu, Gang ^a   Ren, Gui Jie ^a   Xu, Xia ^a   Yuan, Hui Qing ^a   Qi, Xiao Li ^a   Tian, Ke Li ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Acute pancreatitis (AP); Curcumin; NF B; PPAR ; TNF

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ALANINE AMINOTRANSFERASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; CERULETIDE; CURCUMIN; LIPOPOLYSACCHARIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PANCREATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME BLOOD LEVEL; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ALANINE TRANSAMINASE; AMYLASES; ANILIDES; ANIMALS; CAERULEIN; CELL NUCLEUS; CURCUMA; CURCUMIN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; NF-KAPPA B; PANCREATITIS; PLANT EXTRACTS; PPAR GAMMA; TRANSAMINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 82155164382     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Omdal T, Dale J, Lie SA, Iversen KB, Flaatten H, Ovrebo K. Time trends in incidence, etiology, and case fatality rate of the first attack of acute pancreatitis. Scand J Gastroenterol 2011; 46: 1389-98.
2. Sandzén B, Rosenmüller M, Haapamki MM, Nilsson E, Stenlund HC, Oman M. First attack of acute pancreatitis in Sweden 1988 - 2003: incidence, aetiological classification, procedures and mortality - a register study. BMC Gastroenterol 2009; 9: 18.
3. Yadav D, Lowenfels AB. Trends in the epidemiology of the first attack of acute pancreatitis: a systematic review. Pancreas 2006; 33: 323-30.
4. Spanier BW, Dijkgraaf MG, Bruno MJ. Epidemiology, etiology and outcome of acute and chronic pancreatitis: An update. Best Pract Res Clin Gastroenterol 2008; 22: 45-63.
5. Czako L, Takacs T, Varga IS, Hai DQ, Tiszlavicz L, Hegyi P, et al. The pathogenesis of L-argentine-induced acute necrotizing pancreatitis: inflammatory mediators and endogenous cholecystokinin. J Physiol Paris 2000; 94: 43-50.
6. Chen CC, Wang SS, Lee FY, Chang FY, Lee SD. Proinflammatory cytokines in early assessment of the prognosis of acute pancreatitis. Am J Gastroenterol 1999; 94: 213-8.
7. Kim H, Seo JY, Roh KH, Lim JW, Kim KH. Suppression of NF-kappaB activation and cytokine production by N-acetylcysteine in pancreatic acinar cells. Free Radic Biol Med 2000; 29: 674-83.
8. Osman MO, Gesser B, Mortensen JT, Matsushima K, Jensen SL, Larsen CG. Profles of pro-inflammatory cytokines in the serum of rabbits after experimentally induced acute pancreatitis. Cytokine 2002; 17: 53-9.
9. Shifrin AL, Chirmule N, Zhang Y, Raper SE. Macrophage ablation attenuates adenoviral vector-induced pancreatitis. Surgery 2005; 137: 545-51.
10. Abe Y, Hashimoto S, Horie T. Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol Res 1999; 39: 41-7.
11. Gukovsky I, Reyes CN, Vaquero EC, Gukovskaya AS, Pandol SJ. Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol 2003; 284: G85-95.
12. Kim HY, Park EJ, Joe EH, Jou I. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J Immunol 2003; 171: 6072-9.
13. Chen F, Wang M, O'Connor JP, He M, Tripathi T, Harrison LE. Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta. J Cell Biochem 2003; 90: 732-44.
14. Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, Aggarwal BB. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaβ-regulated gene products. Cancer Res 2007; 67: 3853-61.
15. Xu J, Fu Y, Chen A. Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth. Am J Physiol Gastrointest Liver Physiol 2003; 285: G20-30.
16. Niederau C, Ferrell LD, Grendell JH. Caerulein-induced acute necrotizing pancreatitis in mice: Protective effects of proglumide, benzotript, and secretin. Gastroenterology 1985; 88: 1192-204.
17. Shimizu T, Shiratori K, Sawada T, Kobayashi M, Hayashi N, Saotome H, et al. Recombinant human interleukin-11 decreases severity of acute necrotizing pancreatitis in mice. Pancreas 2000; 21: 134-40.
18. Schmidt J, Lewandrowsi K, Warshaw AL, Compton CC, Rattner DW. Morphometric characteristics and homogeneity of a new model of acute pancreatitis in the rat. Int J Pancreatol 1992; 12: 41-51.
19. Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation,invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett 2008; 269: 199-225.
20. Raraty MG, Connor S, Criddle DN, Sutton R, Neoptolemos JP. Acute pancreatitis and organ failure: pathophysiology, natural history, and management strategies. Curr Gastroenterol Rep 2004; 6: 99-103.
21. Gómez-Cambronero LG, Sabater L, Pereda J, Cassinello N, Camps B, Viña J, et al. Role of cytokines and oxidative stress in the pathophysiology of acute pancreatitis: therapeutical implications. Curr Drug Targets Inflamm Allergy 2002; 1: 393-403.
22. Fu Y, Zheng S, Lin J, Ryerse J, Chen A. Curcumin protects the rat liver from CCl4-caused injury and fbrogenesis by attenuating oxidative stress and suppressing inflammation. Mol Pharmacol 2008; 73: 399-409.
23. Gulcubuk A, Altunatmaz K, Sonmez K, Haktanir-Yatkin D, Uzun H, Gurel A, et al. Effects of curcumin on tumour necrosis factor-alpha and interleukin-6 in the late phase of experimental acute pancreatitis. J Vet Med A Physiol Pathol Clin Med 2006; 53: 49-54.
24. Samuhasaneeto S, Thong-Ngam D, Kulaputana O, Suyasunanont D, Klaikeaw N. Curcumin decreased oxidative stress, inhibited NF-kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats. J Biomed Biotechnol 2009; 2009: 981963.
25. Hayden MS, Ghosh S. Signaling to NF-kappaB. Genes Dev 2004; 18: 2195-224.
26. Aggarwal BB, Bhatt ID, Ichikawa H, Ahn KS, Sethi G, Sandur SK, et al. Curcumin: Biological and medicinal properties. In: Ravindran PN, Nirmal Babu K, Shivaraman, editors. Turmeric: the genus Curcuma. Boca Raton, FL: The CRC Press; 2006. p. 297-368.
27. Yoon H, Liu RH. Effect of selected phytochemicals and apple extracts on NF-kappaB activation in human breast cancer MCF-7 cells. J Agric Food Chem 2007; 55: 3167-73.
28. Aggarwal BB, Surh YJ, Shishodia S. The molecular targets and therapeutic uses of curcumin in health and disease. Adv Exp Med Biol 2007; 595: 1-512.
29. Lin J, Chen A. Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells. Lab Invest 2008; 88: 529-40.
30. Rinwa P, Kaur B, Jaggi AS, Singh N. Involvement of PPAR-gamma in curcumin-mediated benefcial effects in experimental dementia. Naunyn Schmiedebergs Arch Pharmacol 2010; 381: 529-39.
31. Kang Q, Chen A. Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1. Lab Invest 2009; 89: 1275-90.
32. Jacob A, Wu R, Zhou M, Wang P. Mechanism of the antiinflammatory effect of curcumin: PPAR-γ activation. PPAR Res 2007; 2007: 89369.
33. Siddiqui AM, Cui X, Wu R, Dong W, Zhou M, Hu M, et al. The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma. Crit Care Med 2006; 34: 1874-82.
34. Su CG, Wen X, Bailey ST, Jiang W, Rangwala SM, Keilbaugh SA, et al. A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. J Clin Invest 1999; 104: 383-9.
35. Chinetti G, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors and inflammation: from basic science to clinical applications. Int J Obes Relat Metab Disord 2003; 27 (Suppl 3): S41-5.
36. Ghosh SS, Massey HD, Krieg R, Fazelbhoy ZA, Ghosh S, Sica DA, et al. Curcumin ameliorates renal failure in 5/6 nephrectomized rats: role of inflammation. Am J Physiol Renal Physiol 2009; 296: F1146-57.