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Volumn 8, Issue 8, 2011, Pages 876-882

Effects of the putative cognitive-enhancing ampakine, CX717, on attention and object recognition memory

Author keywords

Ampakines; Cognitive dysfunction; Nootropic drugs; Rats; Vestibular lesions

Indexed keywords

CX 717; NOOTROPIC AGENT; UNCLASSIFIED DRUG;

EID: 82055176903     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/156720511798192709     Document Type: Article
Times cited : (18)

References (44)
  • 2
    • 0027053905 scopus 로고
    • Factors regulating the magnitude of LTP induced by theta pattern stimulation
    • Arai A, Lynch G. Factors regulating the magnitude of LTP induced by theta pattern stimulation. Brain Res 598: 173-84 (1992).
    • (1992) Brain Res , vol.598 , pp. 173-184
    • Arai, A.1    Lynch, G.2
  • 3
    • 0029035791 scopus 로고
    • Effect of thiocyanate on AMPA receptor mediated responses in excised patches and hippocampal slices
    • Arai A, Silberg J, Kessler M, Lynch G. Effect of thiocyanate on AMPA receptor mediated responses in excised patches and hippocampal slices. Neurosci 66: 815-27 (1995).
    • (1995) Neurosci , vol.66 , pp. 815-827
    • Arai, A.1    Silberg, J.2    Kessler, M.3    Lynch, G.4
  • 4
    • 0035077550 scopus 로고    scopus 로고
    • Member of the ampakine class of memory enhancers prolongs the single channel opening time of reconstituted AMPA receptors
    • Suppiramaniam V, Bahr BA, Sinnarajah S, Owens K, Rogers G, Yilma S, et al. Member of the ampakine class of memory enhancers prolongs the single channel opening time of reconstituted AMPA receptors. Synapse 40: 154-58 (2001).
    • (2001) Synapse , vol.40 , pp. 154-158
    • Suppiramaniam, V.1    Bahr, B.A.2    Sinnarajah, S.3    Owens, K.4    Rogers, G.5    Yilma, S.6
  • 6
    • 0031148706 scopus 로고    scopus 로고
    • Evidence that a positive modulator of AMPA-type glutamate receptors improves delayed recall in aged humans
    • Lynch G, Granger R, Ambros-Ingerson J, Davis M, Kessler M, Schehr RS. Evidence that a positive modulator of AMPA-type glutamate receptors improves delayed recall in aged humans. Exp Neurol 145: 89-92 (1997).
    • (1997) Exp Neurol , vol.145 , pp. 89-92
    • Lynch, G.1    Granger, R.2    Ambros-Ingerson, J.3    Davis, M.4    Kessler, M.5    Schehr, R.S.6
  • 7
    • 59449102348 scopus 로고    scopus 로고
    • Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717
    • Hampson RE, España RA, Rogers GA, Porrino LJ, Deadwyler SA. Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717. Psychopharmacol (Berl) 202(1-3): 355-69 (2009).
    • (2009) Psychopharmacol (Berl) , vol.202 , Issue.1-3 , pp. 355-369
    • Hampson, R.E.1    España, R.A.2    Rogers, G.A.3    Porrino, L.J.4    Deadwyler, S.A.5
  • 8
    • 0032053403 scopus 로고    scopus 로고
    • Facilitative effects of the ampakine CX516 on short-term memory in rats: Enhancement of delayed-nonmatch-to-sample performance
    • Hampson RE, Rogers G, Lynch G, Deadwyler SA. Facilitative effects of the ampakine CX516 on short-term memory in rats: enhancement of delayed-nonmatch-to-sample performance. J Neurosci 18: 2740-47 (1998).
    • (1998) J Neurosci , vol.18 , pp. 2740-2747
    • Hampson, R.E.1    Rogers, G.2    Lynch, G.3    Deadwyler, S.A.4
  • 9
    • 24944535699 scopus 로고    scopus 로고
    • Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates
    • Porrino LJ, Daunais JB, Rogers GA, Hampson RE, Deadwyler SA. Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates. PLoS Biol 3: 1639-52 (2005).
    • (2005) PLoS Biol , vol.3 , pp. 1639-1652
    • Porrino, L.J.1    Daunais, J.B.2    Rogers, G.A.3    Hampson, R.E.4    Deadwyler, S.A.5
  • 10
    • 34249079802 scopus 로고    scopus 로고
    • Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers
    • Wezenberg E, Verkes RJ, Ruigt GS, Hulstijn W, Sabbe BG. Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers. Neuropsychopharmacol 32(6): 1272-83 (2007).
    • (2007) Neuropsychopharmacol , vol.32 , Issue.6 , pp. 1272-1283
    • Wezenberg, E.1    Verkes, R.J.2    Ruigt, G.S.3    Hulstijn, W.4    Sabbe, B.G.5
  • 12
    • 38149132338 scopus 로고    scopus 로고
    • A placebo-controlled add-on trial of the ampakine, CX516, for cognitive deficits in schizophrenia
    • Goff DC, Lamberti JS, Leon AC, Green MF, Miller AL, Patel J, et al. A placebo-controlled add-on trial of the ampakine, CX516, for cognitive deficits in schizophrenia. Neuropsychopharmacol 33(3): 465-72 (2008).
    • (2008) Neuropsychopharmacol , vol.33 , Issue.3 , pp. 465-472
    • Goff, D.C.1    Lamberti, J.S.2    Leon, A.C.3    Green, M.F.4    Miller, A.L.5    Patel, J.6
  • 13
    • 77957716183 scopus 로고    scopus 로고
    • The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: A subchronic, dose-ranging study in rats
    • Hamlyn E, Brand L, Shahid M, Harvey BH. The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: a subchronic, dose-ranging study in rats. Behav Pharmacol 20(7): 662-7 (2009).
    • (2009) Behav Pharmacol , vol.20 , Issue.7 , pp. 662-667
    • Hamlyn, E.1    Brand, L.2    Shahid, M.3    Harvey, B.H.4
  • 14
    • 70649098158 scopus 로고    scopus 로고
    • Positive modulation of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid (AMPA) receptors reverses sub-chronic PCP-induced deficits in the novel object recognition task in rats
    • Damgaard T, Larsen DB, Hansen SL, Grayson B, Neill JC, Plath N. Positive modulation of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid (AMPA) receptors reverses sub-chronic PCP-induced deficits in the novel object recognition task in rats. Behav Brain Res 207(1): 144-50 (2010).
    • (2010) Behav Brain Res , vol.207 , Issue.1 , pp. 144-150
    • Damgaard, T.1    Larsen, D.B.2    Hansen, S.L.3    Grayson, B.4    Neill, J.C.5    Plath, N.6
  • 15
    • 63849151219 scopus 로고    scopus 로고
    • Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice
    • Simmons DA, Rex CS, Palmer L, Pandyarajan V, Fedulov V, Gall CM, et al. Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proc Natl Acad Sci USA 106(12): 4906-11 (2009).
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.12 , pp. 4906-4911
    • Simmons, D.A.1    Rex, C.S.2    Palmer, L.3    Pandyarajan, V.4    Fedulov, V.5    Gall, C.M.6
  • 16
    • 0036667175 scopus 로고    scopus 로고
    • CX-516 Cortex pharmaceuticals
    • Danysz W. CX-516 Cortex pharmaceuticals. Curr Opin Investig Drugs 3(7): 1081-8 (2002).
    • (2002) Curr Opin Investig Drugs , vol.3 , Issue.7 , pp. 1081-1088
    • Danysz, W.1
  • 17
    • 0036392579 scopus 로고    scopus 로고
    • The 5-choice serial reaction time task: Behavioural pharmacology and functional neurochemistry
    • Robbins TW. The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry. Psychopharmacol 163: 362-80 (2002).
    • (2002) Psychopharmacol , vol.163 , pp. 362-380
    • Robbins, T.W.1
  • 18
    • 43149092475 scopus 로고    scopus 로고
    • Robbins TW The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats
    • Bari A, Dalley JW, Robbins TW The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats. Nat Protocol 3: 759-67 (2008).
    • (2008) Nat Protocol , vol.3 , pp. 759-767
    • Bari, A.1    Dalley, J.W.2
  • 19
    • 0141828631 scopus 로고    scopus 로고
    • Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulate, infralimbic and orbitofrontal cortex in the rat: Differential effects on selectivity, impulsivity and compulsivity
    • Chudasama Y, Passetti F, Rhodes SEV, Lopian D, Desai A, et al. Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulate, infralimbic and orbitofrontal cortex in the rat: differential effects on selectivity, impulsivity and compulsivity. Behav Brain Res 146: 105-19 (2003).
    • (2003) Behav Brain Res , vol.146 , pp. 105-119
    • Chudasama, Y.1    Passetti, F.2    Rhodes, S.E.V.3    Lopian, D.4    Desai, A.5
  • 20
    • 67349089886 scopus 로고    scopus 로고
    • Evidence for deficits in a 5 choice serial reaction time task in rats with bilateral vestibular deafferentation
    • Zheng Y, Balabhadrapatruni S, Munn O, Masumura C, Darlington CL, Smith PF. Evidence for deficits in a 5 choice serial reaction time task in rats with bilateral vestibular deafferentation. Behav. Brain Res 203: 113-17 (2009).
    • (2009) Behav. Brain Res , vol.203 , pp. 113-117
    • Zheng, Y.1    Balabhadrapatruni, S.2    Munn, O.3    Masumura, C.4    Darlington, C.L.5    Smith, P.F.6
  • 21
    • 84863983609 scopus 로고    scopus 로고
    • Sacculocolic reflex in patients with dementia: is it possible to use it for early diagnosis?
    • In Press
    • Birdane L, Incesulu A, Gurbuz MK, Ozbabalik D. Sacculocolic reflex in patients with dementia: is it possible to use it for early diagnosis? Neurol Sci (2011, in press).
    • (2011) Neurol Sci
    • Birdae, L.1    Incesulu, A.2    Gurbuz, M.K.3    Ozbalik, D.4
  • 23
    • 0034157614 scopus 로고    scopus 로고
    • Synaptic alterations in the vestibulocerebellar system in Alzheimer's disease--a Golgi and electron microscope study
    • Baloyannis SJ, Manolidis SL, Manolidis LS. Synaptic alterations in the vestibulocerebellar system in Alzheimer's disease--a Golgi and electron microscope study. Acta Otolaryngol 120(2): 247-50 (2000).
    • (2000) Acta Otolaryngol , vol.120 , Issue.2 , pp. 247-250
    • Baloyannis, S.J.1    Manolidis, S.L.2    Manolidis, L.S.3
  • 24
    • 0028131327 scopus 로고
    • Neurofibrillary tangles without cell loss in the lateral vestibular nucleus of patients with Alzheimer's disease
    • Ransmayr G, Benesch H, Nowakowski C, Künig G, Heinsen H, Riederer P, et al. Neurofibrillary tangles without cell loss in the lateral vestibular nucleus of patients with Alzheimer's disease. Neurosci Lett 177(1-2): 11-4 (1994).
    • (1994) Neurosci Lett , vol.177 , Issue.1-2 , pp. 11-14
    • Ransmayr, G.1    Benesch, H.2    Nowakowski, C.3    Künig, G.4    Heinsen, H.5    Riederer, P.6
  • 25
    • 68149169022 scopus 로고    scopus 로고
    • Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease
    • Overk CR, Kelley CM, Mufson EJ. Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease. Neurobiol Dis 35(3): 415-25 (2009).
    • (2009) Neurobiol Dis , vol.35 , Issue.3 , pp. 415-425
    • Overk, C.R.1    Kelley, C.M.2    Mufson, E.J.3
  • 26
    • 27644450442 scopus 로고    scopus 로고
    • Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans
    • Brandt T, Schautzer F, Hamilton D, Brüning R, Markowitsch HJ, Kalla R, et al. Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans. Brain 128: 2732-41 (2005).
    • (2005) Brain , vol.128 , pp. 2732-2741
    • Brandt, T.1    Schautzer, F.2    Hamilton, D.3    Brüning, R.4    Markowitsch, H.J.5    Kalla, R.6
  • 28
    • 1542358129 scopus 로고    scopus 로고
    • Cognitive influences in postural control of patients with unilateral vestibular loss
    • Redfern M, Talkowski J, Jennings J, Furman J. Cognitive influences in postural control of patients with unilateral vestibular loss. Gait and Posture 19: 105-14 (2004).
    • (2004) Gait and Posture , vol.19 , pp. 105-114
    • Redfern, M.1    Talkowski, J.2    Jennings, J.3    Furman, J.4
  • 29
    • 77957223307 scopus 로고    scopus 로고
    • Evidence that spatial memory deficits in rats following bilateral vestibular loss are probably permanent
    • Baek J-H, Zheng Y, Darlington CL, Smith PF. Evidence that spatial memory deficits in rats following bilateral vestibular loss are probably permanent. Neurobiol. Learn Mem 94: 402-13 (2010).
    • (2010) Neurobiol. Learn Mem , vol.94 , pp. 402-413
    • Baek, J.-H.1    Zheng, Y.2    Darlington, C.L.3    Smith, P.F.4
  • 30
    • 0025574124 scopus 로고
    • Dyscalculia in patients with vertigo
    • Risey J, Briner W. Dyscalculia in patients with vertigo. J Vestib Res 1: 31-7 (1990-1991)
    • (1990) J Vestib Res , vol.1 , pp. 31-37
    • Risey, J.1    Briner, W.2
  • 31
    • 0344394476 scopus 로고    scopus 로고
    • Bilateral peripheral vestibular lesions produce long-term changes in spatial learning in the rat
    • Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Bilateral peripheral vestibular lesions produce long-term changes in spatial learning in the rat. J Vestib Res 13: 9-16 (2003).
    • (2003) J Vestib Res , vol.13 , pp. 9-16
    • Russell, N.A.1    Horii, A.2    Smith, P.F.3    Darlington, C.L.4    Bilkey, D.K.5
  • 34
    • 0037111844 scopus 로고    scopus 로고
    • Vestibular information is required for dead reckoning in the rat
    • Wallace DG, Hines DJ, Pellis SM, Whishaw IQ. Vestibular information is required for dead reckoning in the rat. J Neurosci 22: 10009-17 (2002).
    • (2002) J Neurosci , vol.22 , pp. 10009-10017
    • Wallace, D.G.1    Hines, D.J.2    Pellis, S.M.3    Whishaw, I.Q.4
  • 35
    • 33744493400 scopus 로고    scopus 로고
    • Impairment and recovery on a food foraging task following unilateral vestibular deafferentation in rats
    • Zheng Y, Darlington CL, Smith PF. Impairment and recovery on a food foraging task following unilateral vestibular deafferentation in rats. Hippocampus 16: 368-78 (2006).
    • (2006) Hippocampus , vol.16 , pp. 368-378
    • Zheng, Y.1    Darlington, C.L.2    Smith, P.F.3
  • 36
    • 34247544940 scopus 로고    scopus 로고
    • Bilateral vestibular deafferentation impairs performance in a spatial forced alternation task in rats
    • Zheng Y, Goddard M, Darlington CL, Smith PF. Bilateral vestibular deafferentation impairs performance in a spatial forced alternation task in rats. Hippocampus 17: 253-56 (2007).
    • (2007) Hippocampus , vol.17 , pp. 253-256
    • Zheng, Y.1    Goddard, M.2    Darlington, C.L.3    Smith, P.F.4
  • 37
    • 65949084258 scopus 로고    scopus 로고
    • Long-term deficits on a foraging task after bilateral vestibular deafferentation in rats
    • Zheng Y, Goddard M, Darlington CL, Smith PF. Long-term deficits on a foraging task after bilateral vestibular deafferentation in rats. Hippocampus. 19: 480-86 (2009).
    • (2009) Hippocampus , vol.19 , pp. 480-486
    • Zheng, Y.1    Goddard, M.2    Darlington, C.L.3    Smith, P.F.4
  • 38
    • 4444358206 scopus 로고    scopus 로고
    • Bilateral labyrinthectomy causes long-term deficits in object recognition in rat
    • Zheng Y, Darlington CL, Smith PF. Bilateral labyrinthectomy causes long-term deficits in object recognition in rat. NeuroReport 15:1913-16 (2004).
    • (2004) NeuroReport , vol.15 , pp. 1913-1916
    • Zheng, Y.1    Darlington, C.L.2    Smith, P.F.3
  • 39
    • 0035986250 scopus 로고    scopus 로고
    • Hippocampal spatial representations require vestibular input
    • Stackman RW, Clark AS, Taube JS. Hippocampal spatial representations require vestibular input. Hippocampus 12: 291-303 (2002).
    • (2002) Hippocampus , vol.12 , pp. 291-303
    • Stackman, R.W.1    Clark, A.S.2    Taube, J.S.3
  • 40
    • 0041342032 scopus 로고    scopus 로고
    • Longterm effects of permanent vestibular lesions on hippocampal spatial firing
    • Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Longterm effects of permanent vestibular lesions on hippocampal spatial firing. J Neurosci 23: 6490-98 (2003).
    • (2003) J Neurosci , vol.23 , pp. 6490-6498
    • Russell, N.A.1    Horii, A.2    Smith, P.F.3    Darlington, C.L.4    Bilkey, D.K.5
  • 42
    • 43449129155 scopus 로고    scopus 로고
    • Locomotor and exploratory behaviour in the rat following bilateral vestibular deafferentation
    • Goddard M, Zheng Y, Darlington CL, Smith PF. Locomotor and exploratory behaviour in the rat following bilateral vestibular deafferentation. Behav Neurosci 122: 448-459 (2008).
    • (2008) Behav Neurosci , vol.122 , pp. 448-459
    • Goddard, M.1    Zheng, Y.2    Darlington, C.L.3    Smith, P.F.4
  • 43
    • 0003516768 scopus 로고    scopus 로고
    • Mathematical statistics and data analysis
    • Duxbury, USA
    • Rice J. Mathematical statistics and data analysis: Duxbury, USA (2007).
    • (2007)
    • Rice, J.1
  • 44
    • 34848906857 scopus 로고    scopus 로고
    • Ampakine (CX717) effects on performance and alertness during simulated night shift work
    • Wesensten NJ, Reichardt RM, Balkin TJ. Ampakine (CX717) effects on performance and alertness during simulated night shift work. Aviat Space Environ Med 78(10): 937-43 (2007).
    • (2007) Aviat Space Environ Med , vol.78 , Issue.10 , pp. 937-943
    • Wesensten, N.J.1    Reichardt, R.M.2    Balkin, T.J.3


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