Preparation of itraconazole-loaded liposomes coated by carboxymethyl chitosan and its pharmacokinetics and tissue distribution

Drug Delivery

Volumn 18, Issue 8, 2011, Pages 631-638

  Wang, Jinping ^a   Huang, Guihua ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Antifungal test; Biodistribution; Carboxymethyl chitosan (CMC); Itraconazole (ITZ); Liposomes; Pharmacokinetics

Indexed keywords

CARBOXYMETHYL CHITOSAN; CHITOSAN DERIVATIVE; ITRACONAZOLE; LIPOSOME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG COATING; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG TISSUE LEVEL; ENCAPSULATION; FEMALE; FILM; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL DELIVERY; LUNG; MALE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TARGET ORGAN; ZETA POTENTIAL;

AMINES; ANIMALS; AREA UNDER CURVE; BRAIN; CANDIDA ALBICANS; CHITOSAN; CHOLESTEROL; DRUG CARRIERS; DRUG STABILITY; FEMALE; ITRACONAZOLE; KIDNEY; LECITHINS; LIPOSOMES; LIVER; LUNG; MALE; MICE; MICE, INBRED STRAINS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCARDIUM; PARTICLE SIZE; PLASMA; SPLEEN; STATIC ELECTRICITY; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 82055176882     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2011.621988     Document Type: Article

References (22)

1. Ascioglu, S., Rex, J. H., de Pauw, B., Bennett, J. E. , Bille, J. , Crokaert, F., Denning, D. W., Donnelly, J. P., Edwards, J. E. , Erjavec, Z., Fiere, D., Lortholary, O., Maertens, J., Meis, J. F. , Patterson, T. F. , Ritter, J., Selleslag, D., Shah, P. M., Stevens, D. A., Walsh, T. J. (2002). De?ning opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An International consensus. Clin Infect Dis. 34:7-14. (Pubitemid 33152659)
2. Bakker-Woudenberg, I.A.J.M. (2002). Long-circulating sterically stabilized liposomes as carriers of agents for treatment of infection or for imaging infectious foci. Int J Antimicrobial Agents. 19:299-311. (Pubitemid 34308978)
3. Banerjee, R. (2001). Liposomes: Applications in Medicine. J Biomater Appl. 16:3-21. (Pubitemid 32715434)
4. Compas, D., Touw, D.J., Goede, P.N. (1996). Rapid method for the analysis of itraconazole and hydroxyitraconazole in serum by high-performance liquid chromatography. J Chrom B Biomed Appl. 687:453-5.
5. Filipovic-Grcic, J., Skalko-Basnet, N., Jalsenjak, I. (2001). Mucoadhesive chitosan-coated liposomes: Characteristics and stability. J Microencapsul. 18:3-12. (Pubitemid 32058676)
6. Gong, G., Xu, S., Xiang, Q., Duan, X.. (2003). Yeast infection in intensive care units: An analysis and survey. Chin J Nosocomiol. 13:282-3.
7. Grant, S., Clissold, S. (1989). ITR: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in super?cial and systemic mycoses. Drugs. 37:310-4.
8. Gregoriadis, G. (1988). Liposomes as drug carriers. Recent trend and progress. New York: John Wiley & Sons.
9. Huang, G.H., Zhu, X.L., Zhang, N., Zhang, B.J. (2007). Preparation of lomustine thermo-sensitive liposomes and investigation of antitumor activity in vitro. Chin Pharm J. 42:914-8. (Pubitemid 47066189)
10. Jain, S., Sehgal, V. (2001). ITR: An effective oral antifungal for onchyomychosis. Int J Dermatol. 40:1-5. (Pubitemid 32201221)
11. Kauffman, C.A., Carver, P.L. (1997). Antifungal agents in the 1990s: Current status and future development. Drugs. 53:539-49. (Pubitemid 27145951)
12. Khatri, J., Qassim, S., Abed, O., Abraham, B., Al-Lami, A., Masood, S. (2001). A novel extractionless HPLC fluorescence method for the determination of glyburide in the human plasma:application to a bioequivalence study. J Pharm Sci. 4:201-3.
13. Kim, J.K., Park, J.S., Kim, C.K. (2010). Development of a binary lipid nanoparticles formulation of itraconazole for parenteral administration and controlled release. Int J Pharm. 383:209-15.
14. Muzzarelli, R.A.A. (1988). Carboxymethylated chitins and chitosans. Carbohydr Polym. 8:l-21.
15. Takeuchi, H., Yamamoto, H., Nina, T., Hino, T., Kawashlma, Y. (1994). Mucoadhesion of polymer-coated liposomes to rat intestine in vitro. Chem Pharm Bull. 42:1954-6. (Pubitemid 24315522)
16. Peeters, J., Neeskens, P., Tollenaere, J.P., Van Remoortere, P., Brewster, M.E. (2002). Characterization of the interaction of 2-hydroxypropylbeta-cyclodextrin with itraconazole at pH 2, 4 and 7. J Pharm Sci. 91:1414-22.
17. Walsh PM. (2003) . Physicians desk reference[M], 57ed, Montvale NJ: Thomson PDR, 1794-1797.
18. Wayne, P.A. (1997). National Committee for Clinical Laboratory Standards, reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard. NCCLS document M27-A. Wayne, Pennsylvania National Committee for Clinical Laboratory Standards.
19. Wu, X.Z., Cheng, A.X., Sun, L.M., Sun, S.J., Lou, H.X. (2009). Plagiochin E, an antifungal bis(bibenzyl), exerts its antifungal activity through mitochondrial dysfunction-induced reactive oxygen species accumulation in Candida albicans. Biochim Biophys Acta. 1790:770-7.
20. Xu, J., Yang, Zh Q., Pan, P., Zhang, X.N., Wu, H.S.H. (2008). Studies on preparation and releasing of cyclosporin a liposome in vitro. Ant Inf Pharm. 5:222-5.
21. Yi, Y., Yoon, H.J., Kim, B.O., Shim, M., Kim, S., Hwang, S., Seo, M.H. (2007). A mixed polymeric micellar for mulation of itraconazole. Characteristics, toxicity and phammcokinetics[J]. J Contr Rel. 117:59-67. (Pubitemid 46161866)
22. Zhang, X., Hou, X. (2003). Comparative efficacy and distribution of Evans blue liposome modified with DSPE 2PEG, Tween80, and Brij35. J Chin Pharm Sci. 12:71-5.