Effect of pluronic P123 and F127 block copolymer on P-glycoprotein transport and CYP3A metabolism

Archives of Pharmacal Research

Volumn 34, Issue 10, 2011, Pages 1719-1728

  Guan, Yanbin ^a   Huang, Jiangeng ^a   Zuo, Lan ^a   Xu, Jiaqiang ^a   Si, Luqin ^a   Qiu, Jun ^a   Li, Gao ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Caco 2; CYP3A; Everted gut sac; P glycoprotein; Pluronic F127; Pluronic P123

Indexed keywords

CYTOCHROME P450 3A; GLYCOPROTEIN P; MIDAZOLAM; POLOXAMER; RHODAMINE 123;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG METABOLISM; HUMAN; HUMAN CELL; ILEUM; INTESTINE MUCOSA; MALE; MICROSOME; NONHUMAN; RAT; SEROSA;

ALGORITHMS; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CACO-2 CELLS; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLORING AGENTS; CYTOCHROME P-450 CYP3A; HUMANS; ILEUM; INTESTINES; MALE; MICROSOMES; MIDAZOLAM; P-GLYCOPROTEIN; POLOXALENE; POLOXAMER; RATS; RHODAMINE 123; TETRAZOLIUM SALTS; THIAZOLES;

EID: 82055176072     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-1016-0     Document Type: Article

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