Plasma gelsolin levels and 1-year mortality after first-ever ischemic stroke

Journal of Critical Care

Volumn 26, Issue 6, 2011, Pages 608-612

  Guo, Xi Chao ^a   Luo, Ben Yan ^a   Li, Xue Fen ^a   Yang, Da Gan ^a   Zheng, Xu Nin ^a   Zhang, Kan ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Gelsolin; Ischemic stroke; Mortality; Prognosis

Indexed keywords

C REACTIVE PROTEIN; GELSOLIN;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PREDICTION; PREDICTIVE VALUE; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SENSITIVITY AND SPECIFICITY;

AGED; AGED, 80 AND OVER; AREA UNDER CURVE; BRAIN ISCHEMIA; CASE-CONTROL STUDIES; CHINA; FEMALE; GELSOLIN; HUMANS; INTENSIVE CARE; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STROKE; SURVIVAL ANALYSIS;

EID: 81955161251     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2011.02.007     Document Type: Article

References (25)

1. Lee W.M., Galbraith R.M. The extracellular actin-scavenger system and actin toxicity. N Engl J Med 1992, 326:1335-1341.
2. Ito H., Kambe H., Kimura Y., et al. Depression of plasma gelsolin level during acute liver injury. Gastroenterology 1992, 102:1686-1692.
3. Lind S.E., Smith D.B., Janmey P.A., et al. Depression of gelsolin levels and detection of gelsolin-actin complexes in plasma of patients with acute lung injury. Am Rev Respir Dis 1988, 138:429-434.
4. Smith D.B., Janmey P.A., Sherwood J.A., et al. Decreased plasma gelsolin levels in patients with Plasmodium falciparum malaria: a consequence of hemolysis?. Blood 1988, 72:214-218.
5. Suhler E., Lin W., Yin H.L., et al. Decreased plasma gelsolin concentrations in acute liver failure, myocardial infarction, septic shock, and myonecrosis. Crit Care Med 1997, 25:594-598.
6. DiNubile M.J., Stossel T.P., Ljunghusen O.C., et al. Prognostic implications of declining plasma gelsolin levels after allogeneic stem cell transplantation. Blood 2002, 100:4367-4371.
7. Lee P.S., Drager L.R., Stossel T.P., et al. Relationship of plasma gelsolin levels to outcomes in critically ill surgical patients. Ann Surg 2006, 243:399-403.
8. Mounzer K.C., Moncure M., Smith Y.R., et al. Relationship of admission plasma gelsolin levels to clinical outcomes in patients after major trauma. Am J Respir Crit Care Med 1999, 160:1673-1681.
9. Osborn T.M., Dahlgren C., Hartwig J.H., et al. Modifications of cellular responses to lysophosphatidic acid and platelet-activating factor by plasma gelsolin. Am J Physiol Cell Physiol 2007, 292:C1323-C1330.
10. Endres M., Fink K., Zhu J., et al. Neuroprotective effects of gelsolin during murine stroke. J Clin Invest 1999, 103:347-351.
11. Güntert A., Campbell J., Saleem M., et al. Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease. J Alzheimers Dis 2010, 21:585-596.
12. Yin H.L., Stossel T.P. Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature 1979, 281:583-586.
13. Kwiatkowski D.J., Stossel T.P., Orkin S.H., et al. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin binding domain. Nature 1986, 323:455-458.
14. Janmey P.A., Lind S.E. Capacity of human serum to depolymerize actin filaments. Blood 1987, 70:524-530.
15. Kwiatkowski D.J., Mehl R., Izumo S., et al. Muscle is the major source of plasma gelsolin. J Biol Chem 1988, 263:8239-8243.
16. Lind S.E., Smith D.B., Janmey P.A., et al. Role of plasma gelsolin and the vitamin D-binding protein in clearing actin from the circulation. J Clin Invest 1986, 78:736-742.
17. Haddad J.G., Harper K.D., Guoth M., et al. Angiopathic consequences of saturating the plasma scavenger system for actin. Proc Natl Acad Sci U S A 1990, 87:1381-1385.
18. Rosengart M.R., Arbabi S., Bauer G.J., et al. The actin cytoskeleton: an essential component for enhanced TNFalpha production by adherent monocytes. Shock 2002, 17:109-113.
19. Huang S., Rhoads S.L., DiNubile M.J. Temporal association between serum gelsolin levels and clinical events in a patient with severe falciparum malaria. Clin Infect Dis 1997, 24:951-954.
20. Bucki R., Georges P.C., Espinassous Q., et al. Inactivation of endotoxin by human plasma gelsolin. Biochemistry 2005, 44:9590-9597.
21. Goetzl E.J., Lee H., Azuma T., et al. Gelsolin binding and cellular presentation of lysophosphatidic acid. J Biol Chem 2000, 275:14573-14578.
22. Lee P.S., Waxman A.B., Cotich K.L., et al. Plasma gelsolin is a marker and therapeutic agent in animal sepsis. Crit Care Med 2007, 35:849-855.
23. Christofidou-Solomidou M., Scherpereel A., Solomides C.C., et al. Recombinant plasma gelsolin diminishes the acute inflammatory response to hyperoxia in mice. J Investig Med 2002, 50:54-60.
24. Rothenbach P.A., Dahl B., Schwartz J.J., et al. Recombinant plasma gelsolin infusion attenuates burn-induced pulmonary microvascular dysfunction. J Appl Physiol 2004, 96:25-31.
25. Yildirim F., Gertz K., Kronenberg G., et al. Inhibition of histone deacetylation protects wild type but not gelsolin-deficient mice from ischemic brain injury. Exp Neurol 2008, 210:531-542.