Functional properties and substrate characterization of human CYP26A1, CYP26B1, and CYP26C1 expressed by recombinant baculovirus in insect cells

Journal of Pharmacological and Toxicological Methods

Volumn 64, Issue 3, 2011, Pages 258-263

  Helvig, Christian ^a   Taimi, Mohammed ^a   Cameron, Don ^b,c   Jones, Glenville ^b   Petkovich, Martin ^a,b,c  

^a Cytochroma Inc   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c QUEEN S UNIVERSITY   (Canada)

Author keywords

Assay; Baculovirus; CYP26; Metabolism; Retinoic Acid

Indexed keywords

CYP26B1 PROTEIN; CYP26C1 PROTEIN; CYTOCHROME P450; CYTOCHROME P450 26A1; RETINOIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BINDING ASSAY; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME SUBSTRATE; IN VITRO STUDY; INSECT CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; BACULOVIRIDAE; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INSECTS; ISOENZYMES; MICROSOMES; NADP; OXIDOREDUCTASES; PROTEIN BINDING; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TRETINOIN;

HEXAPODA;

EID: 81955160686     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2011.08.005     Document Type: Article

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