Potassium bromate (KBrO3) induced nephrotoxicity: Protective effects of n-hexane extract of Sonchus asper

Journal of Medicinal Plant Research

Volumn 5, Issue 25, 2011, Pages 6055-6060

  Khan, Rahmat Ali ^a   Khan, Muhammad Rashid ^b   Sahreen, Sumaira ^b   Shah, Nasir Ali ^b   Bokhari, Jasia ^b   Shabbir, Maria ^b   Rashid, Umbreen ^b   Jan, Shumila ^b  

^a Department of Biotechnology   (Pakistan)

^b QUAID I AZAM UNIVERSITY   (Pakistan)

Author keywords

Antioxidant enzymes; Argyrophilic nucleolar organiser regions (agnors); Dna fragmentation; Sonchus asper; Telomerase enzyme inhibition

Indexed keywords

PLANT EXTRACT; POTASSIUM BROMATE; PROTECTIVE AGENT; SONCHUS ASPER EXTRACT; TELOMERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; LIPID PEROXIDATION; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; SONCHUS; SONCHUS ASPER;

EID: 81855226127     PISSN: None     EISSN: 19960875     Source Type: Journal    
DOI: 10.5897/JMPR11.987     Document Type: Article

References (25)

1. Castello MC, Phatak A, Chandra N, Sharon M (2002). Antimicrobial activity of crude extracts from plant parts and corresponding calli of Bixa orellana L. Indian J. Exp. Biol., 1378-1381
2. Carlberg I, Mannervik EB (1975). Glutathione level in rat brain. J. Biol. Chem., 250: 4475-4480
3. Chance B, Maehly AC (1955). Assay of catalase and peroxidases. Met. Enzymol., 11: 764-775
4. Habig WH, Pabst MJ, Jakoby WB (1974). Glutathione-S-transferases: the first enzymatic step in mercapturic acid formation. J. Biol. Chem., 249: 7130-7139
5. Hill AF (1952). Economic Botany. A textbook of useful plants and plant products. 2nd edn. McGraw-Hill Book Company Inc, New York.
6. Irazusta SP, Vassallo J, Magna LA (1998). The value of PCNA and AgNOR staining in endoscopic biopsies of gastric mucosa. Pathol. Res. Prac., 194: 33-39
7. Iqbal M, Sharma SD, Zadeh HR, Hasan N, Abdulla M, Athar M (1996). Glutathione metabolizing enzymes and oxidative stress in ferric nitrilotriacetate (Fe-NTA) mediated hepatic injury. Redox Report, 2: 385-391
8. Jollow DJ, Mitchell JR, Zampaglione N, Gillete JR (1974). Bromobenzene induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as a hepatotoxic metabolite. Pharmacology, 11: 151-169
9. Kakkar P, Das B, Viswanathan PN (1984). A modified spectrophotometric assay of superoxide dimutase. Indian J. Biochem. Biophys., 21: 130-132
10. Khan MR, Haroon J, Khan RA, Bokhari J, Rashid U (2011). Prevention of KBrO3-induced cardiotoxicity by Sonchus asper in rat. J. Med. Plants Res., 5(12): 2514-2520
11. Khan MR, Rizvi W, Khan GN, Khan RA, Sheen S (2009). Carbon tetrachloride-induced nephrotoxicity in rats: Protective role of Digera muricata. J. Ethnopharmacol., 122: 91-99
12. Khan N, Sultana S (2005). Chemomodulatory effect of Ficus racemosa extract against chemically induced renal carcinogenesis and oxidative damage response in Wister rats. Life Sci., 77: 1194-1210
13. Khan RA, Khan MR, Sahreen S (2010a). Evaluation of Launea procumbens use in renal disorders: a rat model. J. Ethnopharmacol., 128: 452-461
14. Khan RA, Khan MR, Sahreen S (2011a). Protective effect of Sonchus asper extracts against experimentally-induced lung injuries in rats: A novel study. Exp. Toxicol. Pathol. doi:10.1016/j.etp.2011.01.007.
15. Khan RA, Khan MR, Sahreen S, Bukhari J (2010b). Prevention of CCl4-induced nephrotoxicity with Sonchus asper in rat. Food Chem. Toxicol., 23: 1304-1321
16. Khan RA, Khan MR, Sahreen S, Bukhari J (2010c). Antimicrobial and Phytotoxic activity of various fractions of Sonchus asper. Afr. J. Biotechnol., 47: 3877-3683
17. Khan RA, Khan MR, Sahreen S, Jan S, Bokhari J, Rashid U (2011b). Phytotoxic characterization of various fractions of Launaeaprocumbens. Afr. J. Biotechnol., 10: 5377-5380
18. Mohandas J, Marshal JJ, Duggin GG, Horvath JS, Tiller DJ (1984). Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney. Possible implications in analgesic nephropathy. Biochem. Pharmacol., 33: 1801-1807
19. Ramachandran C, Fonseca HB, Jhabvala P, Escalon EA, Melnick SJ (2002). Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line. Cancer Lett., 184: 1-6
20. Sahreen S, Khan MR, Khan RA (2010). Evaluation of antioxidant activities of various solvent extracts of Carissa opaca fruits. Food Chem., 122: 1205-1211
21. Sahreen S, Khan MR, Khan RA (2011). Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat. BMC Compl. Alter. Med., 11:48 doi: 10.1186/1472-6882-11-48
22. Tona L, Kambu K, Ngimbi N, Mesia K, Penge O, Lusakibanza M, Cimanga K, De BT, Apers S, Totte J, Pieters L, Vlietinck AJ (2000). Antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in Kinshasa, Congo. Phytomedicine, 7: 31-38
23. Trere D, Zilbering A, Dittus D, Kim P, Ginsberg PC, Daskal I (1996). AgNOR quantity in needle biopsy specimens of prostatic adenocarcinomas: correlation with proliferation state, Gleason score, clinical stage, and DNA content. J. Clin. Pathol., 49: 209-213
24. Wilkinson EJ (1990). Vulvar intraepithelial neoplasia and squamous cell carcinoma with Sofowara emphasis on new nomenclature. Prog. Reprod. Urin. Tract Pathol., 2: 1-20
25. Wu B, Ootani A, Iwakiri R, Sakata Y, Fujise T, Amemori S, Yokoyama F, Tsunada S, Fujimoto K (2005). T cell deficiency leads to liver carcinogenesis in Azoxymethane-treated rats. Exp. Biol. Med., 231: 91-98.