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Volumn 115, Issue 6, 2011, Pages 1239-1250

Metabotropic glutamate receptor 5 antagonism with fenobam: Examination of analgesic tolerance and side effect profile in mice

Author keywords

[No Author keywords available]

Indexed keywords

FENOBAM; METABOTROPIC RECEPTOR 5;

EID: 81855221702     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e318238c051     Document Type: Article
Times cited : (18)

References (30)
  • 1
    • 77949516412 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Physiology, pharmacology, and disease
    • Niswender CM, Conn PJ: Metabotropic glutamate receptors: Physiology, pharmacology, and disease. Annu Rev Pharmacol Toxicol 2010; 50:295-322
    • (2010) Annu Rev Pharmacol Toxicol , vol.50 , pp. 295-322
    • Niswender, C.M.1    Conn, P.J.2
  • 2
    • 0345830631 scopus 로고    scopus 로고
    • Physiological roles and therapeutic potential of metabotropic glutamate receptors
    • Conn PJ: Physiological roles and therapeutic potential of metabotropic glutamate receptors. Ann N Y Acad Sci 2003; 1003:12-21
    • (2003) Ann N y Acad Sci , vol.1003 , pp. 12-21
    • Conn, P.J.1
  • 3
    • 0001050064 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor involvement in models of acute and persistent pain: Prospects for the development of novel analgesics
    • Varney MA, Gereau RW: Metabotropic glutamate receptor involvement in models of acute and persistent pain: Prospects for the development of novel analgesics. Curr Drug Target CNS Neurol Disord 2002; 1:283-96
    • (2002) Curr Drug Target CNS Neurol Disord , vol.1 , pp. 283-296
    • Varney, M.A.1    Gereau, R.W.2
  • 6
    • 0035094199 scopus 로고    scopus 로고
    • Peripheral group i metabotropic glutamate receptors modulate nociception in mice
    • Bhave G, Karim F, Carlton SM, Gereau RW 4th: Peripheral group I metabotropic glutamate receptors modulate nociception in mice. Nat Neurosci 2001; 4:417-23
    • (2001) Nat Neurosci , vol.4 , pp. 417-423
    • Bhave, G.1    Karim, F.2    Carlton, S.M.3    Gereau, I.V.R.W.4
  • 7
    • 0035371317 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice
    • Karim F, Wang CC, Gereau RW 4th: Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice. J Neurosci 2001; 21:3771-9
    • (2001) J Neurosci , vol.21 , pp. 3771-3779
    • Karim, F.1    Wang, C.C.2    Gereau, I.V.R.W.3
  • 12
    • 77952473377 scopus 로고    scopus 로고
    • Glutamatergic fine tuning with ADX-10059: A novel therapeutic approach for migraine?
    • Marin JC, Goadsby PJ: Glutamatergic fine tuning with ADX-10059: A novel therapeutic approach for migraine? Expert Opin Investig Drugs 2010; 19:555-61
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 555-561
    • Marin, J.C.1    Goadsby, P.J.2
  • 15
    • 0019957859 scopus 로고
    • Treatment of anxiety using fenobam (a nonbenzodiazepine) in a double-blind standard (diazepam) placebo-controlled study
    • Pecknold JC, McClure DJ, Appeltauer L, Wrzesinski L, Allan T: Treatment of anxiety using fenobam (a nonbenzodiazepine) in a double-blind standard (diazepam) placebo-controlled study. J Clin Psychopharmacol 1982; 2:129-33
    • (1982) J Clin Psychopharmacol , vol.2 , pp. 129-133
    • Pecknold, J.C.1    McClure, D.J.2    Appeltauer, L.3    Wrzesinski, L.4    Allan, T.5
  • 16
    • 0018877483 scopus 로고
    • Phase II double blind controlled study of a new anxiolytic, fenobam (McN-3377) versus placebo
    • Friedmann CTH, Davis LJ, Ciccone PE, Rubin RT: Phase II double blind controlled study of a new anxiolytic, fenobam (McN-3377) versus placebo. Curr Ther Res 1980; 27:144-51
    • (1980) Curr Ther Res , vol.27 , pp. 144-151
    • Friedmann, C.T.H.1    Davis, L.J.2    Ciccone, P.E.3    Rubin, R.T.4
  • 17
    • 0020032357 scopus 로고
    • Fenobam: Another anxiolytic?
    • Lapierre Y, Oyewumi L: Fenobam: Another anxiolytic? Curr Ther Res 1982; 31:95-101
    • (1982) Curr Ther Res , vol.31 , pp. 95-101
    • Lapierre, Y.1    Oyewumi, L.2
  • 19
    • 64849110971 scopus 로고    scopus 로고
    • MGluR5 has a critical role in inhibitory learning
    • Xu J, Zhu Y, Contractor A, Heinemann SF: mGluR5 has a critical role in inhibitory learning. J Neurosci 2009; 29: 3676-84
    • (2009) J Neurosci , vol.29 , pp. 3676-3684
    • Xu, J.1    Zhu, Y.2    Contractor, A.3    Heinemann, S.F.4
  • 21
    • 77249152214 scopus 로고    scopus 로고
    • Transient early-life forebrain corticotropin-releasing hormone elevation causes longlasting anxiogenic and despair-like changes in mice
    • Kolber BJ, Boyle MP, Wieczorek L, Kelley CL, Onwuzurike CC, Nettles SA, Vogt SK, Muglia LJ: Transient early-life forebrain corticotropin-releasing hormone elevation causes longlasting anxiogenic and despair-like changes in mice. J Neurosci 2010; 30:2571-81
    • (2010) J Neurosci , vol.30 , pp. 2571-2581
    • Kolber, B.J.1    Boyle, M.P.2    Wieczorek, L.3    Kelley, C.L.4    Onwuzurike, C.C.5    Nettles, S.A.6    Vogt, S.K.7    Muglia, L.J.8
  • 22
    • 9644268904 scopus 로고    scopus 로고
    • Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults
    • Wozniak DF, Hartman RE, Boyle MP, Vogt SK, Brooks AR, Tenkova T, Young C, Olney JW, Muglia LJ: Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults. Neurobiol Dis 2004; 17:403-14
    • (2004) Neurobiol Dis , vol.17 , pp. 403-414
    • Wozniak, D.F.1    Hartman, R.E.2    Boyle, M.P.3    Vogt, S.K.4    Brooks, A.R.5    Tenkova, T.6    Young, C.7    Olney, J.W.8    Muglia, L.J.9
  • 23
    • 0034693328 scopus 로고    scopus 로고
    • Effects of the prototypical mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats
    • Spooren WP, Gasparini F, Bergmann R, Kuhn R: Effects of the prototypical mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats. Eur J Pharmacol 2000; 406:403-10
    • (2000) Eur J Pharmacol , vol.406 , pp. 403-410
    • Spooren, W.P.1    Gasparini, F.2    Bergmann, R.3    Kuhn, R.4
  • 24
    • 33747036934 scopus 로고    scopus 로고
    • Analgesic effects of mGlu1 and mGlu5 receptor antagonists in the rat formalin test
    • Sevostianova N, Danysz W: Analgesic effects of mGlu1 and mGlu5 receptor antagonists in the rat formalin test. Neuropharmacology 2006; 51:623-30
    • (2006) Neuropharmacology , vol.51 , pp. 623-630
    • Sevostianova, N.1    Danysz, W.2
  • 26
    • 0034892735 scopus 로고    scopus 로고
    • Weight loss and exercise walking reduce pain and improve physical functioning in overweight postmenopausal women with knee osteoarthritis
    • Martin K, Fontaine KR, Nicklas BJ, Dennis KE, Goldberg AP, Hochberg MC: Weight loss and exercise walking reduce pain and improve physical functioning in overweight postmenopausal women with knee osteoarthritis. J Clin Rheumatol 2001; 7:219-23
    • (2001) J Clin Rheumatol , vol.7 , pp. 219-223
    • Martin, K.1    Fontaine, K.R.2    Nicklas, B.J.3    Dennis, K.E.4    Goldberg, A.P.5    Hochberg, M.C.6
  • 27
    • 79952787066 scopus 로고    scopus 로고
    • Randomised clinical trial: Effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease
    • Zerbib F, Bruley des Varannes S, Roman S, Tutuian R, Galmiche JP, Mion F, Tack J, Malfertheiner P, Keywood C: Randomised clinical trial: Effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2011; 33:911-21
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 911-921
    • Zerbib, F.1    Bruley Des Varannes, S.2    Roman, S.3    Tutuian, R.4    Galmiche, J.P.5    Mion, F.6    Tack, J.7    Malfertheiner, P.8    Keywood, C.9
  • 29
    • 0142150242 scopus 로고    scopus 로고
    • Factors contributory to early death of young CD-1 mice in carcinogenicity studies
    • Son WC: Factors contributory to early death of young CD-1 mice in carcinogenicity studies. Toxicol Lett 2003; 145: 88-98
    • (2003) Toxicol Lett , vol.145 , pp. 88-98
    • Son, W.C.1


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