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Volumn 10, Issue 22, 2011, Pages 3830-3833

Targeted cancer therapy: What if the driver is just a messenger?

Author keywords

Cancer; eIF4E; Lymphoma; Targeted therapy; Translation

Indexed keywords

CYCLIN D1; FLAVAGLINE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MYC PROTEIN; PLANT MEDICINAL PRODUCT; PROTEIN KINASE INHIBITOR; PROTEIN KINASE PIM 1; PROTEIN MCL 1; RAPALOG; RNA HELICASE; SGI 1773; SGI 1776; SILVESTROL; UNCLASSIFIED DRUG; VEMURAFENIB;

EID: 81855212716     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.22.18288     Document Type: Review
Times cited : (15)

References (26)
  • 1
    • 79953295145 scopus 로고    scopus 로고
    • Second-generation tyrosine kinase inhibitors: The future of frontline CML therapy
    • PMID:21307148; DOI:10.1158/1078-0432.CCR-10-2922
    • Kantarjian HM, Baccarani M, Jabbour E, Saglio G, Cortes JE. Second-generation tyrosine kinase inhibitors: the future of frontline CML therapy. Clin Cancer Res 2011; 17:1674-83; PMID:21307148; DOI:10.1158/1078-0432. CCR-10-2922.
    • (2011) Clin Cancer Res , vol.17 , pp. 1674-1683
    • Kantarjian, H.M.1    Baccarani, M.2    Jabbour, E.3    Saglio, G.4    Cortes, J.E.5
  • 2
    • 79953326958 scopus 로고    scopus 로고
    • Targeting BRAF in advanced melanoma: A first step toward manageable disease
    • PMID:21447722; DOI:10.1158/1078-0432.CCR-10-0174
    • Vultur A, Villanueva J, Herlyn M. Targeting BRAF in advanced melanoma: a first step toward manageable disease. Clin Cancer Res 2011; 17:1658-63; PMID:21447722; DOI:10.1158/1078-0432.CCR-10-0174.
    • (2011) Clin Cancer Res , vol.17 , pp. 1658-1663
    • Vultur, A.1    Villanueva, J.2    Herlyn, M.3
  • 3
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • PMID:21639808; DOI:10.1056/NEJMoa1103782
    • Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364:2507-16; PMID:21639808; DOI:10.1056/NEJMoa1103782.
    • (2011) N Engl J Med , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3    Haanen, J.B.4    Ascierto, P.5    Larkin, J.6
  • 4
    • 33845444046 scopus 로고    scopus 로고
    • Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
    • PMID:17151364; DOI:10.1056/NEJMoa062867
    • Druker BJ, Guilhot F, O'Brien SG, Gathmann I, Kantarjian H, Gattermann N, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 2006; 355:2408-17; PMID:17151364; DOI:10.1056/ NEJMoa062867.
    • (2006) N Engl J Med , vol.355 , pp. 2408-2417
    • Druker, B.J.1    Guilhot, F.2    O'Brien, S.G.3    Gathmann, I.4    Kantarjian, H.5    Gattermann, N.6
  • 5
    • 49649127657 scopus 로고    scopus 로고
    • Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
    • PMID:18483355; DOI:10.1158/1078-0432.CCR-07-2248
    • Engelman JA, Janne PA. Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. Clin Cancer Res 2008; 14:2895-9; PMID:18483355; DOI:10.1158/1078-0432.CCR-07- 2248.
    • (2008) Clin Cancer Res , vol.14 , pp. 2895-2899
    • Engelman, J.A.1    Janne, P.A.2
  • 6
    • 35548968518 scopus 로고    scopus 로고
    • Cancer: Mixing cocktails
    • PMID:17960228; DOI:10.1038/449993a
    • Sawyers CL. Cancer: mixing cocktails. Nature 2007; 449:993-6; PMID:17960228; DOI:10.1038/449993a.
    • (2007) Nature , vol.449 , pp. 993-996
    • Sawyers, C.L.1
  • 7
    • 79955975429 scopus 로고    scopus 로고
    • Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
    • PMID:21575859; DOI:10.1016/j.ccr.2011.04.008
    • Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell 2011; 19:575-86; PMID:21575859; DOI:10.1016/j.ccr.2011.04.008.
    • (2011) Cancer Cell , vol.19 , pp. 575-586
    • Carver, B.S.1    Chapinski, C.2    Wongvipat, J.3    Hieronymus, H.4    Chen, Y.5    Chandarlapaty, S.6
  • 8
    • 70449529715 scopus 로고    scopus 로고
    • Molecular networks and system-level properties
    • PMID:19616593; DOI:10.1016/j.jbiotec.2009.07.009
    • Alberghina L, Hofer T, Vanoni M. Molecular networks and system-level properties. J Biotechnol 2009; 144:224-33; PMID:19616593; DOI:10.1016/j.jbiotec. 2009.07.009.
    • (2009) J Biotechnol , vol.144 , pp. 224-233
    • Alberghina, L.1    Hofer, T.2    Vanoni, M.3
  • 9
    • 79955637310 scopus 로고    scopus 로고
    • The biological and therapeutic relevance of mRNA translation in cancer. Nature reviews
    • Blagden SP, Willis AE. The biological and therapeutic relevance of mRNA translation in cancer. Nature reviews. Nat Rev Clin Oncol 2011; 8:280-91.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 280-291
    • Blagden, S.P.1    Willis, A.E.2
  • 10
    • 0025314596 scopus 로고
    • Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap
    • PMID:2348862; DOI:10.1038/345544a0
    • Lazaris-Karatzas A, Montine KS, Sonenberg N. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap. Nature 1990; 345:544-7; PMID:2348862; DOI:10.1038/345544a0.
    • (1990) Nature , vol.345 , pp. 544-547
    • Lazaris-Karatzas, A.1    Montine, K.S.2    Sonenberg, N.3
  • 11
    • 1642586272 scopus 로고    scopus 로고
    • Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
    • PMID:15029198; DOI:10.1038/nature02369
    • Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, et al. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 2004; 428:332-7; PMID:15029198; DOI:10.1038/nature02369.
    • (2004) Nature , vol.428 , pp. 332-337
    • Wendel, H.G.1    De Stanchina, E.2    Fridman, J.S.3    Malina, A.4    Ray, S.5    Kogan, S.6
  • 12
    • 77952393003 scopus 로고    scopus 로고
    • Mechanisms governing the control of mRNA translation
    • PMID:20463379; DOI:10.1088/1478-3975/7/2/021001
    • Livingstone M, Atas E, Meller A, Sonenberg N. Mechanisms governing the control of mRNA translation. Phys Biol 2010; 7:21001; PMID:20463379; DOI:10.1088/1478-3975/7/2/021001.
    • (2010) Phys Biol , vol.7 , pp. 21001
    • Livingstone, M.1    Atas, E.2    Meller, A.3    Sonenberg, N.4
  • 13
    • 0027421241 scopus 로고
    • Mechanism of action and regulation of protein synthesis initiation factor 4E: Effects on mRNA discrimination, cellular growth rate and oncogenesis
    • PMID:8234784; DOI:10.1016/S0079-6603(08)61022-3
    • Rhoads RE, Joshi-Barve S, Rinker-Schaeffer C. Mechanism of action and regulation of protein synthesis initiation factor 4E: effects on mRNA discrimination, cellular growth rate and oncogenesis. Prog Nucleic Acid Res Mol Biol 1993; 46:183-219; PMID:8234784; DOI:10.1016/S0079-6603(08)61022-3.
    • (1993) Prog Nucleic Acid Res Mol Biol , vol.46 , pp. 183-219
    • Rhoads, R.E.1    Joshi-Barve, S.2    Rinker-Schaeffer, C.3
  • 14
    • 0037273324 scopus 로고    scopus 로고
    • Translational control and metastatic progression: Enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs
    • PMID:12741684; DOI:10.1023/A:1022943419011
    • Graff JR, Zimmer SG. Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs. Clin Exp Metastasis 2003; 20:265-73; PMID:12741684; DOI:10.1023/A:1022943419011.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 265-273
    • Graff, J.R.1    Zimmer, S.G.2
  • 15
    • 37249042829 scopus 로고    scopus 로고
    • Dissecting eIF4E action in tumorigenesis
    • PMID:18055695; DOI:10.1101/gad.1604407
    • Wendel HG, Silva RL, Malina A, Mills JR, Zhu H, Ueda T, et al. Dissecting eIF4E action in tumorigenesis. Genes Dev 2007; 21:3232-7; PMID:18055695; DOI:10.1101/gad.1604407.
    • (2007) Genes Dev , vol.21 , pp. 3232-3237
    • Wendel, H.G.1    Silva, R.L.2    Malina, A.3    Mills, J.R.4    Zhu, H.5    Ueda, T.6
  • 16
    • 80054845323 scopus 로고    scopus 로고
    • Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
    • PMID:21859846; DOI:10.1084/jem.20110846
    • Schatz JH, Oricchio E, Wolfe AL, Jiang M, Linkov I, Maragulia J, et al. Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma. J Exp Med 2011; 208:1799-807; PMID:21859846; DOI:10.1084/jem.20110846.
    • (2011) J Exp Med , vol.208 , pp. 1799-1807
    • Schatz, J.H.1    Oricchio, E.2    Wolfe, A.L.3    Jiang, M.4    Linkov, I.5    Maragulia, J.6
  • 17
    • 0031442452 scopus 로고    scopus 로고
    • Pim-1 protein expression is regulated by its 5'-untranslated region and translation initiation factor elF-4E
    • PMID:9419425
    • Hoover DS, Wingett DG, Zhang J, Reeves R, Magnuson NS. Pim-1 protein expression is regulated by its 5'-untranslated region and translation initiation factor elF-4E. Cell Growth Differ 1997; 8:1371-80; PMID:9419425.
    • (1997) Cell Growth Differ , vol.8 , pp. 1371-1380
    • Hoover, D.S.1    Wingett, D.G.2    Zhang, J.3    Reeves, R.4    Magnuson, N.S.5
  • 18
    • 53349103292 scopus 로고    scopus 로고
    • Modelling Myc inhibition as a cancer therapy
    • PMID:18716624; DOI:10.1038/nature07260
    • Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, et al. Modelling Myc inhibition as a cancer therapy. Nature 2008; 455:679-83; PMID:18716624; DOI:10.1038/nature07260.
    • (2008) Nature , vol.455 , pp. 679-683
    • Soucek, L.1    Whitfield, J.2    Martins, C.P.3    Finch, A.J.4    Murphy, D.J.5    Sodir, N.M.6
  • 19
    • 46749097944 scopus 로고    scopus 로고
    • Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model
    • PMID:18551192
    • Bordeleau ME, Robert F, Gerard B, Lindqvist L, Chen SM, Wendel HG, et al. Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model. J Clin Invest 2008; 118:2651-60; PMID:18551192.
    • (2008) J Clin Invest , vol.118 , pp. 2651-2660
    • Bordeleau, M.E.1    Robert, F.2    Gerard, B.3    Lindqvist, L.4    Chen, S.M.5    Wendel, H.G.6
  • 20
    • 80755139573 scopus 로고    scopus 로고
    • Targeting the PI3K/AKT/mTOR Pathway in Non-Hodgkin's Lymphoma: Results, Biology and Development Strategies
    • PMID:21755275; DOI:10.1007/s11912-011-0187-7
    • Schatz JH. Targeting the PI3K/AKT/mTOR Pathway in Non-Hodgkin's Lymphoma: Results, Biology and Development Strategies. Curr Oncol Rep 2011; 13:398-406; PMID:21755275; DOI:10.1007/s11912-011-0187-7.
    • (2011) Curr Oncol Rep , vol.13 , pp. 398-406
    • Schatz, J.H.1
  • 21
    • 0042626302 scopus 로고    scopus 로고
    • The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor
    • PMID:12869584; DOI:10.1101/gad.1105003
    • Fox CJ, Hammerman PS, Cinalli RM, Master SR, Chodosh LA, Thompson CB. The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. Genes Dev 2003; 17:1841-54; PMID:12869584; DOI:10.1101/gad.1105003.
    • (2003) Genes Dev , vol.17 , pp. 1841-1854
    • Fox, C.J.1    Hammerman, P.S.2    Cinalli, R.M.3    Master, S.R.4    Chodosh, L.A.5    Thompson, C.B.6
  • 22
    • 19344374597 scopus 로고    scopus 로고
    • Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival
    • PMID:15705789; DOI:10.1182/blood-2004-09-3706
    • Hammerman PS, Fox CJ, Birnbaum MJ, Thompson CB. Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. Blood 2005; 105:4477-83; PMID:15705789; DOI:10.1182/blood-2004-09-3706.
    • (2005) Blood , vol.105 , pp. 4477-4483
    • Hammerman, P.S.1    Fox, C.J.2    Birnbaum, M.J.3    Thompson, C.B.4
  • 24
    • 80053558376 scopus 로고    scopus 로고
    • Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells
    • PMID:21962511; DOI:10.1016/j.cell.2011.07.049
    • Chiarle R, Zhang Y, Frock RL, Lewis SM, Molinie B, Ho YJ, et al. Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells. Cell 2011; 147:107-19; PMID:21962511; DOI:10.1016/j.cell.2011.07.049.
    • (2011) Cell , vol.147 , pp. 107-119
    • Chiarle, R.1    Zhang, Y.2    Frock, R.L.3    Lewis, S.M.4    Molinie, B.5    Ho, Y.J.6
  • 25
    • 80053502216 scopus 로고    scopus 로고
    • Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes
    • PMID:21962510; DOI:10.1016/j.cell.2011.07.048
    • Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, et al. Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes. Cell 2011; 147:95-106; PMID:21962510; DOI:10.1016/j.cell.2011.07.048.
    • (2011) Cell , vol.147 , pp. 95-106
    • Klein, I.A.1    Resch, W.2    Jankovic, M.3    Oliveira, T.4    Yamane, A.5    Nakahashi, H.6
  • 26
    • 65549098672 scopus 로고    scopus 로고
    • Antitumor activity and mechanism of action of the cyclopenta[b] benzofuran, silvestrol
    • PMID:19401772; DOI : 10.1371/journal.pone.0005223
    • Cencic R, Carrier M, Galicia-Vazquez G, Bordeleau ME, Sukarieh R, Bourdeau A, et al. Antitumor activity and mechanism of action of the cyclopenta[b] benzofuran, silvestrol. PLoS ONE 2009; 4:5223; PMID:19401772; DOI :10.1371/journal.pone.0005223.
    • (2009) PLoS ONE , vol.4 , pp. 5223
    • Cencic, R.1    Carrier, M.2    Galicia-Vazquez, G.3    Bordeleau, M.E.4    Sukarieh, R.5    Bourdeau, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.