School-aged children who were exposed to sodium valproate in utero have impaired language scores when compared with a population mean score

Evidence-Based Medicine

Volumn 16, Issue 6, 2011, Pages 178-179

  Baker, Gus A ^a   Bromley, Rebecca L ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; LAMOTRIGINE; VALPROIC ACID;

BRAIN DEVELOPMENT; CHILD; CHILD DEVELOPMENT; COGNITIVE DEVELOPMENT; CONGENITAL MALFORMATION; EPILEPSY; HIGH RISK PREGNANCY; HUMAN; INTELLIGENCE QUOTIENT; LANGUAGE DEVELOPMENT; LANGUAGE DISABILITY; MONOTHERAPY; NEUROLOGIC EXAMINATION; NOTE; PLACENTAL TRANSFER; PRENATAL DRUG EXPOSURE; PRESCHOOL CHILD; SCHOOL CHILD; SOCIAL STATUS;

EID: 81855203477     PISSN: 13565524     EISSN: 14736810     Source Type: Journal    
DOI: 10.1136/ebmed-2011-000025     Document Type: Note

References (5)

1. Meador K, Reynolds MW, Crean S, et al. Pregnancy outcomes in women with epilepsy: a systematic review and meta-analysis of published pregnancy registries and cohorts. Epilepsy Res 2008;81:1-13.
2. Meador KJ, Baker GA, Browning N, et al. Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age. Brain 2011;134:396-404.
3. Bromley RL, Mawer G, Love J, et al. Early cognitive development in children born to women with epilepsy: a prospective report. Epilepsia 2010;51:2058-65.
4. Nadebaum C, Anderson V, Vajda F, et al. The Australian brain and cognition and antiepileptic drugs study: IQ in school-aged children exposed to sodium valproate and polytherapy. J Int Neuropsychol Soc 2011;17:133-42.
5. Adab N, Kini U, Vinten J, et al. The longer term outcome of children born to mothers with epilepsy. J Neurol Neurosurg Psychiatr 2004;75:1575-83. (Pubitemid 39430610)