Triptans attenuate capsaicin-induced CREB phosphorylation within the trigeminal nucleus caudalis: A mechanism to prevent central sensitization?

Journal of Headache and Pain

Volumn 12, Issue 4, 2011, Pages 411-417

  Mitsikostas, Dimos D ^a,b   Knight, Yolande E ^a   Lasalandra, Michele ^a   Kavantzas, Nikolaos ^c   Goadsby, Peter J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ATHENS NAVAL HOSPITAL   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Capsaicin; CREB; Migraine; Naratriptan; Sensitization; Sumatriptan

Indexed keywords

CAPSAICIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NARATRIPTAN; SUMATRIPTAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR P CREB; TRIPTAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIZATION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TRANSCRIPTION REGULATION; TRIGEMINAL NUCLEUS; TRIGEMINAL NUCLEUS CAUDALIS;

ANIMALS; CAPSAICIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; MALE; PAIN; PHOSPHORYLATION; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; SENSORY SYSTEM AGENTS; SUMATRIPTAN; TRIGEMINAL CAUDAL NUCLEUS; TRYPTAMINES;

EID: 81855194002     PISSN: 11292369     EISSN: 11292377     Source Type: Journal    
DOI: 10.1007/s10194-011-0352-2     Document Type: Article

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