Study of pseudoternary phase diagram behaviour and the effect of several tweens and spans on palm oil esters characteristics

International Journal of Drug Delivery

Volumn 3, Issue 1, 2011, Pages 95-100

  Abdulkarim, Muthanna F ^a   Abdullah, Ghassan Z ^a   Sakeena, M H F ^a   Chitneni, Mallikarjun ^a   Yam, Mun F ^a,b   Mahdi, Elrashid S ^a   Salman, Ibrahim M ^a   Ameer, Omar Z ^a   Sattar, Munavvar A ^a   Basri, Mahiran ^b   Noor, Azmin M ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

O W emulsion; Palm oil esters; Pseudoternary phase diagram; Span; Tween

Indexed keywords

ESTER DERIVATIVE; NONIONIC SURFACTANT; PALM OIL ESTER; POLYSORBATE 80; SORBITAN LAURATE; UNCLASSIFIED DRUG; BENZOIC ACID; METHYLENE BLUE; PALM OIL ESTER DERIVATIVE; POLYSORBATE 85; SORBITAN TRIOLEATE; WATER;

ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); EMULSION; PHASE TRANSITION; WATER CONTENT; CONDUCTANCE; GEL; MICROEMULSION; PSEUDOTERNARY PHASE DIAGRAM; RACEMIC MIXTURE;

EID: 81855191435     PISSN: None     EISSN: 09750215     Source Type: Journal    
DOI: 10.5138/ijdd.2010.0975.0215.03058     Document Type: Article

References (21)

1. O'Brien RD. Fats and Oils: Formulating and Processing for Applications. CRC Press: Boca Raton; 2004.
2. Keng PS, Basri M, Zakaria MRS, Abdul Rahman MB, Ariff AB, Abbdul Rahman RNZ, Salleh AB. Newly synthesized palm esters for cosmetics industry. Indus Crops prod 2009; 29 (1): 37-44.
3. Keng PS, Mahiran B, Abdul Rahman MB, Salleh AB, Abdul Rahman RNZ, Ariff A. Optimization of palm-based wax esters production using statistical experimental designs. J Oleo Sci 2005; 54: 519-528.
4. Keng PS, Mahiran B, Abdul Rahman MB, Salleh AB, Abdul Rahman RNZ, Ariff A. Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor. Bioresource Technol 2008; 99: 6097-6104.
5. Lakatos-Szabó J, Lakatos I. Effect of non-ionic surfactants on interfacial rheological properties of crude oil/water systems. Prog Colloid Poly Sci 1997; 105: 302-310.
6. Peltonen L, Hirvonen J, Yliruusi J. The behavior of sorbitan surfactants at the water-oil interface: Straight-chained hydrocarbons from pentane to dodecane as an oil phase. J Colloid Int Sci 2001: 240: 272-276.
7. Hayati IN, Binche M, Chinping T, Aini IN. Stability and rheology of concentrated O/W emulsions based on soybean oil/palm kernel olein blends. Food Res Int 2007; 40: 1051-1061.
8. Kónya M, Dékány I, Erõs I. X-ray investigation of the role of the mixed emulsifier in the structure formation in O/W creams. Coll Poly Sci 2007; 285: 657-663.
9. Baroli B, López-Quintela MA, Delgado-Charro MB, Fadda, AM, Blanco-Méndez J. Micro-emulsions for topical delivery of 8-methoxsalen. J Contr Rel 2000; 69: 209-218.
10. Whitehead K, Karr N, Mitragotri S. Safe and effective permeation enhancers for oral drug delivery. Inflammopharmacology 2007; 25: 1782-1788.
11. Fang J-Y, Yu S-Y, Pao-Chuwu H, Huang Y-B, Tsai Y-H. In vitro skin permeation of estradiol from various proniosome formulations. Int J Pharm 2001; 215: 91-99.
12. Marrzan LL, Samseth J, Quintela ML. Structure of concentrated nonionic surfactant micro-emulsions studied by small angle neutron scattering. J De Physique IV 1993; 3: 165-169.
13. Korhonen M, Niskanen H, Kiesvaara J, Yliruusi J. Determination of optimal combination of surfactants in creams using rheology measurements. Int J Pharm 2000; 197: 143-151.
14. Gi H-J, Chen S-N, Hwang J-S, Tien C, Kuo MT. Studies of formation and interface of oil-water micro-emulsion. Chineese J Phys 1992; 30: 665-678.
15. Lia P, Ghosha A, Wagnera RF, Krillb S, Joshia YM, Serajuddina ATM. Effect of combined use of nonionic surfactant on formation of oil-in-water micro-emulsions. Int J Pharm 2005; 288: 27-34.
16. Cho YH, Kim S, Bae EK, Mok CK, Park J. Formulation of co surfactant-free O/W micro-emulsion using nonionic surfactant mixture. Food Eng Phys Prop 2008; 73: E115-E121.
17. Lawrence MJ, Rees GD. Micro-emulsion-based media as novel drug delivery systems. Adv Dr Del Rev 2000; 45: 89-121.
18. Prinderre P, Piccerelle P, Cauture E, Kalantzis G, Reynier JP, Joachim J. Formulation and evaluation of O/W emulsions using experimental design. Int J Pharm 1998; 163: 73-79.
19. Junginger HE. Ointments and creams as colloidal drug delivery system. In: Kreuter J, editors. Colloidal Drug Delivery Systems. New York: Marcel Dekker; 1994. p. 1-45.
20. Jiao J, Burgess DJ. Rheology and stability of Water-in-Oil-in-Water multiple emulsions containing Span 83 and Tween 80. AAPS 2003; 5: 1-12.
21. Barakat Y, Gendy TS, Ibrahim V. Surfactants with natural hydrophobic tails HLB-CMC relationship of polyoxyethylenated cholesterol. Aust J Basic Appl Sci 2008; 2: 372-380.