Update lecture: Benign diseases of the exocrine pancreas

Digestive Diseases

Volumn 29, Issue SUPPL. 1, 2011, Pages 9-16

  Mössner, Joachim ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

Author keywords

Acute pancreatitis; Chronic pancreatitis; Exocrine pancreatic physiology; Genetics

Indexed keywords

BICARBONATE; CATHEPSIN; CHOLECYSTOKININ; FIBROBLAST GROWTH FACTOR; METALLOPROTEINASE; PROTEINASE; PROTEINASE INHIBITOR; SECRETIN; TRYPSIN; TRYPSINOGEN; TYROSINE; ZYMOGEN GRANULE;

ACINAR CELL; ACUTE HEMORRHAGIC PANCREATITIS; ACUTE PANCREATITIS; APOPTOSIS; BILIARY TRACT ENDOSCOPY; CALCIUM SIGNALING; CHRONIC PANCREATITIS; CONFERENCE PAPER; CYSTIC FIBROSIS; DISEASE COURSE; ENDOPLASMIC RETICULUM; ENDOSCOPIC SURGERY; ENZYME ACTIVATION; FIBROSIS; GENETIC LINKAGE; HUMAN; LYSOSOME; MULTIPLE ORGAN FAILURE; NONHUMAN; PANCREAS EXOCRINE INSUFFICIENCY; PANCREAS FUNCTION TEST; PANCREAS SECRETION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEPSIS; STELLATE CELL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

GERMANY; HEALTH PLANNING GUIDELINES; HUMANS; PANCREAS, EXOCRINE; PANCREATIC DISEASES; PANCREATITIS;

EID: 81855191265     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000331682     Document Type: Conference Paper

References (26)

1. Williams JA: Regulation of acinar cell function in the pancreas. Curr Opin Gastroenterol 2010; 26: 478-483.
2. Williams JA, Chen X, Sabbatini ME: Small G proteins as key regulators of pancreatic digestive enzyme secretion. Am J Physiol Endocrinol Metab 2009; 296:E405-E414.
3. Sabbatini ME, Bi Y, Ji B, Ernst SA, Williams JA: CCK activates RhoA and Rac1 differentially through G α 13 and G α q in mouse pancreatic acini. Am J Physiol Cell Physiol 2010; 298:C592-C601.
4. Guo L, Sans MD, Gurda GT, Lee SH, Ernst SA, Williams JA: Induction of early response genes in trypsin inhibitor-induced pancreatic growth. Am J Physiol Gastrointest Liver Physiol 2007; 292:G667-G677.
5. Keller J, Holst JJ, Layer P: Inhibition of human pancreatic and biliary output but not intestinal motility by physiological intraileal lipid loads. Am J Physiol Gastrointest Liver Physiol 2006; 290:G704-G709.
6. Choi M, Moschetta A, Bookout AL, Peng L, Umetani M, Holmstrom SR, Suino-Powell K, Xu HE, Richardson JA, Gerard RD, Mangelsdorf DJ, Kliewer SA: Identification of a hormonal basis for gallbladder filling. Nat Med 2006; 12: 1253-1255. (Pubitemid 44706926)
7. Petrov MS, Shanbhag S, Chakraborty M, Phillips AR, Windsor JA: Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis. Gastroenterology 2010; 139: 813-820.
8. Orlichenko L, Singh V: Trafficking of cathepsin B containing organelles to the autophagosome in an ARF-1-dependent manner is required for caerulein-induced trypsinogen activation. Gastroenterology 2011; 140(suppl 1):237.
9. Sah RP, Dawra R, Bekolay A, Dudeja V, Saluja A: Ashok Saluja trypsinogen activation is not required for the pathogenesis of chronic pancreatitis. Gastroenterology 2011; 140 (suppl 1):126.
10. Behrendorff N, Floetenmeyer M, Schwiening C, Thorn P: Protons released during pancreatic acinar cell secretion acidify the lumen and contribute to pancreatitis in mice. Gastroenterology 2010; 139: 1711-1720, e1-e5.
11. Gerasimenko JV, Lur G, Sherwood MW, Ebisui E, Tepikin AV, Mikoshiba K, Gerasimenko OV, Petersen OH: Pancreatic protease activation by alcohol metabolite depends on Ca 2+ release via acid store IP 3 receptors. Proc Natl Acad Sci USA 2009; 106: 10758-10763.
12. Whitcomb DC, Gorry MC, Preston RA, Furey W, Sossenheimer MJ, Ulrich CD, Martin SP, Gates LK Jr, Amann ST, Toskes PP, Liddle R, McGrath K, Uomo G, Post JC, Ehrlich GD: Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996; 14: 141-145. (Pubitemid 26338792)
13. Teich N, Mössner J: Hereditary chronic pancreatitis. Best Pract Res Clin Gastroenterol 2008; 2: 115-130.
14. Sharer N, Schwarz M, Malone G, Howarth A, Painter J, Super M, Braganza J: Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. N Engl J Med 1998; 339: 645-652. (Pubitemid 28402088)
15. Cohn JA, Friedman KJ, Noone PG, Knowles MR, Silverman LM, Jowell PS: Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med 1998; 339: 653-658. (Pubitemid 28402089)
16. Witt H, Luck W, Hennies HC, Classen M, Kage A, Lass U, Landt O, Becker M: Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000; 25: 213-216. (Pubitemid 30394996)
17. Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvári B, Landt O, Schulz HU, Gress TM, Pfützer R, Löhr M, Kovacs P, Blüher M, Stumvoll M, Choudhuri G, Hegyi P, te Morsche RH, Drenth JP, Truninger K, Macek M Jr, Puhl G, Witt U, Schmidt H, Büning C, Ockenga J, Kage A, Groneberg DA, Nickel R, Berg T, Wiedenmann B, Bödeker H, Keim V, Mössner J, Teich N, Sahin-Tóth M: Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nat Genet 2008; 40: 78-82.
18. Chiari H: Über Selbstverdauung des menschlichen Pankreas. Z Heilkunde 1896; 17: 69-96.
19. Apte M, Pirola RC, Wilson JS: The fibrosis of chronic pancreatitis: New insights into the role of pancreatic stellate cells. Antioxid Redox Signal 2011, E-pub ahead of print.
20. Ayub K, Imada R, Slavin J: Endoscopic retrograde cholangiopancreatography in gallstone-associated acute pancreatitis. Cochrane Database Syst Rev 2004; 4:CD003630.
21. Seifert H, Wehrmann T, Schmitt T, Zeuzem S, Caspary WF: Retroperitoneal endoscopic debridement for infected peripancreatic necrosis. Lancet 2000; 356: 653-655. (Pubitemid 30627596)
22. Raczynski S, Teich N, Borte G, Wittenburg H, Mössner J, Caca K: Percutaneous transgastric irrigation drainage in combination with endoscopic necrosectomy in necrotizing pancreatitis (with videos). Gastrointest Endosc 2006; 64: 420-424. (Pubitemid 44233575)
23. Van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH, van Goor H, Schaapherder AF, van Eijck CH, Bollen TL, van Ramshorst B, Nieuwenhuijs VB, Timmer R, Laméris JS, Kruyt PM, Manusama ER, van der Harst E, van der Schelling GP, Karsten T, Hesselink EJ, van Laarhoven CJ, Rosman C, Bosscha K, de Wit RJ, Houdijk AP, van Leeuwen MS, Buskens E, Gooszen HG; Dutch Pancreatitis Study Group: A step-up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med 2010; 362: 1491-1502.
24. Mössner J, Keim V, Niederau C, Büchler M, Singer MV, Lankisch PG, Göke B: Guidelines for therapy of chronic pancreatitis. Consensus Conference of the German Society of Digestive and Metabolic Diseases, Halle, November 21-23, 1996 (in German). Z Gastroenterol 1998; 36: 359-367.
25. Siegmund E, Löhr JM, Schuff-Werner P: The diagnostic validity of non-invasive pancreatic function tests -a meta-analysis (in German). Z Gastroenterol 2004; 42: 1117-1128. (Pubitemid 39486910)
26. Chari ST: Diagnosis of autoimmune pancreatitis using its five cardinal features: Introducing the Mayo Clinic's HISORT criteria. J Gastroenterol 2007; 42(suppl 18):39-41. (Pubitemid 46863936)