Three-year outcomes of a Canadian multicenter study of accelerated partial breast irradiation using conformal radiation therapy

International Journal of Radiation Oncology Biology Physics

Volumn 81, Issue 5, 2011, Pages 1220-1227

  Berrang, Tanya S ^a,b   Olivotto, Ivo ^a,b   Kim, Do Hoon ^c,d   Nichol, Alan ^a,b   Cho, B C John ^e,f   Mohamed, Islam G ^a,b   Parhar, Tarnjit ^a,b   Wright, J R ^c,d   Truong, Pauline ^a,b   Tyldesley, Scott ^a,b   Sussman, Jonathan ^c,d   Wai, Elaine ^a,b   Whelan, Tim ^c,d  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c JURAVINSKI CANCER CENTRE   (Canada)

^d MCMASTER UNIVERSITY   (Canada)

^e PRINCESS MARGARET HOSPITAL   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

Accelerated partial breast irradiation; Breast cancer; Cosmesis; Outcomes; Toxicity

Indexed keywords

ACCELERATED PARTIAL BREAST IRRADIATION; BREAST CANCER; BREAST CONSERVING SURGERY; COMPUTED TOMOGRAPHY SCAN; CONFORMAL RADIATION THERAPY; COSMESIS; DISEASE FREE SURVIVAL; DUCTAL CARCINOMA IN SITU; EARLY-STAGE BREAST CANCER; EXTERNAL BEAM; HYPERPIGMENTATION; HYPOPIGMENTATION; LOCAL CONTROL; LOCAL RECURRENCE; MULTICENTER STUDY; NODE-NEGATIVE; OUTCOMES; PHOTON BEAMS; PROSPECTIVE STUDY; TIME POINTS;

COMPUTERIZED TOMOGRAPHY; DISEASE CONTROL; DISEASES; IRRADIATION; RADIOTHERAPY; TOMOGRAPHY;

TOXICITY;

ACCELERATED PARTIAL BREAST IRRADIATION; ADULT; AGED; ARTICLE; BREAST CANCER; BREAST SURGERY; BREAST TUMOR; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DISEASE FREE SURVIVAL; DOSIMETRY; EARLY CANCER; EDEMA; EXTERNAL BEAM RADIOTHERAPY; FATIGUE; FEMALE; FOLLOW UP; HUMAN; HYPERPIGMENTATION; HYPOPIGMENTATION; INTRADUCTAL CARCINOMA; IPSILATERAL BREAST TUMOR RECURRENCE; MAJOR CLINICAL STUDY; MASTALGIA; MORBIDITY; MULTICENTER STUDY; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DERMATITIS; RADIATION DOSE FRACTIONATION; SEROMA; SKIN INDURATION; SKINFOLD; TELANGIECTASIA; TREATMENT DURATION; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CANADA; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; DISEASE-FREE SURVIVAL; DOSE FRACTIONATION; FEASIBILITY STUDIES; FEMALE; HUMANS; MASTECTOMY, SEGMENTAL; MIDDLE AGED; PHOTONS; PROSPECTIVE STUDIES; RADIATION INJURIES; RADIOTHERAPY, CONFORMAL; SEROMA; TIME FACTORS; TREATMENT OUTCOME; TUMOR BURDEN;

EID: 81855185366     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.07.2003     Document Type: Article

References (29)

1. C. Polgar, J. Fodor, and T. Major Breast-conserving treatment with partial or whole breast irradiation for low-risk invasive breast carcinoma: 5-year results of a randomized trial Int J Radiat Oncol Biol Phys 69 2007 694 702 (Pubitemid 47418409)
2. F.A. Vicini, P. Chen, and M. Wallace Interim cosmetic results and toxicity using 3D conformal External Beam radiotherapy to deliver accelerated partial breast irradiation in patients with early-stage breast cancer treated with breast-conserving therapy Int J Radiat Oncol Biol Phys 69 2007 1124 1130 (Pubitemid 47625835)
3. B.V. Offersen, M. Overgaard, N. Kroman, and J. Overgaard Accelerated partial breast irradiation as part of breast conserving therapy of early breast carcinoma: A systematic review Radiother Oncol 90 2009 1 12
4. M.E. Sanders, T. Scroggins, F.L. Ampil, and B.D. Li Accelerated partial breast irradiation in early-stage breast cancer J Clin Oncol 25 2007 996 1002 (Pubitemid 350002866)
5. B.D. Smith, D.W. Arthur, and T.A. Buchholz Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology Int J Radiat Oncol Biol Phys 74 2009 987 1001
6. L.R. Prosnitz, J. Horton, and P.E. Wallner Accelerated partial breast irradiation: Caution and concern from an ASTRO task force Int J Radiat Oncol Biol Phys 74 2009 981 984
7. C. Polgár, E.V. Limbergen, and R. Pötter Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: Recommendations of the Gropue Europeen de Curietherapie-European Society for Therapueutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009) Radiother Oncol 94 2010 264 273
8. S.C. Formenti, B. Rosenstein, K.A. Skinner, and G. Jozsef T1 stage breast cancer: Adjuvant hypofractionated conformal radiation therapy to tumor bed in selected postmenopausal breast cancer patients - pilot feasibility study Radiother Oncol 222 2002 171 178 (Pubitemid 34031484)
9. S.C. Formenti, M.T. Truong, and J.D. Goldberg Prone accelerated partial breast irradiation after breast-conserving surgery: Preliminary clinical results and dose-volume histogram analysis Int J Radiat Oncol Biol Phys 60 2004 493 504 (Pubitemid 39233469)
10. A.G. Taghian, M. Alm El-Din, and B.L. Smith Interim results of a phase I/II trial of 3D-conformal external beam accelerated partial breast irradiation in patients with early breast cancer Int J Radiat Oncol Biol Phys 72 1, Suppl. 1 2008 S4
11. R. Jagsi, M. Ben-David, and J. Moran Adverse cosmesis in a protocol investigating IMRT with active breathing control for accelerated partial breast irradiation (APBI) Int J Radiat Oncol Biol Phys 72 1, Suppl. 1 2008 S153
12. C. Leonard, D. Carter, and D. Howell A prospective trial of accelerated partial breast intensity modulated radiotherapy Int J Radiat Oncol Biol Phys 72 Suppl 1 2008 S152
13. R. Jagsi, D. Phil, and M.A. Ben-David Unacceptable cosmesis in a protocol investigating intensity-modulated radiotherapy with active breathing control for accelerated partial-breast irradiation Int J Radiat Oncol Biol Phys 76 2010 71 78
14. J.T. Hepel, M. Tokita, and S.G. MacAusland Toxicity of three-dimensional conformal radiotherapy for accelerated partial breast irradiation Int J Radiat Oncol Biol Phys 75 2009 1290 1296
15. F. Vicini, K. Winter, and J. Wong Initial efficacy results of RTOG 0319: Three-dimensional conformal radiation therapy (3D-CRT) confined to the region of the lumpectomy cavity for stage I/ II breast carcinoma Int J Radiat Oncol Biol Phys 77 2010 1120 1127
16. P.Y. Chen, M. Wallace, and C. Mitchell Four-year efficacy, cosmesis, and toxicity using three-dimensional conformal external beam radiation therapy to deliver accelerated partial breast irradiation Int J Radiat Oncol Biol Phys 76 2010 998 1004
17. P. Hopewood, J.S. Haviland, and G. Sumo Comparison of patient-reported breast, arm, and shoulder symptoms and body image after radiotherapy for early breast cancer: 5 year follow-up in the randomised Standardisation of Breast Radiotherapy (START) trials Lancet Oncol 11 2010 231 240
18. F. Vicini, K. Winter, and W. Straube A phase I/II trial to evaluate three-dimensional conformal radiation therapy confined to the region of the lumpectomy cavity for stage I/II breast carcinoma: Initial report of feasibility and reproducibility of Radiation Therapy Oncology Group (RTOG) study Int J Radiat Oncol Biol Phys 63 2005 1531 1537 (Pubitemid 41628053)
19. ClinicalTrials.gov. RAPID: Randomized trial of accelerated partial breast irradiation. Available at: http://www.clinicaltrials.gov/ct/show/NCT00282035. Last accessed June 1, 2010.
20. H.A. Kader, P.T. Truong, and R. Pai When is CT-based postoperative seroma most useful to plan partial breast radiotherapy? Evaluation of clinical factors affecting seroma volume and clarity Int J Radiat Biol Phys 72 2008 1064 1069
21. B.W. Cox, K.C. Horst, and S. Thornton Impact of increasing margin around the lumpectomy cavity to define the planning target volume for 3D conformal external beam accelerated breast irradiation Med Dosim 32 2007 254 262 (Pubitemid 350016879)
22. J.H. Borger, H. Kemperman, and H.S. Smitt Dose and volume effects on fibrosis after breast conserving therapy Int J Radiat Biol Phys 30 1994 1073 1081 (Pubitemid 24362516)
23. D.L. Hershman, X. Wang, and R. McBride Delay in initiating adjuvant radiotherapy following breast conservation surgery and its impact on survival Int J Radiat Oncol Biol Phys 65 2006 1353 1360 (Pubitemid 44425226)
24. I.A. Olivotto, M.L. Lesperance, and P.T. Truong Intervals longer than 20 weeks from breast-conserving surgery to radiation therapy are associated with inferior outcome for women with early-stage breast cancer who are not receiving chemotherapy J Clin Oncol 27 2009 16 23
25. O. Vujovic, E. Yu, and A. Cherian Eleven-year follow-up results in the delay of breast irradiation after conservative breast surgery in node-negative breast cancer patients Int J Radiat Oncol Biol Phys 64 2006 760 764 (Pubitemid 43183571)
26. T.J. Whelan, M. Levine, and J. Julian The effects of radiation therapy on quality of life of women with breast carcinoma Cancer 88 2000 2260 2266 (Pubitemid 30247125)
27. T. Whelan, R. MacKenzie, and J. Julian Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer J Natl Cancer Inst 94 2002 1143 1150 (Pubitemid 34919051)
28. T. Whelan, J. Pignol, and M. Levine Long-term results of hypofractionated radiation therapy for breast cancer N Engl J Med 362 2010 513 520
29. National Surgical Adjuvant, Breast and Bowel Project, (NSABP B-39/RTOG 0413). A randomized Phase III study of conventional whole breast irradiation (WBI) versus partial breast irradiation (PBI) for women with Stage 0, I, or II breast cancer. Available at: http://www.nsabp.pitt.edu/B-39.asp. Last accessed June 1, 2010.