메뉴 건너뛰기




Volumn 30, Issue 47, 2011, Pages 4721-4730

Expression of BARHL1 in medulloblastoma is associated with prolonged survival in mice and humans

Author keywords

Barhl1; Cerebellum; Medulloblastoma; Sonic hedgehog; Survival; Tumor

Indexed keywords

HOMEODOMAIN PROTEIN;

EID: 81855182063     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.173     Document Type: Article
Times cited : (17)

References (27)
  • 1
    • 17344377996 scopus 로고    scopus 로고
    • Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS
    • Bulfone A, Menguzzato E, Broccoli V, Marchitiello A, Gattuso C, Mariani M et al. (2000). Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS. Hum Mol Genet 9: 1443-1452.
    • (2000) Hum Mol Genet , vol.9 , pp. 1443-1452
    • Bulfone, A.1    Menguzzato, E.2    Broccoli, V.3    Marchitiello, A.4    Gattuso, C.5    Mariani, M.6
  • 2
    • 40349112978 scopus 로고    scopus 로고
    • Barhl1 regulatory sequences required for cell-specific gene expression and autoregulation in the inner ear and central nervous system
    • Chellappa R, Li SG, Pauley S, Jahan I, Jin KX, Xiang MQ. (2008). Barhl1 regulatory sequences required for cell-specific gene expression and autoregulation in the inner ear and central nervous system. Mol Cell Biol 28: 1905-1914.
    • (2008) Mol Cell Biol , vol.28 , pp. 1905-1914
    • Chellappa, R.1    Li, S.G.2    Pauley, S.3    Jahan, I.4    Jin, K.X.5    Xiang, M.Q.6
  • 3
    • 10344248682 scopus 로고    scopus 로고
    • Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development
    • Corrales J, Rocco G, Blaess S, Guo Q, Joyner A. (2004). Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development 131: 5581-5590.
    • (2004) Development , vol.131 , pp. 5581-5590
    • Corrales, J.1    Rocco, G.2    Blaess, S.3    Guo, Q.4    Joyner, A.5
  • 4
    • 36149000214 scopus 로고    scopus 로고
    • Medulloblastoma in childhood: New biological advances
    • Crawford JR, MacDonald TJ, Packer RJ. (2007). Medulloblastoma in childhood: new biological advances. Lancet Neurol 6: 1073-1085.
    • (2007) Lancet Neurol , vol.6 , pp. 1073-1085
    • Crawford, J.R.1    MacDonald, T.J.2    Packer, R.J.3
  • 5
    • 0035006794 scopus 로고    scopus 로고
    • Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules
    • Eberhart CG, Kaufman WE, Tihan T, Burger PC. (2001). Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules. J Neuropathol Exp Neurol 60: 462-469.
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 462-469
    • Eberhart, C.G.1    Kaufman, W.E.2    Tihan, T.3    Burger, P.C.4
  • 6
  • 7
    • 1642307767 scopus 로고    scopus 로고
    • Medulloblastoma: Signalling a change in treatment
    • Gilbertson RJ. (2004). Medulloblastoma: signalling a change in treatment. Lancet Oncol 5: 209-218.
    • (2004) Lancet Oncol , vol.5 , pp. 209-218
    • Gilbertson, R.J.1
  • 8
    • 20244370527 scopus 로고    scopus 로고
    • Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells
    • Hartmann W, Koch A, Brune H, Waha A, Schüller U, Dani I et al. (2005). Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. Am J Pathol 166: 1153-1162.
    • (2005) Am J Pathol , vol.166 , pp. 1153-1162
    • Hartmann, W.1    Koch, A.2    Brune, H.3    Waha, A.4    Schüller, U.5    Dani, I.6
  • 9
    • 61749085642 scopus 로고    scopus 로고
    • Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism
    • Heine VM, Rowitch DH. (2009). Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism. J Clin Invest 119: 267-277.
    • (2009) J Clin Invest , vol.119 , pp. 267-277
    • Heine, V.M.1    Rowitch, D.H.2
  • 10
    • 1942466507 scopus 로고    scopus 로고
    • Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia
    • Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. (2004). Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev 18: 937-951.
    • (2004) Genes Dev , vol.18 , pp. 937-951
    • Jeong, J.1    Mao, J.2    Tenzen, T.3    Kottmann, A.H.4    McMahon, A.P.5
  • 11
    • 52449119078 scopus 로고    scopus 로고
    • Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
    • Kool M, Koster J, Bunt J, Hasselt NE, Lakeman A, van Sluis P et al. (2008). Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLOS One Aug 3: e3088.
    • (2008) PLOS One Aug , vol.3
    • Kool, M.1    Koster, J.2    Bunt, J.3    Hasselt, N.E.4    Lakeman, A.5    Van Sluis, P.6
  • 12
    • 1642464987 scopus 로고    scopus 로고
    • Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene
    • Li S, Qiu F, Xu A, Price SM, Xiang M. (2004). Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene. J Neurosci 24: 3104-3114.
    • (2004) J Neurosci , vol.24 , pp. 3104-3114
    • Li, S.1    Qiu, F.2    Xu, A.3    Price, S.M.4    Xiang, M.5
  • 13
    • 0036638824 scopus 로고    scopus 로고
    • Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene
    • Li SG, Price SM, Cahill H, Ryugo DK, Shen MM, Xiang MQ. (2002). Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene. Development 129: 3523-3532.
    • (2002) Development , vol.129 , pp. 3523-3532
    • Li, S.G.1    Price, S.M.2    Cahill, H.3    Ryugo, D.K.4    Shen, M.M.5    Xiang, M.Q.6
  • 15
    • 33750543972 scopus 로고    scopus 로고
    • A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway
    • Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D et al. (2006). A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Res 66: 10171-10178.
    • (2006) Cancer Res , vol.66 , pp. 10171-10178
    • Mao, J.1    Ligon, K.L.2    Rakhlin, E.Y.3    Thayer, S.P.4    Bronson, R.T.5    Rowitch, D.6
  • 16
    • 0029585838 scopus 로고
    • A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum
    • Millen KJ, Hui CC, Joyner AL. (1995). A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum. Development 121: 3935-3945.
    • (1995) Development , vol.121 , pp. 3935-3945
    • Millen, K.J.1    Hui, C.C.2    Joyner, A.L.3
  • 17
    • 1642479166 scopus 로고    scopus 로고
    • Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells
    • Mo Z, Li S, Yang X, Xiang M. (2004). Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells. Development 131: 1607-1618.
    • (2004) Development , vol.131 , pp. 1607-1618
    • Mo, Z.1    Li, S.2    Yang, X.3    Xiang, M.4
  • 19
    • 0037165140 scopus 로고    scopus 로고
    • Prediction of central nervous system embryonal tumour outcome based on gene expression
    • Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME et al. (2002). Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415: 436-442.
    • (2002) Nature , vol.415 , pp. 436-442
    • Pomeroy, S.L.1    Tamayo, P.2    Gaasenbeek, M.3    Sturla, L.M.4    Angelo, M.5    McLaughlin, M.E.6
  • 20
    • 67650289584 scopus 로고    scopus 로고
    • Mechanisms of Hedgehog pathway activation in cancer and implications for therapy
    • Scales SJ, de Sauvage FJ. (2009). Mechanisms of Hedgehog pathway activation in cancer and implications for therapy. Trends Pharmacol Sci 30: 303-312.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 303-312
    • Scales, S.J.1    De Sauvage, F.J.2
  • 21
    • 48449105147 scopus 로고    scopus 로고
    • Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
    • Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG et al. (2008). Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell 14: 123-134.
    • (2008) Cancer Cell , vol.14 , pp. 123-134
    • Schüller, U.1    Heine, V.M.2    Mao, J.3    Kho, A.T.4    Dillon, A.K.5    Han, Y.G.6
  • 22
    • 36849013469 scopus 로고    scopus 로고
    • Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors
    • Schüller U, Zhao Q, Godinho SA, Heine VM, Medema RH, Pellman D et al. (2007). Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors. Mol Cell Biol 27: 8259-8270.
    • (2007) Mol Cell Biol , vol.27 , pp. 8259-8270
    • Schüller, U.1    Zhao, Q.2    Godinho, S.A.3    Heine, V.M.4    Medema, R.H.5    Pellman, D.6
  • 23
    • 0028568009 scopus 로고
    • Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma
    • Segal RA, Goumnerova LC, Kwon YK, Stiles CD, Pomeroy SL. (1994). Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci USA 91: 12867-12871.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12867-12871
    • Segal, R.A.1    Goumnerova, L.C.2    Kwon, Y.K.3    Stiles, C.D.4    Pomeroy, S.L.5
  • 24
    • 77950091343 scopus 로고    scopus 로고
    • Cerebellar stem cells act as medulloblastomainitiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas
    • Sutter R, Shakhova O, Bhagat H, Behesti H, Sutter C, Penkar S et al. (2010). Cerebellar stem cells act as medulloblastomainitiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas. Oncogene 29: 1845-1856.
    • (2010) Oncogene , vol.29 , pp. 1845-1856
    • Sutter, R.1    Shakhova, O.2    Bhagat, H.3    Behesti, H.4    Sutter, C.5    Penkar, S.6
  • 25
    • 0041670904 scopus 로고    scopus 로고
    • Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum
    • Weyer A, Schilling K. (2003). Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum. J Neurosci Res 73: 400-409.
    • (2003) J Neurosci Res , vol.73 , pp. 400-409
    • Weyer, A.1    Schilling, K.2
  • 26
    • 0030066459 scopus 로고    scopus 로고
    • Predominant expression of human Zic in cerebellar granule cell lineage and medulloblastoma
    • Yokota N, Aruga J, Takai S, Yamada K, Hamazaki M, Iwase T et al. (1996). Predominant expression of human Zic in cerebellar granule cell lineage and medulloblastoma. Cancer Res 56: 377-383.
    • (1996) Cancer Res , vol.56 , pp. 377-383
    • Yokota, N.1    Aruga, J.2    Takai, S.3    Yamada, K.4    Hamazaki, M.5    Iwase, T.6
  • 27
    • 2442720109 scopus 로고    scopus 로고
    • Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization
    • Yokota N, Mainprize TG, Taylor MD, Kohata T, Loreto M, Ueda S et al. (2004). Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization. Oncogene 23: 3444-3453.
    • (2004) Oncogene , vol.23 , pp. 3444-3453
    • Yokota, N.1    Mainprize, T.G.2    Taylor, M.D.3    Kohata, T.4    Loreto, M.5    Ueda, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.