Phosphodiesterase-5 inhibition prevents postcardiopulmonary bypass acute kidney injury in swine

Annals of Thoracic Surgery

Volumn 92, Issue 6, 2011, Pages 2168-2176

  Patel, Nishith N ^a   Lin, Hua ^a   Toth, Tibor ^b   Jones, Ceri ^a   Ray, Paramita ^c   Welsh, Gavin I ^a   Satchell, Simon C ^a   Sleeman, Philippa ^a   Angelini, Gianni D ^a   Murphy, Gavin J ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

^c WESTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATININE; INTERLEUKIN 18; NITRIC OXIDE; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CARDIOPULMONARY BYPASS; CELL STRESS; CREATININE CLEARANCE; CYTOKINE RELEASE; DISEASE ASSOCIATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM INJURY; EXPERIMENTAL PIG; HYPOXIA; INFLAMMATION; KIDNEY PROXIMAL TUBULE; NONHUMAN; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RENAL PROTECTION; URINALYSIS; VASCULAR ENDOTHELIUM;

ACUTE KIDNEY INJURY; ANIMALS; BIOLOGICAL MARKERS; CARDIOPULMONARY BYPASS; FEMALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHODIESTERASE 5 INHIBITORS; PIPERAZINES; PURINES; SULFONES; SWINE;

EID: 81855180850     PISSN: 00034975     EISSN: 15526259     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2011.07.002     Document Type: Article

References (27)

1. M. Haase, R. Bellomo, G. Matalanis, P. Calzavacca, D. Dragun, and A. Haase-Fielitz A comparison of the RIFLE and Acute Kidney Injury Network classifications for cardiac surgery-associated acute kidney injury: a prospective cohort study J Thorac Cardiovasc Surg 138 2009 1370 1376
2. K. Karkouti, D.N. Wijeysundera, and T.M. Yau Acute kidney injury after cardiac surgery: focus on modifiable risk factors Circulation 119 2009 495 502
3. Z. Ricci, D. Cruz, and C. Ronco The RIFLE criteria and mortality in acute kidney injury: a systematic review Kidney Int 73 2008 538 546 (Pubitemid 351264114)
4. J.F. Dasta, S.L. Kane-Gill, A.J. Durtschi, D.S. Pathak, and J.A. Kellum Costs and outcomes of acute kidney injury (AKI) following cardiac surgery Nephrol Dial Transplant 23 2008 1970 1974 (Pubitemid 351768157)
5. N.N. Patel, C.A. Rogers, G.D. Angelini, and G.J. Murphy Pharmacological therapies for the prevention of acute kidney injury following cardiac surgery: a systematic review Heart Fail Rev 2011 Mar 13 [E-pub ahead of print]
6. G.J. Murphy, H. Lin, and R.J. Coward An initial evaluation of post-cardiopulmonary bypass acute kidney injury in swine Eur J Cardiothorac Surg 36 2009 849 855
7. N.N. Patel, T. Toth, and C. Jones Prevention of post-cardiopulmonary bypass acute kidney injury by endothelin A receptor blockade Crit Care Med 39 2011 793 802
8. S. Muzaffar, N. Shukla, A. Srivastava, G.D. Angelini, and J.Y. Jeremy Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells Br J Pharmacol 146 2005 109 117 (Pubitemid 43086100)
9. J.A. Kellum Acute kidney injury Crit Care Med 36 Suppl 2008 141 145
10. R. Ascione, C.T. Lloyd, M.J. Underwood, W.J. Gomes, and G.D. Angelini On-pump versus off-pump coronary revascularization: evaluation of renal function Ann Thorac Surg 68 1999 493 498 (Pubitemid 29521099)
11. A.S. Shoker Application of the clearance concept to hyponatremic and hypernatremic disorders: a phenomenological analysis Clin Chem 40 1994 1220 1227 (Pubitemid 24205935)
12. C.R. Parikh, J. Mishra, and H. Thiessen-Philbrook Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery Kidney Int 70 2006 199 203 (Pubitemid 44000139)
13. R.W. Nims, J.C. Cook, and M.C. Krishna Colorimetric assays for nitric oxide and nitrogen oxide species formed from nitric oxide stock solutions and donor compounds Meth Enzymol 268 1996 93 105 (Pubitemid 26286352)
14. N. Shukla, R. Jones, R. Persad, G.D. Angelini, and J.Y. Jeremy Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits Eur J Pharmacol 517 2005 224 231 (Pubitemid 40977899)
15. K.H. Lim, A.P. Halestrap, G.D. Angelini, and M.S. Suleiman Propofol is cardioprotective in a clinically relevant model of normothermic blood cardioplegic arrest and cardiopulmonary bypass Exp Biol Med (Maywood) 230 2005 413 420 (Pubitemid 40827706)
16. S. Muzaffar, N. Shukla, G. Angelini, and J.Y. Jeremy Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells Circulation 110 2004 1140 1147 (Pubitemid 39319015)
17. R.J. Coward, G.I. Welsh, and J. Yang The human glomerular podocyte is a novel target for insulin action Diabetes 54 2005 3095 3102 (Pubitemid 43334361)
18. G.J. Murphy, T.W. Johnson, and M.H. Chamberlain Short- and long-term effects of cytochalasin D, paclitaxel and rapamycin on wall thickening in experimental porcine vein grafts Cardiovasc Res 73 2007 607 617 (Pubitemid 46091777)
19. A. Haase-Fielitz, R. Bellomo, and P. Devarajan Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgerya prospective cohort study Crit Care Med 37 2009 553 560
20. G. Lema, J. Urzua, and R. Jalil Decreased nitric oxide products in the urine of patients undergoing cardiac surgery J Cardiothorac Vasc Anesth 23 2009 188 194
21. P.F. Mount, and D.A. Power Nitric oxide in the kidney: functions and regulation of synthesis Acta Physiol (Oxford) 187 2006 433 446
22. O. Kwon, S.M. Hong, and G. Ramesh Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion Am J Physiol Renal Physiol 296 2009 F25 F33
23. M.S. Goligorsky, S.V. Brodsky, and E. Noiri Nitric oxide in acute renal failure: NOS versus NOS Kidney Int 61 2002 855 861 (Pubitemid 34175452)
24. M. Araujo, and W.J. Welch Oxidative stress and nitric oxide in kidney function Curr Opin Nephrol Hypertens 15 2006 72 77
25. L. Wu, and P.R. Mayeux Effects of the inducible nitric-oxide synthase inhibitor L-N(6)-(1-iminoethyl)-lysine on microcirculation and reactive nitrogen species generation in the kidney following lipopolysaccharide administration in mice J Pharmacol Exp Ther 320 2007 1061 1067 (Pubitemid 46294073)
26. E.M. Agency Revatio: sildenafil http://www.ema.europa.eu/ema Accessed October 9, 2010
27. S.D. Katz, K. Balidemaj, S. Homma, H. Wu, J. Wang, and S. Maybaum Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure J Am Coll Cardiol 36 2000 845 851