Future research in emergency medicine: Explanation or pragmatism? Large or small? Simple or complex?

Emergency Medicine Journal

Volumn 28, Issue 12, 2011, Pages 1004-1007

  Coats, Timothy J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBRINOLYTIC AGENT; CORTICOSTEROID;

ASTHMA; BLEEDING; CLINICAL PRACTICE; DEATH; EMERGENCY MEDICINE; EMERGENCY PHYSICIAN; EXPIRATORY FLOW RATE; FUNDING; HEAD INJURY; HEALTH CARE; HEALTH CARE POLICY; HEALTH CARE SYSTEM; HEALTH SERVICE; HUMAN; INJURY; MEDICAL EDUCATION; MEDICAL RESEARCH; MEDICAL SPECIALIST; MORTALITY; NOTE; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; RESEARCH; RISK; RISK REDUCTION; UNITED KINGDOM; UNITED STATES;

BIOMEDICAL RESEARCH; CLINICAL TRIALS AS TOPIC; EMERGENCY MEDICINE; FORECASTING; HUMANS;

EID: 81855170049     PISSN: 14720205     EISSN: 14720213     Source Type: Journal    
DOI: 10.1136/emermed-2011-200282     Document Type: Note

References (9)

1. Malakoff D. Spiralling costs threaten gridlock. Science 2008;322:210-13.
2. Dickinson K, Bunn F, Wentz R, et al. Size and quality of randomised controlled trials in head injury: review of published studies. BMJ 2000;320:1308-11. (Pubitemid 30245719)
3. Schwartz D, Lellouch J. Explanatory and pragmatic attitudes in therapeutic trials. J Chron Dis 1967;20:637-48.
4. Marshall E. Lemons, oranges and complexity. Science 2008;322:209.
5. Zwarenstein M, Treweek S. What kind of randomized trials do we need? J Clin Epidemiol 2009;62:461-3.
6. CRASH-2 Trial Collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH2). Lancet 2010;376:23-32.
7. Maclure M. Explaining pragmatic trials to pragmatic policymakers. J Clin Epidemiol 2009;62:476-8.
8. Tunis S, Stryer D, Clancy C. Practical clinical trials: increasing the value of clinical research for decision makers in clinical and health policy. JAMA 2003;290:1624-32. (Pubitemid 37430387)
9. Thorpe K, Zwatenstein M, Oxman A, et al. A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. J Clin Epidemiol 2009;62:464-75.