Simultaneous determination of tetrahydropalmatine and tetrahydroberberine in rat urine using dispersive liquid-liquid microextraction coupled with high-performance liquid chromatography

Journal of Separation Science

Volumn 34, Issue 22, 2011, Pages 3279-3286

  Zhang, Mingyong ^a,b   Le, Jian ^c   Wen, Jun ^a,b   Chai, Yifeng ^a,b   Fan, Guorong ^a,b   Hong, Zhanying ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI KEY LABORATORY FOR PHARMACEUTICAL METABOLITE RESEARCH   (China)

^c SHANGHAI INSTITUTE FOR FOOD AND DRUG CONTROL   (China)

Author keywords

Dispersive liquid liquid microextraction; HPLC UV; Tetrahydroberberine; Tetrahydropalmatine; Urine sample

Indexed keywords

DISPERSIVE LIQUID-LIQUID MICROEXTRACTION; HPLC-UV; TETRAHYDROBERBERINE; TETRAHYDROPALMATINE; URINE SAMPLE;

ALKALINITY; BODY FLUIDS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; METHANOL; ORGANIC SOLVENTS; RATS; SOLVENTS;

SOLVENT EXTRACTION;

CANADINE; CHLOROFORM; METHANOL; SODIUM HYDROXIDE; SOLVENT; TETRAHYDROPALMATINE;

ANIMAL EXPERIMENT; ARTICLE; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF QUANTITATION; LIQUID PHASE MICROEXTRACTION; NONHUMAN; PH; PRIORITY JOURNAL; RAT; RHIZOME; URINALYSIS; URINE;

ANIMALS; BERBERINE; BERBERINE ALKALOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; LIQUID PHASE MICROEXTRACTION; RATS;

CORYDALIS; RATTUS;

EID: 81755187197     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100588     Document Type: Article

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