Real-time predictions of drug release and end point detection of a coating operation by in-line near infrared measurements

International Journal of Pharmaceutics

Volumn 421, Issue 2, 2011, Pages 237-243

  Gendre, Claire ^a,b,c   Boiret, Mathieu ^c   Genty, Muriel ^c   Chaminade, Pierre ^a   Pean, Jean Manuel ^c  

^a University Paris Saclay   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Coating operation; Dissolution testing; End point determination; Near infrared spectroscopy (NIRS); Process analytical technology (PAT); Sustained release tablets

Indexed keywords

ETHYL CELLULOSE; MACROGOL; POLYVINYL ALCOHOL;

ARTICLE; DRUG COATING; DRUG RELEASE; DRUG SOLUBILITY; NEAR INFRARED SPECTROSCOPY; PRIORITY JOURNAL; SUSTAINED RELEASE FORMULATION;

CELLULOSE; CITRATES; COMPUTER SYSTEMS; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; MODELS, THEORETICAL; POLYVINYLS; REPRODUCIBILITY OF RESULTS; SOLUBILITY; SPECTROSCOPY, NEAR-INFRARED; TABLETS, ENTERIC-COATED;

EID: 81755165889     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.09.036     Document Type: Article

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