Apical-basal polarity in Drosophila neuroblasts is independent of vesicular trafficking

Molecular Biology of the Cell

Volumn 22, Issue 22, 2011, Pages 4373-4379

  Halbsgut, Nils ^a   Linnemannston̈s, Karen ^a   Zimmermann, Laura Isabel ^a   Wodarz, Andreas ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APICAL BASAL POLARITY; ARTICLE; CELL MEMBRANE; CELL MIGRATION; CELL POLARITY; CELL TYPE; DROSOPHILA; ENDOCYTOSIS; EPITHELIUM CELL; EXOCYTOSIS; GENE MUTATION; MUTANT; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL MEMBRANE; CELL POLARITY; DROSOPHILA; DROSOPHILA PROTEINS; DYNAMINS; ENDOCYTOSIS; EXOCYTOSIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEURAL STEM CELLS; PROTEIN KINASE C; PROTEIN TRANSPORT;

EID: 81755162748     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-03-0219     Document Type: Article

References (57)

1. Bello B, Reichert H, Hirth F (2006). The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila. Development 133, 2639-2648. (Pubitemid 44177885)
2. Benton R, St Johnston D (2003). Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells. Cell 115, 691-704. (Pubitemid 38030298)
3. Berdnik D, Torok T, Gonzalez-Gaitan M, Knoblich JA (2002). The endocytic protein alpha-adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell 3, 221-231.
4. Beronja S, Laprise P, Papoulas O, Pellikka M, Sisson J, Tepass U (2005). Essential function of Drosophila Sec6 in apical exocytosis of epithelial photoreceptor cells. J Cell Biol 169, 635-646. (Pubitemid 41002856)
5. Betschinger J, Mechtler K, Knoblich JA (2006). Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124, 1241-1253.
6. Blankenship JT, Fuller MT, Zallen JA (2007). The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identity. J Cell Sci 120, 3099-3110. (Pubitemid 47517092)
7. Bokel C, Schwabedissen A, Entchev E, Renaud O, Gonzalez-Gaitan M (2006). Sara endosomes and the maintenance of Dpp signaling levels across mitosis. Science 314, 1135-1139. (Pubitemid 44789042)
8. Chabu C, Doe CQ (2008). Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression. Development 135, 2739-2746.
9. Giansanti MG, Farkas RM, Bonaccorsi S, Lindsley DL, Wakimoto BT, Fuller MT, Gatti M (2004). Genetic dissection of meiotic cytokinesis in Drosophila males. Mol Biol Cell 15, 2509-2522. (Pubitemid 38580664)
10. Gonczy P (2008). Mechanisms of asymmetric cell division: flies and worms pave the way. Nat Rev Mol Cell Biol 9, 355-366.
11. Gonzalez-Gaitan M, Jackle H (1997). Role of Drosophila alpha-adaptin in presynaptic vesicle recycling. Cell 88, 767-776. (Pubitemid 27164265)
12. Harris KP, Tepass U (2008). Cdc42 and Par proteins stabilize dynamic adherens junctions in the Drosophila neuroectoderm through regulation of apical endocytosis. J Cell Biol 183, 1129-1143.
13. Harris TJ, Peifer M (2007). aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development. Dev Cell 12, 727-738. (Pubitemid 46667741)
14. He B, Guo W (2009). The exocyst complex in polarized exocytosis. Curr Opin Cell Biol 21, 537-542.
15. Hsu SC, Ting AE, Hazuka CD, Davanger S, Kenny JW, Kee Y, Scheller RH (1996). The mammalian brain rsec6/8 complex. Neuron 17, 1209-1219. (Pubitemid 27021105)
16. Hurov JB, Watkins JL, Piwnica-Worms H (2004). Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity. Curr Biol 14, 736-741. (Pubitemid 38503613)
17. Jaekel R, Klein T (2006). The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking. Dev Cell 11, 655-669. (Pubitemid 44644966)
18. Kee Y, Yoo JS, Hazuka CD, Peterson KE, Hsu SC, Scheller RH (1997). Subunit structure of the mammalian exocyst complex. Proc Natl Acad Sci USA 94, 14438-14443. (Pubitemid 28041392)
19. Kim S, Gailite I, Moussian B, Luschnig S, Goette M, Fricke K, Honemann-Capito M, Grubmuller H, Wodarz A (2009). Kinase-activity-independent functions of atypical protein kinase C in Drosophila. J Cell Sci 122, 3759-3771.
20. Knoblich JA (2008). Mechanisms of asymmetric stem cell division. Cell 132, 583-597.
21. Krahn MP, Egger-Adam D, Wodarz A (2009). PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts. Dev Cell 16, 901-908.
22. Krahn MP, Klopfenstein DR, Fischer N, Wodarz A (2010). Membrane targeting of Bazooka/PAR-3 is mediated by direct binding to phosphoinositide lipids. Curr Biol 20, 636-642.
23. Kusakabe M, Nishida E (2004). The polarity-inducing kinase Par-1 controls Xenopus gastrulation in cooperation with 14-3-3 and aPKC. EMBO J 23, 4190-4201. (Pubitemid 39546157)
24. Langevin J, Morgan MJ, Sibarita JB, Aresta S, Murthy M, Schwarz T, Camonis J, Bellaiche Y (2005). Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-cadherin trafficking from recycling endosomes to the plasma membrane. Dev Cell 9, 365-376. (Pubitemid 41235806)
25. Lee CY, Wilkinson BD, Siegrist SE, Wharton RP, Doe CQ (2006). Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev Cell 10, 441-449.
26. Lee T, Luo L (1999). Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22, 451-461. (Pubitemid 29159845)
27. Lloyd TE, Atkinson R, Wu MN, Zhou Y, Pennetta G, Bellen HJ (2002). Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell 108, 261-269. (Pubitemid 34161145)
28. Lu H, Bilder D (2005). Endocytic control of epithelial polarity and proliferation in Drosophila. Nat Cell Biol 7, 1232-1239.
29. Matern HT, Yeaman C, Nelson WJ, Scheller RH (2001). The Sec6/8 complex in mammalian cells: characterization of mammalian Sec3, subunit interactions, and expression of subunits in polarized cells. Proc Natl Acad Sci USA 98, 9648-9653. (Pubitemid 32769357)
30. Mehta SQ et al. (2005). Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron 46, 219-232. (Pubitemid 40545778)
31. Menut L, Vaccari T, Dionne H, Hill J, Wu G, Bilder D (2007). A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation. Genetics 177, 1667-1677. (Pubitemid 350277060)
32. Moberg KH, Schelble S, Burdick SK, Hariharan IK (2005). Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth. Dev Cell 9, 699-710. (Pubitemid 41555151)
33. Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008). Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45. Mol Biol Cell 19, 4167-4176.
34. Muller HA, Wieschaus E (1996). armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila. J Cell Biol 134, 149-163.
35. Murthy M, Garza D, Scheller RH, Schwarz TL (2003). Mutations in the exocyst component Sec5 disrupt neuronal membrane traffic, but neurotransmitter release persists. Neuron 37, 433-447. (Pubitemid 36183365)
36. Murthy M, Ranjan R, Denef N, Higashi ME, Schupbach T, Schwarz TL (2005). Sec6 mutations and the Drosophila exocyst complex. J Cell Sci 118, 1139-1150. (Pubitemid 40528685)
37. Murthy M, Schwarz TL (2004). The exocyst component Sec5 is required for membrane traffic and polarity in the Drosophila ovary. Development 131, 377-388. (Pubitemid 38181376)
38. Petronczki M, Knoblich JA (2001). DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila. Nat Cell Biol 3, 43-49. (Pubitemid 32114831)
39. Poodry CA (1990). shibire, a neurogenic mutant of Drosophila. Dev Biol 138, 464-472.
40. Qin H, Percival-Smith A, Li C, Jia CY, Gloor G, Li SS (2004). A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division. J Biol Chem 279, 11304-11312. (Pubitemid 38401627)
41. Rodriguez-Boulan E, Kreitzer G, Musch A (2005). Organization of vesicular trafficking in epithelia. Nat Rev Mol Cell Biol 6, 233-247. (Pubitemid 40314924)
42. Rolls MM, Albertson R, Shih HP, Lee CY, Doe CQ (2003). Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia. J Cell Biol 163, 1089-1098. (Pubitemid 37541884)
43. Schober M, Schaefer M, Knoblich JA (1999). Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts. Nature 402, 548-551.
44. Schuck S, Simons K (2004). Polarized sorting in epithelial cells: raft clustering and the biogenesis of the apical membrane. J Cell Sci 117, 5955-5964. (Pubitemid 40123962)
45. Shivas JM, Morrison HA, Bilder D, Skop AR (2010). Polarity and endocytosis: reciprocal regulation. Trends Cell Biol 20, 445-452.
46. Siegrist SE, Doe CQ (2005). Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts. Cell 123, 1323-1335. (Pubitemid 41821788)
47. Siegrist SE, Doe CQ (2006). Extrinsic cues orient the cell division axis in Drosophila embryonic neuroblasts. Development 133, 529-536. (Pubitemid 43273838)
48. Suzuki A, Ohno S (2006). The PAR-aPKC system: lessons in polarity. J Cell Sci 119, 979-987.
49. Tepass U, Theres C, Knust E (1990). crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell 61, 787-799.
50. TerBush DR, Maurice T, Roth D, Novick P (1996). The exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15, 6483-6494. (Pubitemid 26413781)
51. Thompson BJ, Mathieu J, Sung HH, Loeser E, Rorth P, Cohen SM (2005). Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev Cell 9, 711-720. (Pubitemid 41555152)
52. Vaccari T, Bilder D (2005). The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking. Dev Cell 9, 687-698. (Pubitemid 41555150)
53. Wodarz A (2005). Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts. Curr Opin Cell Biol 17, 475-481.
54. Wodarz A, Ramrath A, Grimm A, Knust E (2000). Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts. J Cell Biol 150, 1361-1374.
55. Wodarz A, Ramrath A, Kuchinke U, Knust E (1999). Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts. Nature 402, 544-547.
56. Wucherpfennig T, Wilsch-Brauninger M, Gonzalez-Gaitan M (2003). Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J Cell Biol 161, 609-624. (Pubitemid 36578584)
57. Zhang J, Schulze KL, Hiesinger PR, Suyama K, Wang S, Fish M, Acar M, Hoskins RA, Bellen HJ, Scott MP (2007). Thirty-one flavors of Drosophila rab proteins. Genetics 176, 1307-1322. (Pubitemid 46961123)