-
1
-
-
53449097279
-
Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7
-
Oshima T, Miwa H, Joh T. Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7. Am J Physiol Cell Physiol 2008; 295: C800-C806.
-
(2008)
Am J Physiol Cell Physiol
, vol.295
-
-
Oshima, T.1
Miwa, H.2
Joh, T.3
-
2
-
-
0027244454
-
Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans
-
Bjarnason I, Hayllar J, MacPherson AJ, Russell AS. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology 1993; 104: 1832-1847. (Pubitemid 23235480)
-
(1993)
Gastroenterology
, vol.104
, Issue.6
, pp. 1832-1847
-
-
Bjarnason, I.1
Hayllar, J.2
MacPherson, A.J.3
Russell, A.S.4
-
3
-
-
0034097624
-
Uncoupling of intestinal mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase are required for the development of NSAID-enteropathy in the rat
-
DOI 10.1046/j.1365-2036.2000.00723.x
-
Somasundaram S, Sigthorsson G, Simpson RJ, et al. Uncoupling of intestinal mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase are required for the development of NSAID-enteropathy in the rat. Aliment Pharmacol Ther 2000; 14: 639-650. (Pubitemid 30240758)
-
(2000)
Alimentary Pharmacology and Therapeutics
, vol.14
, Issue.5
, pp. 639-650
-
-
Somasundaram, S.1
Sigthorsson, G.2
Simpson, R.J.3
Watts, J.4
Jacob, M.5
Tavares, I.A.6
Rafi, S.7
Roseth, A.8
Foster, R.9
Price, A.B.10
Wrigglesworth, J.M.11
Bjarnason, I.12
-
4
-
-
33846927457
-
Small bowel enteropathy associated with chronic low-dose aspirin therapy
-
DOI 10.1016/S0140-6736(07)60282-7, PII S0140673607602827
-
Leung WK, Bjarnason I, Wong VW, Sung JJ, Chan FK. Small bowel enteropathy associated with chronic low-dose aspirin therapy. Lancet 2007; 369: 614. (Pubitemid 46241446)
-
(2007)
Lancet
, vol.369
, Issue.9561
, pp. 614
-
-
Leung, W.K.1
Bjarnason, I.2
Wong, V.W.3
Sung, J.J.4
Chan, F.K.5
-
5
-
-
77149140437
-
Randomized, double-blind, pilot study of geranylgeranylacetone versus placebo in patients taking low-dose entericcoated aspirin. Low-dose aspirin-induced small bowel damage
-
Shiotani A, Haruma K, Nishi R, et al. Randomized, double-blind, pilot study of geranylgeranylacetone versus placebo in patients taking low-dose entericcoated aspirin. Low-dose aspirin-induced small bowel damage. Scand J Gastroenterol 2010; 45: 292-298.
-
(2010)
Scand J Gastroenterol
, vol.45
, pp. 292-298
-
-
Shiotani, A.1
Haruma, K.2
Nishi, R.3
-
6
-
-
8744313771
-
Restoration of heat shock protein70 suppresses gastric mucosal inducible nitric oxide synthase expression induced by Helicobacter pylori
-
DOI 10.1002/pmic.200400951
-
Yeo M, Park HK, Kim DK, et al. Restoration of heat shock protein70 suppresses gastric mucosal inducible nitric oxide synthase expression induced by Helicobacter pylori. Proteomics 2004; 4: 3335-3342. (Pubitemid 39525281)
-
(2004)
Proteomics
, vol.4
, Issue.11
, pp. 3335-3342
-
-
Yeo, M.1
Park, H.-K.2
Kim, D.-K.3
Sung, W.C.4
Young, S.K.5
Sang, Y.C.6
Paik, Y.-K.7
Hahm, K.-B.8
-
7
-
-
65449128872
-
Heat-shock protein 70-overexpressing gastric epithelial cells are resistant to indomethacin-induced apoptosis
-
Hirata I, Naito Y, Handa O, et al. Heat-shock protein 70-overexpressing gastric epithelial cells are resistant to indomethacin-induced apoptosis. Digestion 2009; 79: 243-250.
-
(2009)
Digestion
, vol.79
, pp. 243-250
-
-
Hirata, I.1
Naito, Y.2
Handa, O.3
-
8
-
-
33750503155
-
Zinc l-carnosine protects colonic mucosal injury through induction of heat shock protein 72 and suppression of NF-kappaB activation
-
DOI 10.1016/j.lfs.2006.07.032, PII S0024320506005753
-
Odashima M, Otaka M, Jin M, et al. Zinc L-carnosine protects colonic mucosal injury through induction of heat shock protein 72 and suppression of NF-kappaB activation. Life Sci 2006; 79: 2245-2250. (Pubitemid 44666062)
-
(2006)
Life Sciences
, vol.79
, Issue.24
, pp. 2245-2250
-
-
Odashima, M.1
Otaka, M.2
Jin, M.3
Wada, I.4
Horikawa, Y.5
Matsuhashi, T.6
Ohba, R.7
Hatakeyama, N.8
Oyake, J.9
Watanabe, S.10
-
9
-
-
77954662908
-
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells
-
Massey AJ, Williamson DS, Browne H, et al. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells. Cancer Chemother Pharmacol 2010; 66: 535-545.
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, pp. 535-545
-
-
Massey, A.J.1
Williamson, D.S.2
Browne, H.3
-
11
-
-
0037040541
-
Protein folding. Molecular chaperones in the cytosol: From nascent chain to folded protein
-
DOI 10.1126/science.1068408
-
Hartl FU, Hayer-Hartl M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 2002; 295: 1852-1858. (Pubitemid 34214115)
-
(2002)
Science
, vol.295
, Issue.5561
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
12
-
-
3242879188
-
'The stress of dying': The role of heat shock proteins in the regulation of apoptosis
-
DOI 10.1242/jcs.01284
-
Beere HM. "The stress of dying": the role of heat shock proteins in the regulation of apoptosis. J Cell Sci 2004; 117: 2641-2651. (Pubitemid 38997248)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2641-2651
-
-
Beere, H.M.1
-
13
-
-
0018870320
-
Reserpine-induced gastric ulcers: Protection by lysosomal stabilization due to zinc
-
DOI 10.1016/0014-2999(80)90073-4
-
Pfeiffer CJ, Cho CH, Cheema A, Saltman D. Reserpine-induced gastric ulcers: protection by lysosomal stabilization due to zinc. Eur J Pharmacol 1980; 61: 347-353. (Pubitemid 10156073)
-
(1980)
European Journal of Pharmacology
, vol.61
, Issue.4
, pp. 347-353
-
-
Pfeiffer, C.J.1
Cho, C.H.2
Cheema, A.3
Saltman, D.4
-
14
-
-
0022477265
-
Protection by metals against ethanol-induced gastric mucosal injury in the rat. Comparative biochemical and pharmacologic studies implicate protein sulfhydryls
-
Dupuy D, Szabo S. Protection by metals against ethanol-induced gastric mucosal injury in the rat. Comparative biochemical and pharmacologic studies implicate protein sulfhydryls. Gastroenterology 1986; 91: 966-974. (Pubitemid 16014605)
-
(1986)
Gastroenterology
, vol.91
, Issue.4
, pp. 966-974
-
-
Dupuy, D.1
Szabo, S.2
-
15
-
-
0033776181
-
Protection by polaprezinc, an anti-ulcer drug, against indomethacin-induced apoptosis in rat gastric mucosal cells
-
Fuji Y, Matsura T, Kai M, Kawasaki H, Yamada K. Protection by polaprezinc, an anti-ulcer drug, against indomethacin-induced apoptosis in rat gastric mucosal cells. Jpn J Pharmacol 2000; 84: 63-70.
-
(2000)
Jpn J Pharmacol
, vol.84
, pp. 63-70
-
-
Fuji, Y.1
Matsura, T.2
Kai, M.3
Kawasaki, H.4
Yamada, K.5
-
16
-
-
0025364641
-
2.
-
DOI 10.1007/BF01540402
-
Arakawa T, Satoh H, Nakamura A, et al. Effects of zinc L-carnosine on gastric mucosal and cell damage caused by ethanol in rats. Correlation with endogenous prostaglandin E2. Dig Dis Sci 1990; 35: 559-566. (Pubitemid 20172959)
-
(1990)
Digestive Diseases and Sciences
, vol.35
, Issue.5
, pp. 559-566
-
-
Arakawa, T.1
Satoh, H.2
Nakamura, A.3
Nebiki, H.4
Fukuda, T.5
Sakuma, H.6
Nakamura, H.7
Ishikawa, M.8
Seiki, M.9
Kobayashi, K.10
-
17
-
-
77955660458
-
Reactive oxygen species-quenching and anti-apoptotic effect of polaprezinc on indomethacin-induced small intestinal epithelial cell injury
-
Omatsu T, Naito Y, Handa O, et al. Reactive oxygen species-quenching and anti-apoptotic effect of polaprezinc on indomethacin-induced small intestinal epithelial cell injury. J Gastroenterol 2010; 45: 692-702.
-
(2010)
J Gastroenterol
, vol.45
, pp. 692-702
-
-
Omatsu, T.1
Naito, Y.2
Handa, O.3
-
19
-
-
0026076395
-
The membrane-stabilizing action of zinc carnosine (Z-103) in stress-induced gastric ulceration in rats
-
Cho CH, Luk CT, Ogle CW. The membrane-stabilizing action of zinc carnosine (Z-103) in stress-induced gastric ulceration in rats. Life Sci 1991; 49: PL189-PL194.
-
(1991)
Life Sci
, vol.49
-
-
Cho, C.H.1
Luk, C.T.2
Ogle, C.W.3
-
20
-
-
0036911785
-
Induction of a 72-kDa heat-shock protein in cultured rat gastric mucosal cells and rat gastric mucosa by zinc L-carnosine
-
DOI 10.1023/A:1021029927386
-
Odashima M, Otaka M, Jin M, et al. Induction of a 72-kDa heat-shock protein in cultured rat gastric mucosal cells and rat gastric mucosa by zinc Lcarnosine. Dig Dis Sci 2002; 47: 2799-2804. (Pubitemid 35471625)
-
(2002)
Digestive Diseases and Sciences
, vol.47
, Issue.12
, pp. 2799-2804
-
-
Odashima, M.1
Otaka, M.2
Jin, M.3
Konishi, N.4
Sato, T.5
Kato, S.6
Matsuhashi, T.7
Nakamura, C.8
Watanabe, S.9
-
21
-
-
0025236441
-
Effect on N-(3-Aminopropionyl)-L-histidinato zinc (Z-103) on healing and hydrocortisone-induced relapse of acetic acid ulcers in rats with limited food-intake-time
-
Ito M, Tanaka T, Suzuki Y. Effect of N-(3-aminopropionyl)-L-histidinato zinc (Z-103) on healing and hydrocortisone-induced relapse of acetic acid ulcers in rats with limited food-intake-time. Jpn J Pharmacol 1990; 52: 513-521. (Pubitemid 20127309)
-
(1990)
Japanese Journal of Pharmacology
, vol.52
, Issue.4
, pp. 513-521
-
-
Ito, M.1
Tanaka, T.2
Suzuki, Y.3
-
22
-
-
0030747182
-
Effect of Z-103 on TNB-induced colitis in rats
-
Yoshikawa T, Yamaguchi T, Yoshida N, et al. Effect of Z-103 on TNB-induced colitis in rats. Digestion 1997; 58: 464-468. (Pubitemid 27445615)
-
(1997)
Digestion
, vol.58
, Issue.5
, pp. 464-468
-
-
Yoshikawa, T.1
Yamaguchi, T.2
Yoshida, N.3
Yamamoto, H.4
Kitazumi, S.5
Takahashi, S.6
Naito, Y.7
Kondo, M.8
-
23
-
-
0036869939
-
Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori
-
Handa O, Yoshida N, Tanaka Y, et al. Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori. Can J Gastroenterol 2002; 16: 785-789. (Pubitemid 36054522)
-
(2002)
Canadian Journal of Gastroenterology
, vol.16
, Issue.11
, pp. 785-789
-
-
Handa, O.1
Yoshida, N.2
Tanaka, Y.3
Ueda, M.4
Ishikawa, T.5
Takagi, T.6
Matsumoto, N.7
Naito, Y.8
Yoshikawa, T.9
-
24
-
-
58849154606
-
Involvement of reactive oxygen species in indomethacin-induced apoptosis of small intestinal epithelial cells
-
Omatsu T, Naito Y, Handa O, et al. Involvement of reactive oxygen species in indomethacin-induced apoptosis of small intestinal epithelial cells. J Gastroenterol 2009; 44 Suppl. 19: 30-34.
-
(2009)
J Gastroenterol
, vol.44
, Issue.SUPPL. 19
, pp. 30-34
-
-
Omatsu, T.1
Naito, Y.2
Handa, O.3
-
25
-
-
33748749354
-
Methylparaben potentiates UV-induced damage of skin keratinocytes
-
DOI 10.1016/j.tox.2006.07.018, PII S0300483X06004641
-
Handa O, Kokura S, Adachi S, et al. Methylparaben potentiates UV-induced damage of skin keratinocytes. Toxicology 2006; 227: 62-72. (Pubitemid 44402851)
-
(2006)
Toxicology
, vol.227
, Issue.1-2
, pp. 62-72
-
-
Handa, O.1
Kokura, S.2
Adachi, S.3
Takagi, T.4
Naito, Y.5
Tanigawa, T.6
Yoshida, N.7
Yoshikawa, T.8
-
26
-
-
33748425100
-
Expression of HSP72 in the gastric mucosa is regulated by gastric acid in rats-Correlation of HSP72 expression with mucosal protection
-
DOI 10.1016/j.bbrc.2006.08.088, PII S0006291X06018778
-
Wada I, Otaka M, Jin M, et al. Expression of HSP72 in the gastric mucosa is regulated by gastric acid in rats-correlation of HSP72 expression with mucosal protection. Biochem Biophys Res Commun 2006; 349: 611-618. (Pubitemid 44344562)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.349
, Issue.2
, pp. 611-618
-
-
Wada, I.1
Otaka, M.2
Jin, M.3
Odashima, M.4
Komatsu, K.5
Konishi, N.6
Matsuhashi, T.7
Horikawa, Y.8
Ohba, R.9
Itoh, H.10
Watanabe, S.11
-
27
-
-
33750634125
-
Polaprezinc protects human colon cells from oxidative injury induced by hydrogen peroxide: Relevant to cytoprotective heat shock proteins
-
Ohkawara T, Nishihira J, Nagashima R, Takeda H, Asaka M. Polaprezinc protects human colon cells from oxidative injury induced by hydrogen peroxide: relevant to cytoprotective heat shock proteins. World J Gastroenterol 2006; 12: 6178-6181. (Pubitemid 44688168)
-
(2006)
World Journal of Gastroenterology
, vol.12
, Issue.38
, pp. 6178-6181
-
-
Ohkawara, T.1
Nishihira, J.2
Nagashima, R.3
Takeda, H.4
Asaka, M.5
-
28
-
-
77249168850
-
Zinc Supplementation with polaprezinc protects mouse hepatocytes against acetaminophen-induced toxicity via induction of heat shock protein 70
-
Nishida T, Ohata S, Kusumoto C, et al. Zinc Supplementation with polaprezinc protects mouse hepatocytes against acetaminophen-induced toxicity via induction of heat shock protein 70. J Clin Biochem Nutr 2010; 46: 43-51.
-
(2010)
J Clin Biochem Nutr
, vol.46
, pp. 43-51
-
-
Nishida, T.1
Ohata, S.2
Kusumoto, C.3
-
29
-
-
0037065502
-
Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
-
Antithrombotic Trialists' Collaboration
-
Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324: 71-86.
-
(2002)
BMJ
, vol.324
, pp. 71-86
-
-
-
30
-
-
0034797314
-
NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture
-
Tomisato W, Tsutsumi S, Rokutan K, Tsuchiya T, Mizushima T. NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture. Am J Physiol Gastrointest Liver Physiol 2001; 281: G1092-G1100.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Tomisato, W.1
Tsutsumi, S.2
Rokutan, K.3
Tsuchiya, T.4
Mizushima, T.5
-
31
-
-
0025359310
-
Studies on anti-ulcer effects of a new compound, zinc L-carnosine (Z-103)
-
Seiki M, Ueki S, Tanaka Y, et al. [Studies on anti-ulcer effects of a new compound, zinc L-carnosine (Z-103)]. Nippon Yakurigaku Zasshi 1990; 95: 257-269.
-
(1990)
Nippon Yakurigaku Zasshi
, vol.95
, pp. 257-269
-
-
Seiki, M.1
Ueki, S.2
Tanaka, Y.3
-
32
-
-
67749095999
-
Polaprezinc (Zinc L-carnosine) is a potent inducer of anti-oxidative stress enzyme, heme oxygenase (HO)-1 - A new mechanism of gastric mucosal protection
-
Ueda K, Ueyama T, Oka M, Ito T, Tsuruo Y, Ichinose M. Polaprezinc (Zinc L-carnosine) is a potent inducer of anti-oxidative stress enzyme, heme oxygenase (HO)-1 - a new mechanism of gastric mucosal protection. J Pharmacol Sci 2009; 110: 285-294.
-
(2009)
J Pharmacol Sci
, vol.110
, pp. 285-294
-
-
Ueda, K.1
Ueyama, T.2
Oka, M.3
Ito, T.4
Tsuruo, Y.5
Ichinose, M.6
-
33
-
-
0019258079
-
Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides
-
DOI 10.1002/jcp.1041020315
-
Hightower LE. Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides. J Cell Physiol 1980; 102: 407-427. (Pubitemid 11111648)
-
(1980)
Journal of Cellular Physiology
, vol.102
, Issue.3
, pp. 407-427
-
-
Hightower, L.E.1
-
34
-
-
0025769926
-
The stress (heat shock) proteins
-
Itoh H, Tashima Y. The stress (heat shock) proteins. Int J Biochem 1991; 23: 1185-1191.
-
(1991)
Int J Biochem
, vol.23
, pp. 1185-1191
-
-
Itoh, H.1
Tashima, Y.2
-
35
-
-
0016373748
-
Protein synthesis in salivary glands of Drosophila melanogaster: Relation to chromosome puffs
-
Tissières A, Mitchell HK, Tracy UM. Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. J Mol Biol 1974; 85: 389-398.
-
(1974)
J Mol Biol
, vol.85
, pp. 389-398
-
-
Tissières, A.1
Mitchell, H.K.2
Tracy, U.M.3
-
36
-
-
0034795370
-
Involvement of heat shock proteins in the healing of acetic acid-induced gastric ulcers in rats
-
Tsukimi Y, Nakai H, Itoh S, Amagase K, Okabe S. Involvement of heat shock proteins in the healing of acetic acid-induced gastric ulcers in rats. J Physiol Pharmacol 2001; 52: 391-406. (Pubitemid 32946279)
-
(2001)
Journal of Physiology and Pharmacology
, vol.52
, Issue.3
, pp. 391-406
-
-
Tsukimi, Y.1
Nakai, H.2
Itoh, S.3
Amagase, K.4
Okabe, S.5
-
37
-
-
0033776181
-
Protection by polaprezinc, an anti-ulcer drug, against indomethacin-induced apoptosis in rat gastric mucosal cells
-
Fuji Y, Matsura T, Kai M, Kawasaki H, Yamada K. Protection by polaprezinc, an anti-ulcer drug, against indomethacin-induced apoptosis in rat gastric mucosal cells. Jpn J Pharmacol 2000; 84: 63-70.
-
(2000)
Jpn J Pharmacol
, vol.84
, pp. 63-70
-
-
Fuji, Y.1
Matsura, T.2
Kai, M.3
Kawasaki, H.4
Yamada, K.5
|