Aged plasma transfusion increases mortality in a rat model of uncontrolled hemorrhage

Journal of Trauma - Injury, Infection and Critical Care

Volumn 71, Issue 5, 2011, Pages 1115-1119

  Letourneau, Phillip A ^a,b,c   McManus, Madonna ^a   Sowards, Kendell ^b,c   Wang, Weiwei ^b,c   Wang, Yao Wei ^b,c   Matijevic, Nena ^b,c   Pati, Shibani ^a   Wade, Charles E ^a,b,c   Holcomb, John B ^a,b,c  

^a Center for Translational Injury Research   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Blood storage; Endothelial permeability; Resuscitation; Thawed plasma

Indexed keywords

FRESH FROZEN PLASMA; RINGER LACTATE SOLUTION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD TRANSFUSION; CONTROLLED STUDY; HEMOSTASIS; LIVER HEMORRHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESUSCITATION; SURVIVAL RATE; THROMBOELASTOGRAPHY; TREATMENT OUTCOME;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD COMPONENT TRANSFUSION; DISEASE MODELS, ANIMAL; HEMORRHAGE; HEMOSTASIS; LIVER; PLASMA; RATS; RATS, SPRAGUE-DAWLEY; RESUSCITATION; SURVIVAL RATE; THROMBELASTOGRAPHY;

EID: 81455144952     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3182329210     Document Type: Article

References (40)

1. Holcomb JB, Jenkins D, Rhee P, et al. Damage control resuscitation: directly addressing the early coagulopathy of trauma. J Trauma. 2007; 62:307-310.
2. Beekley AC. Damage control resuscitation: a sensible approach to the exsanguinating surgical patient. Crit Care Med. 2008;36(7 suppl):S267-S274.
3. McMullin NR, Holcomb JB, Sondeen JL. Hemostatic resuscitation. In: Vincent JL, ed. Yearbook of Intensive Care and Emergency Medicine, 2006. Berlin Heidelberg: Springer-Verlag; 2006:265-278.
4. Borgman MA, Spinella PC, Perkins JG, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma. 2007;63:805-813. (Pubitemid 350287298)
5. Spinella PC, Holcomb JB. Resuscitation and transfusion principles for traumatic hemorrhagic shock. Blood Rev. 2009;23:231-240.
6. Johansson PI, Stensballe J. Effect of Haemostatic Control Resuscitation on mortality in massively bleeding patients: a before and after study. Vox Sang. 2009;96:111-118.
7. Holcomb JB, Wade CE, Michalek JE, et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008;248:447-458.
8. Cotton BA, Gunter OL, Isbell J, et al. Damage control hematology: the impact of a trauma exsanguination protocol on survival and blood product utilization. J Trauma. 2008;64:1177-1182; discussion 1182-1183. (Pubitemid 351671208)
9. Duchesne JC, Islam TM, Stuke L, et al. Hemostatic resuscitation during surgery improves survival in patients with traumatic-induced coagulopathy. J Trauma. 2009;67:33-37; discussion 37-39.
10. Duchesne JC, McSwain NE Jr, Cotton BA, et al. Damage control resuscitation: the new face of damage control. J Trauma. 2010;69:976-990.
11. Gonzalez EA, Moore FA, Holcomb JB, et al. Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma. 2007;62:112-119. (Pubitemid 46102840)
12. Teixeira PG, Inaba K, Shulman I, et al. Impact of plasma transfusion in massively transfused trauma patients. J Trauma. 2009;66:693-697.
13. Kashuk JL, Moore EE, Johnson JL, et al. Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer? J Trauma. 2008;65:261-270; discussion 270-271.
14. Stahel PF, Smith WR, Moore EE. Current trends in resuscitation strategy for the multiply injured patient. Injury. 2009;40(suppl 4):S27-S35.
15. Kor DJ, Gajic O. Blood product transfusion in the critical care setting. Curr Opin Crit Care. 2010;16:309-316.
16. Watson GA, Sperry JL, Rosengart MR, et al. Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma. 2009;67:221-227; discussion 228-230.
17. Snyder CW, Weinberg JA, McGwin G Jr, et al. The relationship of blood product ratio to mortality: survival benefit or survival bias? J Trauma. 2009;66:358 -362; discussion 362-364.
18. Scalea TM, Bochicchio KM, Lumpkins K, et al. Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients. Ann Surg. 2008;248:578-584.
19. Roback J. Technical Manual. 16th ed. Bethesda, MD: AABB; 2008.
20. von Heymann C, Keller MK, Spies C, et al. Activity of clotting factors in fresh-frozen plasma during storage at 4 degrees C over 6 days. Transfusion. 2009;49:913-920.
21. Matijevic N, Kostousov V, Wang YW, et al. Multiple levels of degradation dimish hemostatic potential of thawed plasma. J Trauma. 2011; 70:71-79.
22. Yazer MH, Cortese-Hassett A, Triulzi DJ. Coagulation factor levels in plasma frozen within 24 hours of phlebotomy over 5 days of storage at 1 to 6 degrees C. Transfusion. 2008;48:2525-2530.
23. Holcomb JB, McClain JM, Pusateri AE, et al. Fibrin sealant foam sprayed directly on liver injuries decreases blood loss in resuscitated rats. J Trauma. 2000;49:246-250.
24. Sondeen JL, Coppes VG, Holcomb JB. Blood pressure at which rebleeding occurs after resuscitation in swine with aortic injury. J Trauma. 2003;54(5 suppl):S110-S117. (Pubitemid 36758860)
25. Sperry JL, Ochoa JB, Gunn SR, et al. An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma. 2008;65:986-993.
26. Pati S, Matijevic N, Doursout MF, et al. Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw. J Trauma. 2010;69(suppl 1):S55-S63.
27. Offner PJ, Moore EE, Biffl WL, Johnson JL, Silliman CC. Increased rate of infection associated with transfusion of old blood after severe injury. Arch Surg. 2002;137:711-716; discussion 716-717.
28. Escobar GA, Cheng AM, Moore EE, et al. Stored packed red blood cell transfusion up-regulates inflammatory gene expression in circulating leukocytes. Ann Surg. 2007;246:129-134. (Pubitemid 47012217)
29. Weinberg JA, Cheng AM, Moore EE, et al. Duration of red cell storage influences mortality after trauma. J Trauma. 2010;69:1427-1431; discussion 1431-1432.
30. Welsby IJ, Lockhart E, Phillips-Bute B, et al. Storage age of transfused platelets and outcomes after cardiac surgery. Transfusion. 2010;50: 2311-2317.
31. Purdy FR, Tweeddale MG, Merrick PM. Association of mortality with age of blood transfused in septic ICU patients. Can J Anaesth. 1997;44: 1256-1261. (Pubitemid 28080688)
32. Fernandes CJ Jr, Akamine N, De Marco FV, De Souza JA, Lagudis S, Knobel E. Red blood cell transfusion does not increase oxygen consumption in critically ill septic patients. Crit Care. 2001;5:362-367. (Pubitemid 34130339)
33. Walsh TS, McArdle F, McLellan SA, et al. Does the storage time of transfused red blood cells influence regional or global indexes of tissue oxygenation in anemic critically ill patients? Crit Care Med. 2004;32: 364-371. (Pubitemid 38234112)
34. Matsuoka T, Hildreth J, Wisner DH. Liver injury as a model of uncontrolled hemorrhagic shock: resuscitation with different hypertonic regimens. J Trauma. 1995;39:674-680.
35. Kheirabadi BS, Crissey JM, Deguzman R, et al. Effects of synthetic versus natural colloid resuscitation on inducing dilutional coagulopathy and increasing hemorrhage in rabbits. J Trauma. 2008;64:1218 -1228; discussion 1228-1229. (Pubitemid 351671216)
36. Solomonov E, Hirsh M, Yahiya A, Krausz MM. The effect of vigorous fluid resuscitation in uncontrolled hemorrhagic shock after massive splenic injury. Crit Care Med. 2000;28:749-754. (Pubitemid 30174273)
37. Ng KF, Lam CC, Chan LC. In vivo effect of haemodilution with saline on coagulation: a randomized controlled trial. Br J Anaesth. 2002;88:475-480. (Pubitemid 34285195)
38. Schols SE, Feijge MA, Lancé MD, et al. Effects of plasma dilution on tissue-factor-induced thrombin generation and thromboelastography: partly compensating role of platelets. Transfusion. 2008;48:2384-2394.
39. Alam HB, Bice LM, Butt MU, et al. Testing of blood products in a polytrauma model: results of a multi-institutional randomized preclinical trial. J Trauma. 2009;67:856-864.
40. Fenger-Eriksen C, Tønnesen E, Ingerslev J, Sørensen B. Mechanisms of hydroxyethyl starch-induced dilutional coagulopathy. J Thromb Haemost. 2009;7:1099-1105.