Androgen receptor antagonists and anti-prostate cancer activities of some synthesized steroidal candidates

Chemical and Pharmaceutical Bulletin

Volumn 59, Issue 11, 2011, Pages 1363-1368

  Bahashwan, Saleh Abd El Rahman ^a   Al Omar, Mohamed Abd El Rahman ^b   Ezzeldin, Essam ^b   Abdalla, Mohamed Mostafa ^b   Fayed, Ahmed Abd El Hameed ^a   Amr, Abdel Galil El Sayed ^c,d  

^a TAIBAH UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c Univet Pharmaceutical Co   (Egypt)

^d NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Androgen; Antagonist; Antiandrogen; Cancer; Steroid

Indexed keywords

2 OXO 3 CYANO 6 (4 CHLOROPHENYL)ANDROST 3,5 DIENE[17,16 C]PYRANE; 2 OXO 3 CYANO 6 (4 CHLOROPHENYL)ANDROST 4 ENE[17,16 C]PYRAN 3 ONE; 2 OXO 3 CYANO 6 (4 CHLOROPHENYL)ANDROST 5 ENE[17,16 C]PYRAN 3 ONE; 2 OXO 3 CYANO 6 (4 CHLOROPHENYL)ANDROST 5 ENE[17,16 C]PYRAN 3B OL; 3 OXO 3 CYANO 6 (4 CHLOROPHENYL)ANDROST 4,6 DIENE[17,16 C]PYRANE 3 ONE; ANDROGEN RECEPTOR ANTAGONIST; ANTIANDROGEN; ANTINEOPLASTIC AGENT; BICALUTAMIDE; FINASTERIDE; PREDNISOLONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VIVO STUDY; LD 50; STRUCTURE ACTIVITY RELATION;

ANDROGEN RECEPTOR ANTAGONISTS; ANILIDES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HETEROCYCLIC COMPOUNDS; HUMANS; MALE; NITRILES; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TOSYL COMPOUNDS;

EID: 81455138237     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.59.1363     Document Type: Article

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