Dose-dependent liver tissue repair in chloroform plus thioacetamide acute hepatotoxicity

Environmental Toxicology and Pharmacology

Volumn 18, Issue 2, 2004, Pages 143-148

  Anand, Sathanandam S ^a   Murthy, Subramanyam N ^a   Mumtaz, Moiz M ^b   Mehendale, Harihara M ^a  

^a Department of Toxicology   (United States)

^b AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

Author keywords

Binary mixture; Dose response; Liver injury; Risk assessment; Tissue repair

Indexed keywords

ALANINE AMINOTRANSFERASE; CHLOROFORM; DNA; THIOACETAMIDE; THYMIDINE DERIVATIVE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CONVALESCENCE; HISTOPATHOLOGY; LIVER; LIVER INJURY; LIVER TOXICITY; MALE; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; TISSUE REPAIR;

ANIMALIA;

EID: 8144230753     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2004.02.010     Document Type: Article

References (37)

1. S.S. Anand, M.G. Soni, V.S. Vaidya, S.N. Murthy, M.M. Mumtaz, and H.M. Mehendale Extent and timeliness of tissue repair determines the dose-related hepatotoxicity of chloroform Int. J. Toxicol. 22 2003 1
2. S.S. Anand, S.N. Murthy, V.S. Vishal, M.M. Mumtaz, and H.M. Mehendale Tissue repair plays pivotal role in final outcome of supra-additive liver injury after chloroform and allyl alcohol binary mixture Food Chem. Toxicol. 41 2003 1123
3. S.S. Anand, V.S. Vaidya, B. Murali, M.M. Mumtaz, and H.M. Mehendale Hepatotoxicity of chloroform, trichloroethylene, and allyl alcohol ternary mixture is less than additive Toxicologist 72 2003 671
4. S.S. Anand, S.S. Devi, M. Murali, M.M. Mumtaz, and H.M. Mehendale Higher urinary elimination of trichloroethylene in presence of chloroform results in lower liver injury Int. J. Toxicol. 21 6 2002 525
5. U.M. Apte, P.B. Limaye, S.K. Ramaiah, V.S. Vaidya, T.J. Bucci, A. Warbritton, and H.M. Mehendale Upregulated promitogenic signaling via cytokines and growth factors: potential mechanism behind robust liver tissue repair in calorie-restricted rats upon toxic challenge Toxicol. Sci. 69 2002 448
6. K.A. Burton A study of the conditions and mechanisms of the diphenylamine reaction for positive colorimetric estimation of DNA Biochem. J. 62 1956 315
7. S. Chanda, R.S. Mangipudy, A. Warbritton, T.J. Bucci, and H.M. Mehendale Stimulated hepatic tissue repair underlies heteroprotection by thioacetamide against acetaminophen-induced lethality Hepatology 21 1995 477
8. J. Chauveau, Y. Moule, and C.M. Roniller Isolation of pure and unaltered liver nuclei morphology and biochemical composition Exp. Cell Res. 11 1956 317
9. R.B. Conolly, and B.E. Butterworth Biologically based dose-response model for hepatic toxicity: a mechanistically based replacement for traditional estimates of noncancer risk Toxicol. Lett. 82 1995 901 906
10. A.A. Constan, C.S. Sprankle, J.M. Peters, G.L. Kedderis, J.I. Everitt, B.A. Wong, F.L. Gonzalez, and B.E. Butterworth Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice Toxicol. Appl. Pharmacol. 160 1999 120 126
11. K. Dalhoff, H. Lausen, K. Bangert, H.E. Poulsen, M.E. Anderson, N. Grunnet, and N. Tygstrup Autoprotection in acetaminophen intoxication in rats: the role of liver regeneration Pharmacol. Toxicol. 88 2001 135
12. A. Dalu, P.S. Rao, and H.M. Mehendale Colchicine antimitosis abolishes resiliency of postnatally developing rats to chlordecone-amplified carbon tetrachloride hepatotoxicity and lethality Environ. Health Perspect. 106 1998 597
13. S.V. Digavalli, and H.M. Mehendale 2-Butoxyethanol autoprotection is due to resiliency of newly formed erythrocytes to hemolysis Arch. Toxicol. 69 1995 526
14. A. Greenwell, J.F. Foley, and R.R. Maronpot An enhancement method for immunohistochemical staining of proliferating cell nuclear antigen in archival rodent tissues Cancer Lett. 54 1991 251
15. HazDat, 2001. Agency for Toxic Substance and Disease Registry (ATSDR), Atlanta, GA.
16. S.G. Kulkarni, A. Warbritton, T.J. Bucci, and H.M. Mehendale Antimitotic intervention with colchicine alters the outcome of o-DCB-induced hepatotoxicity in Fischer 344 rats Toxicology 120 1997 79
17. P.B. Limaye, U.M. Apte, K. Shankar, T.J. Bucci, A. Warbritton, and H.M. Mehendale Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants Toxicol. Appl. Pharmacol. 191 2003 211
18. R.S. Mangipudy, S. Chanda, and H.M. Mehendale Tissue repair response as a function of dose in thioacetamide hepatotoxicity Environ. Health Perspect. 103 1995 260
19. R.S. Mangipudy, P.S. Rao, and H.M. Mehendale Effect of an antimitotic agent colchicine on thioacetamide hepatotoxicity Environ. Health Perspect. 104 1996 744
20. 4 at non-toxic doses Toxicol. Lett. 49 1989 215
21. H.M. Mehendale Amplified interactive toxicity of chemicals at nontoxic levels: mechanistic considerations and implications to public health Environ. Health Perspect. 102 Suppl. 9 1994 139
22. 3 hepatotoxicity Exp. Mol. Pathol. 51 1989 31
23. K.R. Purushotham, V.G. Lockard, and H.M. Mehendale Amplification of chloroform hepatotoxicity and lethality by dietary chlordecone (kepone) in mice Toxicol. Pathol. 16 1988 27
24. S.K. Ramaiah, U.M. Apte, and H.M. Mehendale Diet restriction as a protective mechanism in noncancer toxicity outcomes: a review Int. J. Toxicol. 19 2000 413
25. 4 autoprotection Toxicol. Pathol. 19 1991 597
26. 4 treated rats Biochem. Pharmacol. 42 1991 2323
27. V.C. Rao, and H.M. Mehendale Effect of antimitotic agent colchicine on carbon tetrachloride toxicity Arch. Toxicol. 67 1993 392
28. P.S. Rao, A. Dalu, S.G. Kulkarni, and H.M. Mehendale Stimulated tissue repair prevents lethality in isopropanol-induced potentiation of carbon tetrachloride hepatotoxicity Toxicol. Appl. Pharmacol. 140 1996 235
29. 4 hepatotoxicity: a novel dose-response Toxicology 118 1997 181
30. R.J. Ruch, J.E. Klaunig, and M.A. Pereira Selective resistance to cytotoxic agents in hepatocytes isolated from partially hepatectomized and neoplastic mouse liver Cancer Lett. 26 1985 295
31. M.G. Soni, R.S. Mangipudy, M.M. Mumtaz, and H.M. Mehendale Tissue repair response as a function of dose during trichloroethylene hepatotoxicity Toxicol. Sci. 42 1998 158
32. M.G. Soni, and H.M. Mehendale Role of tissue repair in toxicologic interactions among hepatotoxic organics Environ. Health Perspect. 106 Suppl. 6 1998 1307
33. M.G. Soni, S.K. Ramaiah, M.M. Mumtaz, H. Clewell, and H.M. Mehendale Toxicant-inflicted injury and stimulated tissue repair are opposing toxicodynamic forces in predictive toxicology Regul. Pharmacol. Toxicol. 19 1999 165
34. 4 autoprotection Toxicol. Pathol. 19 1991 47
35. 4 autoprotection Toxicol. Pathol. 22 1994 291
36. T. Wang, K. Shankar, M.J.J. Ronis, and H.M. Mehendale Potentiation of thiacetamide liver injury in diabetic rats is due to induced CYP2E1 J. Pharmacol. Exp. Ther. 294 2000 473
37. F. Wroblewski, and J.S. LaDue Serum glutamic-pyruvic transaminase in cardiac and hepatic disease Proceedings of Society of Experimental Biology and Medicine 1956 569 574