Transforming growth factor-ß/Smad signaling function in the aortopathies;Fator transformador de crescimento-ß/Smad como via de sinalização em aortopatias

Brazilian Journal of Cardiovascular Surgery

Volumn 26, Issue 3, 2011, Pages 393-403

  Yuan, Shi Min ^a   Wang, Jun ^b   Hu, Xiao Nan ^b   Li, De Min ^b   Jing, Hua ^b  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Aorta; Aorta, Thoracic; Smad Proteins; Transforming Growth Factor beta1

Indexed keywords

BIOLOGICAL MARKER; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ACUTE DISEASE; ANALYSIS OF VARIANCE; ARTICLE; CASE CONTROL STUDY; CORONARY ARTERY DISEASE; DISSECTING ANEURYSM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THORACIC AORTA ANEURYSM; WESTERN BLOTTING;

ACUTE DISEASE; ANALYSIS OF VARIANCE; ANEURYSM, DISSECTING; AORTIC ANEURYSM, THORACIC; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 81355164283     PISSN: 01027638     EISSN: 16789741     Source Type: Journal    
DOI: 10.5935/1678-9741.20110014     Document Type: Article

References (37)

1. Leof EB. TGF beta receptors and cell proliferation. http://www.researchgrantdatabase.com/g/5R01GM054200-03/TGFBETA-RECEPTORS-AND-CELL-PROLIFERATION/. [accessed on January 21, 2010].
2. 1 expression and effect in aortic smooth muscle cells from spontaneously hypertensive rats. Hypertension. 1991;17(6 Pt 2):896-901.
3. Wang W, Huang XR, Canlas E, Oka K, Truong LD, Deng C, et al. Essential role of Smad3 in angiotensin II-induced vascular fibrosis. Circ Res. 2006;98(8):1032-9.
4. Massagué J. TGF-beta signal transduction. Annu Rev Biochem. 1998;67:753-91.
5. Chai Y, Ito Y, Han J. TGF-ß signaling and its functional significance in regulating the fate of cranial neural crest cells. Crit Rev Oral Biol Med. 2003;14(2):78-88.
6. Makkar P, Metpally RP, Sangadala S, Reddy BV. Modeling and analysis of MH1 domain of Smads and their interaction with promoter DNA sequence motif. J Mol Graph Model. 2009;27(7):803-12.
7. Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, Rozenblum E, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science. 1996;271(5247):350-3.
8. 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci U S A. 1991;88(15):6642-6.
9. Kamimura S, Tsukamoto H. Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease. Hepatology. 1995;22(4 Pt 1):1304-9.
10. Dahiya R, Lee C, Haughney PC, Chui R, Ho R, Deng G. Differential gene expression of transforming growth factors D and ß, epidermal growth factor, keratinocyte growth factor, and their receptors in fetal and adult human prostatic tissues and cancer cell lines. Urology. 1996;48(6):963-70.
11. Dunfield LD, Dwyer EJ, Nachtigal MW. TGF ß-induced Smad signaling remains intact in primary human ovarian cancer cells. Endocrinology. 2002;143(4):1174-81.
12. Elliott RL, Blobe GC. Role of transforming growth factor ß in human cancer. J Clin Oncol. 2005;23(9):2078-93.
13. Pouliot F, Labrie C. Expression profile of agonistic smads in human breast cancer cells: absence of regulation by estrogens. Int J Cancer. 1999;81(1):98-103.
14. Jones JA, Spinale FG, Ikonomidis JS. Transforming growth factor-ß signaling in thoracic aortic aneurysm development: a paradox in pathogenesis. J Vasc Res. 2009;46(2):119-37.
15. Lesauskaite V, Tanganelli P, Sassi C, Neri E, Diciolla F, Ivanoviene L, et al. Smooth muscle cells of the media in the dilatative pathology of ascending thoracic aorta: morphology, immunoreactivity for osteopontin, matrix metalloproteinases, and their inhibitors. Hum Pathol. 2001;32(9):1003-11.
16. Dietz HC. TGF-ß in the pathogenesis and prevention of disease: a matter of aneurysmic proportions. J Clin Invest. 2010;120(2):403-7. doi: 10.1172/JCI42014.
17. 1 mRNA expression after nontransmural myocardial infarction in rats: effects of angiotensin converting enzyme inhibition and angiotensin II type 1 receptor blockade. Basic Res Cardiol. 1999;94(4):246-53.
18. Thompson NL, Bazoberry F, Speir EH, Casscells W, Ferrans VJ, Flanders KC, et al. Transforming growth factor ß-1 in acute myocardial infarction in rats. Growth Factors. 1988;1(1):91-9.
19. Gomez D, Al Haj Zen A, Borges LF, Philippe M, Gutierrez PS, Jondeau G, et al. Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway. J Pathol. 2009;218(1):131-42.
20. Ward MR, Agrotis A, Kanellakis P, Dilley R, Jennings G, Bobik A. Inhibition of protein tyrosine kinases attenuates increases in expression of transforming growth factor-ß isoforms and their receptors following arterial injury. Arterioscler Thromb Vasc Biol. 1997;17(11):2461-70.
21. Dawes LJ, Sleeman MA, Anderson IK, Reddan JR, Wormstone IM. TGFß /Smad4-dependent and-independent regulation of human lens epithelial cells. Invest Ophthalmol Vis Sci. 2009;50(11):5318-27.
22. Saika S, Ikeda K, Yamanaka O, Sato M, Muragaki Y, Ohnishi Y, et al. Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice. Lab Invest. 2004;84(10):1259-70.
23. Mallawaarachchi CM, Weissberg PL, Siow RC. Smad7 gene transfer attenuates adventitial cell migration and vascular remodeling after balloon injury. Arterioscler Thromb Vasc Biol. 2005;25(7):1383-7.
24. Huang J, Wei C, Peng J, Zheng Z, Peng X. The effects of signal protein Smads on rat cardiocyte hypertrophy. J US-Chin Med Sci. 2005;2(1):29-44.
25. Jones JA, Barbour JR, Stroud RE, Bouges S, Stephens SL, Spinale FG, et al. Altered transforming growth factor-ß signaling in a murine model of thoracic aortic aneurysm. J Vasc Res. 2008;45(6):457-68.
26. Rodríguez-Vita J, Sánchez-López E, Esteban V, Rupérez M, Egido J, Ruiz-Ortega M. Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-ß-independent mechanism. Circulation. 2005;111(19):2509-17.
27. Costello I, Biondi CA, Taylor JM, Bikoff EK, Robertson EJ. Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol. 2009;9:54.
28. 1 and fibronectin. Lab Invest. 1989;60(6):755-65.
29. 1 during repair of arterial injury. J Clin Invest. 1991;88(3):904-10.
30. 1 concentration and abdominal aortic aneurysm. Br J Surg. 2009;96(6):628-32.
31. Grainger DJ, Mosedale DE, Metcalfe JC. TGF-ß in blood: a complex problem. Cytokine Growth Factor Rev. 2000;11(1-2):133-45.
32. Yuan S, Jing H. Cardiac surgery and hypertension: a dangerous association that must be well known. Rev Bras Cir Cardiovasc. 2011;26(2):273-81.
33. Boushell LW, Kaku M, Mochida Y, Bagnell R, Yamauchi M. Immunohistochemical localization of matrixmetalloproteinase-2 in human coronal dentin. Arch Oral Biol. 2008;53(2):109-16.
34. Zhou JD, Luo CQ, Xie HQ, Nie XM, Zhao YZ, Wang SH, et al. Increased expression of heat shock protein 70 and heat shock factor 1 in chronic dermal ulcer tissues treated with laser-aided therapy. Chin Med J (Engl) 2008;121(14):1269-73.
35. Quaglino A, Salierno M, Pellegrotti J, Rubinstein N, Kordon EC. Mechanical strain induces involution-associated events in mammary epithelial cells. BMC Cell Biol. 2009;10:55.
36. Kroll TC, Wölfl S. Ranking: a closer look on globalisation methods for normalisation of gene expression arrays. Nucleic Acids Res. 2002;30(11):e50.
37. 1 stabilizes already-formed aortic aneurysms: a first approach to induction of functional healing by endovascular gene therapy. Circulation. 2005;112(7):1008-15.