메뉴 건너뛰기




Volumn 8, Issue 4, 2011, Pages 260-265

Does contractility modulation have a role in the treatment of heart failure?

Author keywords

Anaerobic threshold; Cardiac contractility modulation; Cardiac resynchronization therapy; Ejection fraction; Heart failure; Myocardial infarction; Peak VO2; Prevention; Quality of life; Refractory period

Indexed keywords

ARTICLE; CLINICAL TRIAL (TOPIC); EXERCISE TOLERANCE; GENE EXPRESSION; HEART FAILURE; HEART MUSCLE BIOPSY; HEART MUSCLE CONTRACTILITY; HEART MUSCLE REFRACTORY PERIOD; HUMAN; PROTEIN PHOSPHORYLATION; QUALITY OF LIFE;

EID: 81355161559     PISSN: 15469530     EISSN: 15469549     Source Type: Journal    
DOI: 10.1007/s11897-011-0067-3     Document Type: Article
Times cited : (5)

References (36)
  • 3
    • 70349625757 scopus 로고    scopus 로고
    • Cardiac-resynchronization therapy for the prevention of heart-failure events
    • 19723701 10.1056/NEJMoa0906431
    • AJ Moss WJ Hall DS Cannom, et al. 2009 Cardiac-resynchronization therapy for the prevention of heart-failure events N Engl J Med 361 1329 38 19723701 10.1056/NEJMoa0906431
    • (2009) N Engl J Med , vol.361 , pp. 1329-38
    • Moss, A.J.1    Hall, W.J.2    Cannom, D.S.3
  • 4
    • 37249061691 scopus 로고    scopus 로고
    • Cardiac-Resynchronization Therapy in Heart Failure with Narrow QRS Complexes
    • Beshai JF, Grimm RA, Nagueh SF, et al.: Cardiac-Resynchronization Therapy in Heart Failure with Narrow QRS Complexes. N Engl J Med 2007.
    • (2007) N Engl J Med
    • Beshai, J.F.1    Grimm, R.A.2    Nagueh, S.F.3
  • 7
    • 34548232713 scopus 로고    scopus 로고
    • First use of cardiac contractility modulation (CCM) in a patient failing CRT therapy: Clinical and technical aspects of combined therapies
    • DOI 10.1016/j.ejheart.2007.05.012, PII S1388984207002462
    • C Butter J Meyhofer M Seifert, et al. 2007 First use of cardiac contractility modulation (CCM) in a patient failing CRT therapy: clinical and technical aspects of combined therapies Eur J Heart Fail 9 955 8 17597000 10.1016/j.ejheart.2007.05.012 (Pubitemid 47332313)
    • (2007) European Journal of Heart Failure , vol.9 , Issue.9 , pp. 955-958
    • Butter, C.1    Meyhofer, J.2    Seifert, M.3    Neuss, M.4    Minden, H.-H.5
  • 8
    • 56749169397 scopus 로고    scopus 로고
    • Cardiac contractility modulation in non-responders to cardiac resynchronization therapy
    • 18776196 10.1093/europace/eun257 1:STN:280:DC%2BD1cjkvFCitA%3D%3D
    • H Nagele S Behrens C Eisermann 2008 Cardiac contractility modulation in non-responders to cardiac resynchronization therapy Europace 10 1375 80 18776196 10.1093/europace/eun257 1:STN:280:DC%2BD1cjkvFCitA%3D%3D
    • (2008) Europace , vol.10 , pp. 1375-80
    • Nagele, H.1    Behrens, S.2    Eisermann, C.3
  • 9
    • 0014478314 scopus 로고
    • Inotropic effects of electric currents: 1. Positive and negative effects of constant electric currents or current pulses applied during cardiac action potential
    • 5766519 1:STN:280:DyaF1M7hsl2hug%3D%3D
    • EH Wood RL Heppner S Weidmann 1969 Inotropic effects of electric currents: 1. Positive and negative effects of constant electric currents or current pulses applied during cardiac action potential Circ Res 24 409 45 5766519 1:STN:280:DyaF1M7hsl2hug%3D%3D
    • (1969) Circ Res , vol.24 , pp. 409-45
    • Wood, E.H.1    Heppner, R.L.2    Weidmann, S.3
  • 10
    • 0014478314 scopus 로고
    • Inotropic effects of electric currents: 2. Hypotheses: Calcium movements, excitation-contraction coupling and inotropic effects
    • 5766519 1:STN:280:DyaF1M7hsl2hug%3D%3D
    • EH Wood RL Heppner S Weidmann 1969 Inotropic effects of electric currents: 2. Hypotheses: calcium movements, excitation-contraction coupling and inotropic effects Circ Res 24 409 45 5766519 1:STN:280:DyaF1M7hsl2hug%3D%3D
    • (1969) Circ Res , vol.24 , pp. 409-45
    • Wood, E.H.1    Heppner, R.L.2    Weidmann, S.3
  • 11
    • 0014441290 scopus 로고
    • Mechanical response of the frog and mammalian myocardium to changes in the action potential duration by constant current pulses
    • 4975967 10.1007/BF00586610 1:STN:280:DyaF1M7ls1Chtw%3D%3D
    • H Antoni R Jacob R Kaufmann 1969 Mechanical response of the frog and mammalian myocardium to changes in the action potential duration by constant current pulses Pflugers Arch 306 33 57 4975967 10.1007/BF00586610 1:STN:280:DyaF1M7ls1Chtw%3D%3D
    • (1969) Pflugers Arch , vol.306 , pp. 33-57
    • Antoni, H.1    Jacob, R.2    Kaufmann, R.3
  • 12
    • 0015086918 scopus 로고
    • Mechanical response of the mammalian myocardium to modifications of the action potential
    • Kaufmann RL, Antoni H, Hennekes R, et al.: Mechanical response of the mammalian myocardium to modifications of the action potential. Cardiovasc Res 1971; 1:Suppl-70.
    • (1971) Cardiovasc Res , vol.1 , Issue.SUPPL. 70
    • Kaufmann, R.L.1    Antoni, H.2    Hennekes, R.3
  • 13
    • 2342542506 scopus 로고    scopus 로고
    • Initial Interactions in Electromagnetic Field-Induced Biosynthesis
    • DOI 10.1002/jcp.20004
    • M Blank R Goodman 2004 Initial interactions in electromagnetic field-induced biosynthesis J Cell Physiol 199 359 63 15095282 10.1002/jcp.20004 1:CAS:528:DC%2BD2cXjvVOqsb8%3D (Pubitemid 38580431)
    • (2004) Journal of Cellular Physiology , vol.199 , Issue.3 , pp. 359-363
    • Blank, M.1    Goodman, R.2
  • 16
    • 0036087223 scopus 로고    scopus 로고
    • Cardiac contractility modulation by electric currents applied during the refractory period
    • 11959626 1:CAS:528:DC%2BD38XjslWmsbo%3D
    • S Mohri KL He M Dickstein, et al. 2002 Cardiac contractility modulation by electric currents applied during the refractory period Am J Physiol Heart Circ Physiol 282 H1642 H1647 11959626 1:CAS:528:DC%2BD38XjslWmsbo%3D
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Mohri, S.1    He, K.L.2    Dickstein, M.3
  • 19
    • 34248645944 scopus 로고    scopus 로고
    • Therapy With Cardiac Contractility Modulation Electrical Signals Improves Left Ventricular Function and Remodeling in Dogs With Chronic Heart Failure
    • DOI 10.1016/j.jacc.2006.10.082, PII S0735109707009138
    • •• Imai M, Rastogi S, Gupta RC, et al.: Therapy with cardiac contractility modulation electrical signals improves left ventricular function and remodeling in dogs with chronic heart failure. J Am Coll Cardiol 2007; 49:2120-8. This paper describes the results of a detailed study of the biochemical and molecular effects of CCM in an established model of heart failure. The results demonstrate the relatively rapid primary effects on phosphorylation, gene expression, and protein content in the vicinity of the signal delivery and the presumed secondary effects on remote areas that are observed within a 3-month timeframe. (Pubitemid 46771049)
    • (2007) Journal of the American College of Cardiology , vol.49 , Issue.21 , pp. 2120-2128
    • Imai, M.1    Rastogi, S.2    Gupta, R.C.3    Mishra, S.4    Sharov, V.G.5    Stanley, W.C.6    Mika, Y.7    Rousso, B.8    Burkhoff, D.9    Ben-Haim, S.10    Sabbah, H.N.11
  • 20
    • 72049110815 scopus 로고    scopus 로고
    • Impact of cardiac contractility modulation on left ventricular global and regional function and remodeling
    • •• Yu CM, Chan JY, Zhang Q, et al.: Impact of cardiac contractility modulation on left ventricular global and regional function and remodeling. JACC Cardiovasc Imaging 2009; 2:1341-9. This study shows that CCM treatment for 3 months induces reverse ventricular remodeling, manifest as reduction in end-systolic and end-diastolic size and improved ejection fraction.
    • (2009) JACC Cardiovasc Imaging , vol.2 , pp. 1341-1349
    • Yu, C.M.1    Chan, J.Y.2    Zhang, Q.3
  • 21
    • 42949104459 scopus 로고    scopus 로고
    • Cardiac Contractility Modulation Electrical Signals Improve Myocardial Gene Expression in Patients With Heart Failure
    • DOI 10.1016/j.jacc.2008.01.036, PII S073510970800692X
    • •• Butter C, Rastogi S, Minden HH, et al.: Cardiac contractility modulation electrical signals improve myocardial gene expression in patients with heart failure. J Am Coll Cardiol 2008; 51:1784-9. This myocardial biopsy study confirms that 3 months of CCM therapy in patients with heart failure induces reverse molecular remodeling and drives the genotype from the abnormal fetal program characteristic of heart failure to a more normal adult profile. Interestingly, the magnitude of changes in gene expression correlated with clinical effectiveness, as quantified by exercise tolerance and quality-of-life scores. (Pubitemid 351608495)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.18 , pp. 1784-1789
    • Butter, C.1    Rastogi, S.2    Minden, H.-H.3    Meyhofer, J.4    Burkhoff, D.5    Sabbah, H.N.6
  • 22
    • 33947535438 scopus 로고    scopus 로고
    • Enhanced Inotropic State of the Failing Left Ventricle by Cardiac Contractility Modulation Electrical Signals Is Not Associated With Increased Myocardial Oxygen Consumption
    • DOI 10.1016/j.cardfail.2006.11.004, PII S1071916406012309
    • C Butter E Wellnhofer M Schlegl, et al. 2007 Enhanced inotropic state of the failing left ventricle by cardiac contractility modulation electrical signals is not associated with increased myocardial oxygen consumption J Card Fail 13 137 42 17395055 10.1016/j.cardfail.2006.11.004 (Pubitemid 46467396)
    • (2007) Journal of Cardiac Failure , vol.13 , Issue.2 , pp. 137-142
    • Butter, C.1    Wellnhofer, E.2    Schlegl, M.3    Winbeck, G.4    Fleck, E.5    Sabbah, H.N.6
  • 23
  • 28
    • 79851468796 scopus 로고    scopus 로고
    • A randomized controlled trial evaluating the safety and efficacy of cardiac contractility modulation in advanced heart failure
    • 2 was about 0.7 mL/kg/min greater in the treatment group compared to the control group. The primary safety end point of the study was met. The analysis revealed a subgroup of patients with particularly good response that now is being analyzed in a new study being conducted in the United States.
    • (2011) Am Heart J , vol.161 , pp. 329-37
    • Kadish, A.1    Nademanee, K.2    Volosin, K.3
  • 29
    • 52949139748 scopus 로고    scopus 로고
    • A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation in patients with systolic heart failure: Rationale, design, and baseline patient characteristics
    • This article provides a detailed description of the methodology and rationale for the United States study design. Several anticipated difficulties of the study were discussed in detail.
    • • Abraham WT, Burkhoff D, Nademanee K, et al.: A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation in patients with systolic heart failure: rationale, design, and baseline patient characteristics. Am Heart J 2008; 156:641-8. This article provides a detailed description of the methodology and rationale for the United States study design. Several anticipated difficulties of the study were discussed in detail.
    • (2008) Am Heart J , vol.156 , pp. 641-648
    • Abraham, W.T.1    Burkhoff, D.2    Nademanee, K.3
  • 30
    • 72749098356 scopus 로고    scopus 로고
    • The ventilatory anaerobic threshold in heart failure: A multicenter evaluation of reliability
    • This article provides a detailed analysis of the United States study data highlighting the difficulties in using the anaerobic threshold as a primary study end point
    • • Myers J, Goldsmith RL, Keteyian SJ, et al.: The ventilatory anaerobic threshold in heart failure: a multicenter evaluation of reliability. J Card Fail 2010; 16:76-83. This article provides a detailed analysis of the United States study data highlighting the difficulties in using the anaerobic threshold as a primary study end point.
    • (2010) J Card Fail , vol.16 , pp. 76-83
    • Myers, J.1    Goldsmith, R.L.2    Keteyian, S.J.3
  • 32
    • 38349098526 scopus 로고    scopus 로고
    • Impact of cardiac resynchronization therapy on exercise performance, functional capacity, and quality of life in systolic heart failure with QRS prolongation: COMPANION trial sub-study
    • 18226768 10.1016/j.cardfail.2007.08.003
    • T De Marco E Wolfel AM Feldman, et al. 2008 Impact of cardiac resynchronization therapy on exercise performance, functional capacity, and quality of life in systolic heart failure with QRS prolongation: COMPANION trial sub-study J Card Fail 14 9 18 18226768 10.1016/j.cardfail.2007.08.003
    • (2008) J Card Fail , vol.14 , pp. 9-18
    • De Marco, T.1    Wolfel, E.2    Feldman, A.M.3
  • 33
    • 0034888581 scopus 로고    scopus 로고
    • Clinical trials update: Highlights of the scientific sessions of heart failure 2001, a meeting of the Working Group on Heart Failure of the European Society of Cardiology. CONTAK-CD, CHRISTMAS, OPTIME-CHF
    • DOI 10.1016/S1388-9842(01)00175-1, PII S1388984201001751
    • S Thackray A Coletta P Jones, et al. 2001 Clinical trials update: Highlights of the Scientific Sessions of Heart Failure 2001, a meeting of the Working Group on Heart Failure of the European Society of Cardiology. CONTAK-CD, CHRISTMAS, OPTIME-CHF Eur J Heart Fail 3 491 4 11511436 10.1016/S1388-9842(01) 00175-1 1:STN:280:DC%2BD3Mvms1ClsQ%3D%3D (Pubitemid 32780527)
    • (2001) European Journal of Heart Failure , vol.3 , Issue.4 , pp. 491-494
    • Thackray, S.1    Coletta, A.2    Jones, P.3    Dunn, A.4    Clark, A.L.5    Cleland, J.G.F.6
  • 36
    • 60649088431 scopus 로고    scopus 로고
    • Effects of cardiac resynchronization therapy on long-term quality of life: An analysis from the CArdiac Resynchronisation-Heart Failure (CARE-HF) study
    • 19249415 10.1016/j.ahj.2008.11.006
    • JG Cleland MJ Calvert Y Verboven N Freemantle 2009 Effects of cardiac resynchronization therapy on long-term quality of life: an analysis from the CArdiac Resynchronisation-Heart Failure (CARE-HF) study Am Heart J 157 457 66 19249415 10.1016/j.ahj.2008.11.006
    • (2009) Am Heart J , vol.157 , pp. 457-66
    • Cleland, J.G.1    Calvert, M.J.2    Verboven, Y.3    Freemantle, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.