Influence of elastin-derived peptides, glucose, LDL and oxldl on nitric oxide synthase expression in human umbilical artery endothelial cells

Acta Biochimica Polonica

Volumn 58, Issue 3, 2011, Pages 375-379

  Garczorz, Wojciech ^a   Francuz, Tomasz ^a   Gmiński, Jan ^a   Likus, Wirginia ^a   Siemianowicz, Krzysztof ^a   Jurczak, Teresa ^a   Strzałka Mrozik, Barbara ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Atherosclerosis; Edp; Elastin derived peptides; Endothelium; Enos; Hyperglycemia; Ldl; Nitric oxide synthase; Oxidized LDL

Indexed keywords

EID: 81355139519     PISSN: 0001527X     EISSN: 1734154X     Source Type: Journal    
DOI: 10.18388/abp.2011_2249     Document Type: Article

References (22)

1. Braam B, Verhaar MC (2007) Understanding eNOS for pharmacological modulation of endothelial function: a translational view. Curr Pharm Des 13: 1727-1740.
2. Cai H, Harrison DG (2000) Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87: 840-844.
3. Cosentino F, Hishikawa K, Katusic ZS, Luscher TF (1997) High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96: 25-28.
4. Dötsch J, Hogen N, Nyúl Z, Hänze J, Knerr I, Kirschbaum M, Rascher W (2001) Increase of endothelial nitric oxide synthase and endothelin-1 mRNA expression in human placenta during gestation. Eur J Obstet Gynecol Reprod Biol 97: 163-167.
5. Faury G, Ristori MT, Verdetti J, Jacob MP, Robert L (1995) Effect of elastin peptides on vascular tone. J Vasc Res 32: 112-119.
6. 2+ level in human vascular endothelial cells. Circ Res 82: 328-336.
7. Fulop T Jr, Wei SM, Robert L, Jacob MP (1990) Determination of elastin peptides in normal and arteriosclerotic human sera by ELISA. Clin Physiol Biochem 8: 273-282.
8. Fulop T Jr, Larbi A, Fortun A, Robert L, Khalil A (2005) Elastin peptides induced oxidation of LDL by phagocytic cells. Pathol Biol (Paris) 53: 416-423.
9. Galle J, Wanner C (1998) Oxidized LDL and Lp(a). Preparation, modification, and analysis. Methods Mol Biol 108: 119-130.
10. Garland J (2002) Isolation of LDL (low density lipoprotein) from human plasma. www.protocol-online.org 2002; access: 15 May 2010 http://www.protocol-online.org/cgi-bin/prot/view_cache.cgi?ID=2520
11. Gmiński J, Dróżdż M (1991) Succinyl trialanine p-nitroanilide hydrolytic activities in plasma and the aorta of rabbits experimentally immunized with soluble elastin. Exp Pathol 43: 37-40.
12. Gmiński J, Dróżdż M, Ulfig-Maślanka R, Najda J (1991) Evaluation of elastin metabolism in children from families with high risk of atherosclerosis. Atherosclerosis 91: 185-189.
13. Hornebeck W, Robert L (1977) Elastase-like enzymes in aortas and human brest carcinomas: quantitative variations with age and pathology. Adv Exp Med Biol 79: 145-156.
14. Jiménez A, Arriero MM, López-Blaya A, González-Fernandez F, García R, Fortes J, Millás I, Velasco S, Sánchez De Miguel L, Rico L, Farré J, Casado S, López-Farré A (2001) Regulation of endothelial nitric oxide synthase expression in the vascular wall and in mononuclear cells from hypercholesterolemic rabbits. Circulation 104: 1822-1830.
15. Liao JK, Shin WS, Lee WY, Clark SL (1995) Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase. J Biol Chem 270: 319-324.
16. Liaudet L, Vassalli G, Pacher P (2009) Role of peroxynitrite in the redox regulation of cell signal transduction pathways. Front Biosci 14: 4809-4814.
17. Ogut O, Brozovich FV (2008) The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure. J Cell Mol Med 12: 2158-2164.
18. Pritchard KA, Ackerman AW, Ou J, Curtis M, Smalley DM, Fontana JT, Stemerman MB, Sessa WC (2002) Native low-density lipoprotein induces endothelial nitric oxide synthase dysfunction: role of heat shock protein 90 and caveolin-1. Free Radic Biol Med 33: 52-62.
19. Robert L, Labat-Robert J, Robert AM (2010) Genetic, epigenetic and posttranslational mechanisms of aging. Biogerontology DOI: 10.1007/ s10522-010-9262-y.
20. Ross R (1999) Atherosclerosis - an inflammatory disease. N Engl J Med 340: 115-126.
21. Srinivasan S, Hatley ME, Bolick DT, Palmer LA, Edelstein D, Brownlee M, Hedrick CC (2004) Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells. Diabetologia 47: 1727-1734.
22. Stone NJ, Bilek S, Rosenbaum S (2005) Recent National Cholesterol Education Program Adult Treatment Panel III update: adjustments and options. Am J Cardiol 96: 53E-59E.