Fibroblast growth factor-21 mediates hepatic glucose metabolism of type 1 diabetes model and its mechanism

Progress in Biochemistry and Biophysics

Volumn 38, Issue 10, 2011, Pages 953-960

  Sun, Guo Peng ^a   Ye, Xian Long ^b   Ren, Gui Ping ^b   Li, Jin Nan ^b   Li, De Shan ^b  

^a XINXIANG UNIVERSITY   (China)

^b NORTHEAST AGRICULTURAL UNIVERSITY   (China)

Author keywords

Diabetes therapeutic agent; Fibroblast growth factor 21; Glucose metabolic; Slow onset type 1 diabetes animal model; Synergy effect with insulin

Indexed keywords

ANIMALIA; MUS;

EID: 81355133717     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2011.00098     Document Type: Article

References (14)

1. Moller D E. New drug targets for type 2 diabetes and the metabolic syndrome. Nature, 2001, 414(6865): 821-827 (Pubitemid 34000786)
2. Kharitonenkov A, Dunbar J D, Bina H A, et al. FGF-21/FGF-21 receptor interaction and activation is determined by beta Klotho. Cell Physiol, 2008, 215(1): 1-7 (Pubitemid 351363185)
3. Wente W, Efanov A M, Brenner M, et al. Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways. Diabetes, 2006, 55(9): 2470-2478 (Pubitemid 44871147)
4. Liu MY, Wang WF, Yu Y X, et al. Prog Biochem Biophys, 2009, 36(10): 1327-1333
5. Zhang J T, Bao T Y, Cao E H, et al. Modern Experimental Methods In Pharmacology(Volume 1, 2). Beijing: Peking University Medical Press, 1997: 984-985
6. Liu J L, Li L, Yang G Y. Lab Med Clin, 2007, 4(7): 642-643
7. Wang WF, Li X K, Li D S. Chin PharmBull, 2009, 25(4): 433-435
8. Jiang Y Y, Liu MY, Ren G P, et al. Prog Biochem Biophys, 2009, 36(2): 157-164
9. Li J N, Liu MY, Hou Y T, et al. Chin J Biochem Mol Biol, 2009, 25(6): 556-562
10. Postic C, Dentin R, Girard J, et al. Role of the liver in the control of carbohydrate and lipid homeostasis. Diabetes Metab, 2004, 30(5): 398-408 (Pubitemid 39648006)
11. Kayano T, Burant C F, Fukumoto H, et al. Human facilitative glucose transporters. J Biol Chem, 1990, 265(22): 13276-13282
12. Takata K, Kasahara T, Kasahara M, et al. Erythrocyte/HepG2-type glucose transporter is concentrated in cells of blood-tissue barriers. BiochemBiophys Res Commun, 1990, 173(1): 67-73
13. Zhao F Q, Glimm D R, Kennelly J J, et al. Distribution of mammalian facultative glucose tranporter messenger RNA in bovine tissues. Int J Biochem, 1993, 25(12): 1897-1903
14. Hosake T, Brooks C C, Presman E, et al. p115 interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation. Mol Biol Cell, 2005, 16(6): 2882-2890 (Pubitemid 40741232)