Partition constant and volume of distribution as predictors of clinical efficacy of lipid rescue for toxicological emergencies

Clinical Toxicology

Volumn 49, Issue 9, 2011, Pages 801-809

  French, Deborah ^a   Smollin, Craig ^a   Ruan, Weiming ^a   Wong, Alicia ^a   Drasner, Kenneth ^a   Wu, Alan H B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Drug overdose; Drug properties; Lipid emulsion therapy

Indexed keywords

AMFEBUTAMONE; AMITRIPTYLINE; BUPIVACAINE; HALOPERIDOL; INTRALIPID; LAMOTRIGINE; MEPIVACAINE; QUETIAPINE; ROPIVACAINE; SERTRALINE; VERAPAMIL; ZOLPIDEM;

ARTICLE; DRUG BINDING; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PARTITION COEFFICIENT; SERUM; SOLID PHASE EXTRACTION; STATISTICAL MODEL; ULTRACENTRIFUGATION;

EMERGENCIES; EMULSIONS; FAT EMULSIONS, INTRAVENOUS; HUMANS; MODELS, STATISTICAL; OVERDOSE; PHARMACEUTICAL PREPARATIONS; PHOSPHOLIPIDS; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; SOYBEAN OIL;

EID: 81255214420     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2011.617308     Document Type: Article

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