Nytt genkart for multippel sklerose

Tidsskrift for den Norske Laegeforening

Volumn 131, Issue 21, 2011, Pages 2126-2130

  Harbo, Hanne F ^a,b   Lorentzen, Åslaug R ^a,d   Lie, Benedicte A ^b,c   Celius, Elisabeth Gulowsen ^a   Spurkland, Anne ^b  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d Vågsbygd legesenter   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN;

ADULT; ARTICLE; ENVIRONMENTAL EXPOSURE; GENE LOCUS; GENETIC ASSOCIATION; GENETICS; HUMAN; IMMUNOLOGY; MULTIPLE SCLEROSIS; RISK FACTOR;

ADULT; ENVIRONMENTAL EXPOSURE; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; HLA-A ANTIGENS; HUMANS; MULTIPLE SCLEROSIS; RISK FACTORS;

EID: 81255209216     PISSN: 00292001     EISSN: 08077096     Source Type: Journal    
DOI: 10.4045/tidsskr.10.0823     Document Type: Article

References (57)

1. Ramagopalan SV, Knight JC, Ebers GC. Multiple sclerosis and the major histocompatibility complex. Curr Opin Neurol 2009; 22: 219-25.
2. Hafler DA, Compston A, Sawcer S et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 2007; 357: 851-62.
3. Sawcer S, Hellenthal G, Pirinen M et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011; 476: 214-9.
4. Río J, Comabella M, Montalban X. Multiple sclerosis: current treatment algorithms. Curr Opin Neurol 2011; 24: 230-7.
5. Smestad C, Sandvik L, Holmoy T et al. Marked differences in prevalence of multiple sclerosis between ethnic groups in Oslo, Norway. J Neurol 2008; 255: 49-55.
6. Harbo HF, Utsi E, Lorentzen AR et al. Low frequency of the disease-associated DRB1*15-DQB1*06 haplotype may contribute to the low prevalence of multiple sclerosis in Sami. Tissue Antigens 2007; 69: 299-304.
7. Celius EG, Smestad C. Change in sex ratio, disease course and age at diagnosis in Oslo MS patients through seven decades. Acta Neurol Scand Suppl 2009; 120: 27-9.
8. Ebers GC. A twin consensus in MS. Mult Scler 2005; 11: 497-9.
9. Hammond SR, English DR, McLeod JG. The agerange of risk of developing multiple sclerosis: evidence from a migrant population in Australia. Brain 2000; 123: 968-74.
10. Hayes CE, Cantorna MT, DeLuca HF. Vitamin D and multiple sclerosis. Proc Soc Exp Biol Med 1997; 216: 21-7.
11. Munger KL, Levin LI, Hollis BW et al. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA 2006; 296: 2832-8.
12. Ahlgren C, Torén K, Odén A et al. A populationbased case-control study on viral infections and vaccinations and subsequent multiple sclerosis risk. Eur J Epidemiol 2009; 24: 541-52.
13. Ascherio A, Munger KL. Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors. Ann Neurol 2007; 61: 504-13.
14. Jersild C, Svejgaard A, Fog T. HL-A antigens and multiple sclerosis. Lancet 1972; 1: 1240-1.
15. Naito S, Namerow N, Mickey MR et al. Multiple sclerosis: association with HL-A3. Tissue Antigens 1972; 2: 1-4.
16. McFarland HF, Martin R. Multiple sclerosis: a complicated picture of autoimmunity. Nat Immunol 2007; 8: 913-9.
17. Jersild C, Fog T, Hansen GS et al. Histocompatibility determinants in multiple sclerosis, with special reference to clinical course. Lancet 1973; 2: 1221-5.
18. Olerup O, Hillert J. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens 1991; 38: 1-15.
19. Dyment DA, Herrera BM, Cader MZ et al. Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet 2005; 14: 2019-26.
20. Lincoln MR, Ramagopalan SV, Chao MJ et al. Epistasis among HLA-DRB1, HLA-DQA1, and HLADQB1 loci determines multiple sclerosis susceptibility. Proc Natl Acad Sci U S A 2009; 106: 7542-7.
21. Brynedal B, Duvefelt K, Jonasdottir G et al. HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis. PLoS ONE 2007; 2: e664.
22. Harbo HF, Lie BA, Sawcer S et al. Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis. Tissue Antigens 2004; 63: 237-47.
23. Yeo TW, De Jager PL, Gregory SG et al. A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol 2007; 61: 228-36.
24. De Jager PL, Jia X, Wang J et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet 2009; 41: 776-82.
25. Lorentzen AR, Karlsen TH, Olsson M et al. Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis. Ann Neurol 2009; 65: 658-66.
26. Rolstad B, Vaage JT, Naper C et al. Positive and negative MHC class I recognition by rat NK cells. Immunol Rev 1997; 155: 91-104.
27. Naper C, Ryan JC, Nakamura MC et al. Identification of an inhibitory MHC receptor on alloreactive rat natural killer cells. J Immunol 1998; 160: 219-24.
28. Dupont WD, Plummer WD Jr. Power and sample size calculations. A review and computer program. Control Clin Trials 1990; 11: 116-28.
29. Sawcer S. A new era in the genetic analysis of multiple sclerosis. Curr Opin Neurol 2006; 19: 237-41.
30. Gasser T. Autosomal-dominantly inherited forms of Parkinson's disease. J Neural Transm Suppl 2000; nr. 58: 31-40.
31. Harbo HF, Mørk S, Vedeler C et al. Biobank for multippel sklerose etablert. Tidsskr Nor Lægeforen 2007; 127: 2276.
32. Mero IL, Lorentzen AR, Ban M et al. A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. Eur J Hum Genet 2010; 18: 502-4.
33. Mero IL, Ban M, Lorentzen AR et al. Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus. Genes Immun 2011; 12: 191-8.
34. Gregory SG, Schmidt S, Seth P et al. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet 2007; 39: 1083-91.
35. Lundmark F, Duvefelt K, Iacobaeus E et al. Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet 2007; 39: 1108-13.
36. Comabella M, Craig DW, Camiña-Tato M et al. Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms. PLoS ONE 2008; 3: e3490.
37. Aulchenko YS, Hoppenbrouwers IA, Ramagopalan SV et al. Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis. Nat Genet 2008; 40: 1402-3.
38. Baranzini SE, Wang J, Gibson RA et al. Genomewide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet 2009; 18: 767-78.
39. Bahlo M, Booth DR, Broadley SA et al. Genomewide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet 2009; 41: 824-8.
40. Jakkula E, Leppä V, Sulonen AM et al. Genomewide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet 2010; 86: 285-91.
41. Sanna S, Pitzalis M, Zoledziewska M et al. Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet 2010; 42: 495-7.
42. Weber F, Fontaine B, Cournu-Rebeix I et al. IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations. Genes Immun 2008; 9: 259-63.
43. Booth D, Heard R, Stewart G et al. Refining genetic associations in multiple sclerosis. Lancet Neurol 2008; 7: 567-9.
44. Rubio JP, Stankovich J, Field J et al. Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians. Genes Immun 2008; 9: 624-30.
45. Alcina A, Fedetz M, Ndagire D et al. IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D). PLoS ONE 2009; 4: e4137.
46. Akkad DA, Hoffjan S, Petrasch-Parwez E et al. Variation in the IL7RA and IL2RA genes in German multiple sclerosis patients. J Autoimmun 2009; 32: 110-5.
47. Alcina A, Fedetz M, Ndagire D et al. The T244I variant of the interleukin-7 receptor-alpha gene and multiple sclerosis. Tissue Antigens 2008; 72: 158-61.
48. Hoppenbrouwers IA, Aulchenko YS, Ebers GC et al. EVI5 is a risk gene for multiple sclerosis. Genes Immun 2008; 9: 334-7.
49. Hafler JP, Maier LM, Cooper JD et al. CD226 Gly307Ser association with multiple autoimmune diseases. Genes Immun 2009; 10: 5-10.
50. Ban M, Goris A, Lorentzen AR et al. Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. Eur J Hum Genet 2009; 17: 1309-13.
51. Ban M, McCauley JL, Zuvich R et al. A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis. Genes Immun 2010; 11: 660-4..
52. McCauley JL, Zuvich R, Beecham AL et al. Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Hum Mol Genet 2010; 19: 953-62.
53. Booth DR, Heard RN, Stewart GJ. The expanding genetic overlap between multiple sclerosis and type I diabetes. Genes Immun 2009; 10: 11-4.
54. Martínez A, Perdigones N, Cénit MC et al. Chromosomal region 16p13: further evidence of increased predisposition to immune diseases. Ann Rheum Dis 2010; 69: 309-11.
55. Zoledziewska M, Costa G, Pitzalis M et al. Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia. Genes Immun 2009; 10: 15-7.
56. Burton PR, Clayton DG, Cardon LR et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007; 39: 1329-37.
57. Zhernakova A, van Diemen CC, Wijmenga C. Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat Rev Genet 2009; 10: 43-55.