Hibernomas: Clinicopathological features, diagnosis, and treatment of 17 cases

Orthopedics

Volumn 34, Issue 11, 2011, Pages

  Mavrogenis, Andreas F ^a   Coll Mesa, Luis ^a   Drago, Gabriele ^a   Gambarotti, Marco ^b   Ruggieri, Pietro ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BUTTOCK; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICOPATHOLOGICAL FEATURE; DISEASE DURATION; FEMALE; FOLLOW UP; HIBERNOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFANT; LIPOMA; MALE; NECK; PAIN; PAINLESS PALPABLE MASS; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCAPULA; SCHOOL CHILD; SYMPTOM; THIGH; TUMOR LOCALIZATION; TUMOR RECURRENCE;

ADIPOCYTES, BROWN; ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; INFANT; LIPOMA; MALE; MIDDLE AGED; SOFT TISSUE NEOPLASMS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 81255205412     PISSN: 01477447     EISSN: None     Source Type: Journal    
DOI: 10.3928/01477447-20110922-12     Document Type: Article

References (40)

1. Merkel H. On a pseudolipoma of the breast (peculiar fat tumors). Beitr Pathol Anat. 1906; (39):152-157.
2. Murphey MD, Carroll JF, Flemming DJ, Pope TL, Gannon FH, Kransdorf MJ. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics. 2004; 24(5):1433-1466. (Pubitemid 39329386)
3. Miettinen MM, Fanburg-Smith JC, Mandahl N. Hibernoma. In: Fletcher CDM, Unni KK, Mertens F, eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; 2002:19-46.
4. Cantisani V, Mortele KJ, Glickman JN, et al. Large retroperitoneal hibernoma in an adult male: CT imaging findings with pathologic correlation. Abdom Imaging. 2003; 28(5):721-724. (Pubitemid 37040182)
5. Hardes J, Scheil-Bertram S, Hartwig E, Gebert C, Gosheger G, Schulte M. Sonographic findings of hibernoma. A report of two cases. J Clin Ultrasound. 2005; 33(6):298-301. (Pubitemid 41266227)
6. Nord KH, Magnusson L, Isaksson M, et al. Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma [published online ahead of print November 15, 2010]. Proc Natl Acad Sci USA. 2010; 107(49):21122-21127.
7. Baskurt E, Padgett DM, Matsumoto JA. Multiple hibernomas in a 1-month-old female infant. AJNR Am J Neuroradiol. 2004; 25(8):1443-1445. (Pubitemid 44364360)
8. Heaton JM. The distribution of brown adipose tissue in the human. J Anat. 1972; 112 (Pt. 1):35-39.
9. Merklin RJ. Growths and distribution of human fetal brown fat. Anat Rec. 1974; 178(3):637-645.
10. Furlong MA, Fanburg-Smith JC, Miettinen M. The morphologic spectrum of hibernoma: a clinicopathologic study of 170 cases. Am J Surg Pathol. 2001; 25(6):809-814. (Pubitemid 32496872)
11. Anderson SE, Schwab C, Stauffer E, Banic A, Steinbach LS. Hibernoma: imaging characteristics of a rare benign soft tissue tumor. Skeletal Radiol. 2001; 30(10):590-595. (Pubitemid 32962600)
12. Ersozlu S, Sahin O, Ozgur AF, Akkaya T. Sciatic neuropathy from a giant hibernoma of the thigh: a case report. Am J Orthop (Belle Mead NJ). 2008; 37(5):E103-106.
13. Moretti VM, de la Cruz M, Lackman RD. Recurrent lipoma-like hibernoma. Am J Orthop (Belle Mead NJ). 2010; 39(6):E57-60.
14. Lowry WS, Halmos PB. Malignant tumor of brown fat in a patient with Turner's syndrome. Br Med J. 1967; 4(5581):720-721.
15. Ahmed SA, Schuller I. Pediatric hibernoma: a case review. J Pediatr Hematol Oncol. 2008; 30(12):900-901.
16. Nigrisoli M, Ruggieri P, Picci P, Pignatti G. Case report 489: Hibernoma of left thigh. Skeletal Radiol. 1988; 17(6):432-435.
17. Nishida J, Ehara S, Shiraishi H, et al. Clinical findings of hibernoma of the buttock and thigh: rare involvements and extremely high uptake of FDG-PET. Med Sci Monit. 2009; 15(7):CS117-122.
18. Dursun M, Agayev A, Bakir B, et al. CT and MR characteristics of hibernoma: six cases. Clin Imaging. 2008; 32(1):42-47. (Pubitemid 350299118)
19. Futani H, Yamagiwa T, Yasojimat H, Natsuaki M, Stugaard M, Maruo S. Distinction between well-differentiated liposarcoma and intramuscular lipoma by power Doppler ultrasonography. Anticancer Res. 2003; 23(2C):1713-1718. (Pubitemid 36750836)
20. Cook MA, Stern M, de Silva RD. MRI of a hibernoma. J Comput Assist Tomogr. 1996; 20(2):333-335. (Pubitemid 26108727)
21. Evers LH, Gebhard M, Lange T, Siemers F, Mailänder P. Hibernoma-case report and literature review. Am J Dermatopathol. 2009; 31(7):685-686.
22. Wright C, Berry BH Jr, Patterson PJ, Griffiths HJ. Radiologic case study. Hibernoma. Orthopedics. 2003; 26(12):1194,1268-1270.
23. Saito M, Tsuji Y, Murata H, et al. Hibernoma of the right back. Orthopedics. 2007; 30(6):495-496. (Pubitemid 47082721)
24. Drevelegas A, Pilavaki M, Chourmouzi D. Lipomatous tumors of soft tissue: MR appearance with histological correlation. Eur J Radiol. 2004; 50(3):257-267. (Pubitemid 38625728)
25. Oller JD, Gómez JD, Kortazar JF, et al. Scapular hibernoma fortuitously discovered on myocardial perfusion imaging through Tc-99m tetrofosmin. Clin Nucl Med. 2001; 26(1):69-70. (Pubitemid 32003192)
26. Chatterton BE, Mensforth D, Coventry BJ, Cohen P. Hibernoma: intense uptake seen on Tc-99m tetrofosmin and FDG positron emission tomographic scanning. Clin Nucl Med. 2002; 27(5):369-370. (Pubitemid 34437684)
27. Balestreri L, Canzonieri V. Case report: axillary hibernoma-radiological and pathological findings of a rare tumour. Clin Radiol. 1998; 53(11):853-855. (Pubitemid 28517525)
28. Tomihama RT, Lindskog DM, Ahrens W, Haims AH. Hibernoma: a case report demonstrating usefulness of MR angiography in characterizing the tumor [published online ahead of print January 13, 2007]. Skeletal Radiol. 2007; 36(6):541-545. (Pubitemid 46767582)
29. Saqi A, Yu GH, Marshall MB. Fine-needle aspiration of hibernoma. Diagn Cytopathol. 2003; 29(1):44-45.
30. Lemos MM, Kindblom LG, Meis-Kindblom JM, et al. Fine-needle aspiration characteristics of hibernoma. Cancer. 2001; 93(3):206-210. (Pubitemid 32552843)
31. Enterline HT, Lowry LD, Richman AV. Does malignant hibernoma exist? Am J Surg Pathol. 1979; 3(3):265-271. (Pubitemid 9186265)
32. Gaffney EF, Hargreaves HK, Semple E, Vellios F. Hibernoma: distinctive light and electron microscopic features and relationship to brown adipose tissue. Hum Pathol. 1983; 14(8):677-687. (Pubitemid 13034268)
33. Enzinger FM, Weiss SW. Soft Tissue Tumors. London, England: CV Mosby; 1995.
34. Chirieac LR, Dekmezian RH, Ayala AG. Characterization of the myxoid variant of hibernoma. Ann Diagn Pathol. 2006; 10(2):104-106.
35. Rigor VU, Goldstone SE, Jones J, Bernstein R, Gold MS, Weiner S. Hibernoma. A case report and discussion of a rare tumor. Cancer. 1986; 57(11):2207-2211. (Pubitemid 16121758)
36. Gómez Sotelo AI, Caba Molina M, Romera López AL, Pérez Ramón JA, Rodríguez Morillas D. Retroperitoneal hibernoma [in Spanish] [published online ahead of print April 8, 2010]. Cir Esp. 2010; 88(5):345-346.
37. Lee JC, Gupta A, Saifuddin A, et al. Hibernoma: MRI features in eight consecutive cases. Clin Radiol. 2006; 61(12):1029-1034. (Pubitemid 44767128)
38. Florio G, Cicia S, Del Papa M, Carnì D. Neck hibernoma: case report and literature review. G Chir. 2000; 21(8-9):339-341.
39. Hall RE, Kooning J, Hartman L, DelBalso A. Hibernoma: an unusual tumor of adipose tissue. Oral Surg Oral Med Oral Pathol. 1988; 66(6):706-710. (Pubitemid 19019649)
40. Lele SM, Chundru S, Chaljub G, Adegboyega P, Haque AK. Hibernoma: a report of 2 unusual cases with a review of the literature. Arch Pathol Lab Med. 2002; 126(8):975-978.