A review of the methods, interpretation, and limitations of the urine drug screen

Orthopedics

Volumn 34, Issue 11, 2011, Pages 877-881

  Markway, E Claire ^a   Baker, Stephanie N ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; AMPHETAMINE; BARBITURIC ACID DERIVATIVE; CANNABINOID; CHLORPROMAZINE; CLOMIFENE; COCAINE; DEXTROMETHORPHAN; DIPHENHYDRAMINE; DOXYLAMINE; DRONABINOL; EFAVIRENZ; FENOPROFEN; GATIFLOXACIN; IBUPROFEN; ILLICIT DRUG; IMIPRAMINE; KETAMINE; METHADONE; METHAMPHETAMINE; NAPROXEN; NON PRESCRIPTION DRUG; OFLOXACIN; PHENCYCLIDINE; PRESCRIPTION DRUG; QUETIAPINE; RIFAMPICIN; THIORIDAZINE; UNINDEXED DRUG; VERAPAMIL;

DRUG DEPENDENCE; DRUG METABOLISM; DRUG OVERDOSE; DRUG URINE LEVEL; EMERGENCY HEALTH SERVICE; FALSE POSITIVE RESULT; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOASSAY; LEGAL ASPECT; QUALITATIVE ANALYSIS; REFERENCE VALUE; REVIEW; SCREENING TEST; TOXICOLOGY; URINALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLINICAL LABORATORY TECHNIQUES; DIAGNOSTIC ERRORS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; IMMUNOASSAY; OVERDOSE; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; SUBSTANCE ABUSE DETECTION; URINALYSIS;

EID: 81255189470     PISSN: 01477447     EISSN: None     Source Type: Journal    
DOI: 10.3928/01477447-20110922-22     Document Type: Review

References (22)

1. Tintinalli JE, Kelen GD, Stapczynski JS. Toxicology and pharmacology. In: Emergency Medicine: A Comprehensive Study Guide. 6th ed. Columbus, OH: McGraw-Hill; 2006:1015-1174.
2. Rainey PM, Nelson LS, Goldfrank NE, et al. Goldfrank's Toxicologic Emergencies, 9e. Chapter 6: Laboratory Principles. http://www. accessemergencymedicine.com/content.aspx?aID=6502905.
3. Moeller KE, Lee KC, Kissack JC. Urine drug screening: practical guide for clinicians. Mayo Clin Proc. 2008; 83(1): 66-76.
4. Verstraete AG. Detection times of drugs of abuse in blood, urine, and oral fluid. Ther Drug Monit. 2004; 26(2):200-205. (Pubitemid 38501218)
5. Woelfel JA. Drug abuse urine tests: false-positive results. Pharmacist Lett/Prescribers Lett. 2005; 21(3):210-314.
6. Brahm NC, Yeager LL, Fox MD, Farmer KC, Palmer TA. Commonly prescribed medications and potential falsepositive drug screens. Am J Health Syst Pharm. 2010; 67(16):1344-1350.
7. Standridge JB, Adams SM, Zotos AP. Urine drug screening: a valuable office procedure. Am Fam Physician. 2010; 81(5): 635-640.
8. Tenenbein M. Do you really need that emergency drug screen? Clin Toxicol (Phila). 2009; 47(4): 286-291.
9. Chou R, Fanciullo GJ, Fine PG, Miaskowski C, Passik SD, Portenoy RK. Opioids for chronic noncancer pain: prediction and identification of aberrant drug-related behaviors: a review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline. J Pain. 2010; 10(2):131-146.
10. Starrels JL, Becker WC, Alford DP, Kapoor A, Williams AR, Turner BJ. Systematic review: treatment agreements and urine drug testing to reduce opioid misuse in patients with chronic pain. Ann Intern Med. 2010; 152(11):712-720.
11. US Department of Health and Human Services. Mandatory guidelines and proposed revisions to mandatory guidelines for federal workplace drug testing programs: notices. Federal Register. April 13, 2004;69(71):19659-19660. http://ncadistore.samhsa.gov/catalog/ProductDetails.aspx?ProductID=16833. Accessed October 4, 2011.
12. Kelly KL. Ranitidine cross-reactivity in the EMIT d.a.u. monoclonal amphetamine/ methamphetamine assay. Clin Chem. 1990; 36(7):1391-1392. (Pubitemid 20251964)
13. Huang BC, Lien MH, Wang PY, et al. Interference by drugs contained in over-the-counter cold syrups on methamphetamine immunoassay test kits used in drug abuse assessment. J Food Drug Anal. 1995; (34):259-268.
14. Rollins DE, Jennison TA, Jones G. Investigation of interference by nonsteroidal anti-inflammatory drugs in urine tests for abused drugs. Clin Chem. 1990; 36(4):602-606.
15. Oxaprozin [package insert]. Princeton, NJ: Sandoz Inc; 2007.
16. Green KB, Isenschmid DS. Medical review officer interpretation of urine drug testing results. Forensic Sci Rev. 1995; (7):41-60.
17. Greenblatt DJ, Shader RI. Pharmacokinetics of antianxiety agents. In: Meltzer H, ed. Psychopharmacology: The Third Generation of Progress. New York, NY: Raven Press; 1987:1377-1386.
18. Fentanyl [package insert]. Titusville, NJ: Janssen Pharma LP; 2003.
19. OxyContin [package insert]. Stamford, CT: Purdue Pharma LP; 2007.
20. Sue Y, Shannon M. Pharmacokinetics of drugs in overdose. Clin Pharmacokinet. 1992; 23(2):93-105.
21. Marik P, Varon J. The obese patient in the ICU. Chest. 1998; 113(2):492-498. (Pubitemid 28110029)
22. Bodenham A, Shelly MP, Park GR. The altered pharmacokinetics and pharmacodynamics of drugs commonly used in critically ill patients. Clin Pharmacokinet. 1988; 14(6):347-373.