Altered matrix at the chondro-osseous junction leads to defects in lymphopoiesis

Annals of the New York Academy of Sciences

Volumn 1237, Issue 1, 2011, Pages 79-87

  Sweeney, Elizabeth ^a   Roberts, Douglas ^a   Jacenko, Olena ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

B lymphocytes; Bone marrow; Endochondral ossification; Extracellular matrix; Hematopoiesis; Hematopoietic niche

Indexed keywords

COLLAGEN TYPE 10; GLYPICAN;

ARTICLE; CARTILAGE CELL; HEMATOPOIETIC CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOPOIESIS; OSTEOBLAST; TRABECULAR BONE;

MUS;

EID: 81255176515     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2011.06227.x     Document Type: Article

References (49)

1. Chung, U.I. et al 2004. Distinct osteogenic mechanisms of bones of distinct origins. J. Orthop. Sci. 9: 410-414.
2. Chan, D. & O. Jacenko 1998. Phenotypic and biochemical consequences of collagen X mutations in mice and humans. Matrix Biol. 17: 169-184.
3. Aguila, H.L. & D.W. Rowe 2005. Skeletal development, bone remodeling, and hematopoiesis. Immunol. Rev. 208: 7-18.
4. Taichman, R.S., M.J. Reilly & S.G. Emerson 1996. Human osteoblasts support human hematopoietic progenitor cells in vitro bone marrow cultures. Blood 87: 518-524.
5. Zhu, J. et al 2007. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood 109: 3706-3712.
6. Calvi, L.M. et al 2003. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425: 841-846.
7. Visnjic, D. et al 2004. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood 103: 3258-3264.
8. Balduino, A. et al 2005. Bone marrow subendosteal microenvironment harbours functionally distinct haemosupportive stromal cell populations. Cell Tissue Res. 319: 255-266.
9. Adams, G.B. et al 2006. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature 439: 599-603.
10. de Barros, A.P. et al 2010. Osteoblasts and bone marrow mesenchymal stromal cells control hematopoietic stem cell migration and proliferation in 3D in vitro model. PLoS One 5: e9093.
11. Wu, J.Y. et al 2008. Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proc. Natl. Acad. Sci. USA 105: 16976-16981.
12. Wu, J.Y., D.T. Scadden & H.M. Kronenberg 2009. Role of the osteoblast lineage in the bone marrow hematopoietic niches. J. Bone Miner. Res. 24: 759-764.
13. Raaijmakers, M.H. et al 2010. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 464: 852-857.
14. Kiel, M.J. et al 2005. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121: 1109-1121.
15. Mendez-Ferrer, S. et al 2008. Haematopoietic stem cell release is regulated by circadian oscillations. Nature 452: 442-447.
16. Sacchetti, B. et al 2007. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 131: 324-336.
17. Kopp, H.G. et al 2005. The bone marrow vascular niche: home of HSC differentiation and mobilization. Physiology (Bethesda) 20: 349-356.
18. Tokoyoda, K. et al 2004. Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity 20: 707-718.
19. Verfaillie, C.M. 1993. Soluble factor(s) produced by human bone marrow stroma increase cytokine-induced proliferation and maturation of primitive hematopoietic progenitors while preventing their terminal differentiation. Blood 82: 2045-2053.
20. Osmond, D.G. 1990. B cell development in the bone marrow. Semin. Immunol. 2: 173-180.
21. Guba, S.C. et al 1992. Bone marrow stromal fibroblasts secrete interleukin-6 and granulocyte-macrophage colony-stimulating factor in the absence of inflammatory stimulation: demonstration by serum-free bioassay, enzyme-linked immunosorbent assay, and reverse transcriptase polymerase chain reaction. Blood 80: 1190-1198.
22. Avecilla, S.T. et al 2004. Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nat. Med. 10: 64-71.
23. Jung, Y. et al 2006. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone 38: 497-508.
24. Nilsson, S.K. et al 1997. Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model. Blood 89: 4013-4020.
25. Nilsson, S.K., H.M. Johnston & J.A. Coverdale 2001. Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches. Blood 97: 2293-2299.
26. Yoshimoto, M. et al 2003. Direct visualization of transplanted hematopoietic cell reconstitution in intact mouse organs indicates the presence of a niche. Exp. Hematol. 31: 733-740.
27. Zhang, J. et al 2003. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425: 836-841.
28. Xie, Y. et al 2009. Detection of functional haematopoietic stem cell niche using real-time imaging. Nature 457: 97-101.
29. Jacenko, O., P.A. LuValle & B.R. Olsen 1993. Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition. Nature 365: 56-61.
30. Jacenko, O. et al 2002. Linking hematopoiesis to endochondral skeletogenesis through analysis of mice transgenic for collagen X. Am. J. Pathol. 160: 2019-2034.
31. Jacenko, O., S. Ito & B.R. Olsen 1996. Skeletal and hematopoietic defects in mice transgenic for collagen X. Ann. N. Y. Acad. Sci. 785: 278-280.
32. Jacenko, O. et al 2001. A dominant interference collagen X mutation disrupts hypertrophic chondrocyte pericellular matrix and glycosaminoglycan and proteoglycan distribution in transgenic mice. Am. J. Pathol. 159: 2257-2269.
33. Gress, C.J. & O. Jacenko 2000. Growth plate compressions and altered hematopoiesis in collagen X null mice. J. Cell Biol. 149: 983-993.
34. Sweeney, E. et al 2008. Altered endochondral ossification in collagen X mouse models leads to impaired immune responses. Dev. Dyn. 237: 2693-2704.
35. Sweeney, E. et al 2010. Congenic mice confirm that collagen X is required for proper hematopoietic development. PLoS One 5: e9518.
36. Kwan, K.M. et al 1997. Abnormal compartmentalization of cartilage matrix components in mice lacking collagen X: implications for function. J. Cell Biol. 136: 459-471.
37. Rosati, R. et al 1994. Normal long bone growth and development in type X collagen-null mice. Nat. Genet. 8: 129-135.
38. Jacenko, O. et al 1993. A dominant negative mutation in the alpha 1 (X) collagen gene produces spondylometaphyseal defects in mice. Prog. Clin. Biol. Res. 383B: 427-436.
39. Campbell, M.R. et al 2004. Chicken collagen X regulatory sequences restrict transgene expression to hypertrophic cartilage in mice. Am. J. Pathol. 164: 487-499.
40. Schmid, T.M., R.G. Popp & T.F. Linsenmayer 1990. Hypertrophic cartilage matrix. Type X collagen, supramolecular assembly, and calcification. Ann. N. Y. Acad. Sci. 580: 64-73.
41. Verfaillie, C.M. et al 1999. The hematopoietic microenvironment: stromal extracellular matrix components as growth regulators for human hematopoietic progenitors. Hematology 4: 321-333.
42. Borghesi, L.A., Y. Yamashita & P.W. Kincade 1999. Heparan sulfate proteoglycans mediate interleukin-7-dependent B lymphopoiesis. Blood 93: 140-148.
43. Bruno, E. et al 1995. Marrow-derived heparan sulfate proteoglycan mediates the adhesion of hematopoietic progenitor cells to cytokines. Exp. Hematol. 23: 1212-1217.
44. Gupta, P. et al 1998. Structurally specific heparan sulfates support primitive human hematopoiesis by formation of a multimolecular stem cell niche. Blood 92: 4641-4651.
45. Siebertz, B. et al 1999. Expression of glypican-4 in haematopoietic-progenitor and bone-marrow-stromal cells. Biochem. J. 344: 937-943.
46. Nagasawa, T. 2006. Microenvironmental niches in the bone marrow required for B-cell development. Nat. Rev. Immunol. 6: 107-116.
47. Nagasawa, T. et al 1996. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382: 635-638.
48. Kollet, O. et al 2006. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat. Med. 12: 657-664.
49. Lev, R. & S.S. Spicer 1964. Specific staining of sulphate groups with Alcian blue at low Ph. J. Histochem. Cytochem. 12: 309.