Interaction between leptin and leisure-time physical activity and development of hypertension

Blood Pressure

Volumn 20, Issue 6, 2011, Pages 362-369

  Asferg, Camilla ^a   Møgelvang, Rasmus ^b   Flyvbjerg, Allan ^c,d   Frystyk, Jan ^c,d   Jensen, Jan S ^e,f   Marott, Jacob L ^g   Appleyard, Merete ^g   Schnohr, Peter ^g   Jensen, Gorm B ^f,h   Jeppesen, Jørgen ^a,f  

^a GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^b Mental Health Center Glostrup   (Denmark)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d AARHUS UNIVERSITY   (Denmark)

^e GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

^g BISPEBJERG HOSPITAL   (Denmark)

^h HVIDOVRE HOSPITAL   (Denmark)

Author keywords

blood pressure; hypertension; leptin; obesity; overweight; physical activity

Indexed keywords

LEPTIN;

ADULT; ANTIHYPERTENSIVE THERAPY; ARTICLE; DIASTOLIC BLOOD PRESSURE; FEMALE; HUMAN; HYPERTENSION; LEISURE; MALE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; SYSTOLIC BLOOD PRESSURE;

ADIPONECTIN; ADULT; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BODY MASS INDEX; DENMARK; DIASTOLE; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION; IMMUNOASSAY; LEPTIN; LOGISTIC MODELS; MALE; MIDDLE AGED; MOTOR ACTIVITY; ODDS RATIO; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK FACTORS; SYSTOLE;

EID: 81255165789     PISSN: 08037051     EISSN: 16511999     Source Type: Journal    
DOI: 10.3109/00365599.2011.586248     Document Type: Article

References (25)

1. Ezzati M, Lopez AD, Rodgers A, Vander HS, Murray CJ. Selected major risk factors and global and regional burden of disease. Lancet. 2002;360:1347-1360.
2. Rahmouni K, Correia ML, Haynes WG, Mark AL. Obesityassociated hypertension: New insights into mechanisms. Hypertension. 2005;45:9-14.
3. Bogaert YE, Linas S. The role of obesity in the pathogenesis of hypertension. Nat Clin Pract Nephrol. 2009;5:101-111.
4. Mathieu P, Poirier P, Pibarot P, Lemieux I, Despres JP. Visceral obesity: The link among infl ammation, hypertension, and cardiovascular disease. Hypertension. 2009;53:577-584.
5. Redon J, Cifkova R, Laurent S, Nilsson P, Narkiewicz K, Erdine S, et al. Mechanisms of hypertension in the cardiometabolic syndrome. J Hypertens. 2009;27:441-451.
6. Fagard RH. Exercise is good for your blood pressure: Effects of endurance training and resistance training. Clin Exp Pharmacol Physiol. 2006;33:853-856.
7. Fagard RH, Cornelissen VA. Effect of exercise on blood pressure control in hypertensive patients. Eur J Cardiovasc Prev Rehabil. 2007;14:12-17.
8. Hu G, Barengo NC, Tuomilehto J, Lakka TA, Nissinen A, Jousilahti P. Relationship of physical activity and body mass index to the risk of hypertension: A prospective study in Finland. Hypertension. 2004;43:25-30.
9. Martin SS, Qasim A, Reilly MP. Leptin resistance: A possible interface of infl ammation and metabolism in obesity-related cardiovascular disease. J Am Coll Cardiol. 2008;52:1201-1210.
10. Galletti F, D 'E lia L, Barba G, Siani A, Cappuccio FP, Farinaro E, et al. High-circulating leptin levels are associated with greater risk of hypertension in men independently of body mass and insulin resistance: Results of an eight-year follow-up study. J Clin Endocrinol Metab. 2008;93:3922-3926.
11. Asferg C, Mogelvang R, Flyvbjerg A, Frystyk J, Jensen JS, Marott JL, et a. Leptin, Not Adiponectin, Predicts Hypertension in the Copenhagen City Heart Study. Am J Hypertens. 2010;23:327-333.
12. Appelyard M, Jensen G, Scharling H, Schnohr P. The Copenhagen City Heart Study. Osterbroundersogelsen. A book of tables with data from the fi rst examination (1976 - 78) and a fi ve year follow-up (1981 - 83). The Copenhagen City Heart Study Group. Scand J Soc Med Suppl. 1989;41:1-160.
13. Schnohr P, Jensen G, Lange P, Scharling H, Appelyard M. The Copenhagen City Heart Study. ø sterbrounders ø gelsen. Tables with data from the third examination. European Heart Journal Supplement H. 2002;3:H1-H83.
14. Saltin B, Grimby G. Physiological analysis of middle-aged and old former athletes. Comparison with still active athletes of the same ages. Circulation. 1968;38:1104-1115.
15. Schnohr P, Lange P, Scharling H, Jensen JS. Long-term physical activity in leisure time and mortality from coronary heart disease, stroke, respiratory diseases, and cancer. The Copenhagen City Heart Study. Eur J Cardiovasc Prev Rehabil. 2006;13:173-179.
16. Yildiz BO, Suchard MA, Wong ML, McCann SM, Licinio J. Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proc Natl Acad Sci USA. 2004;101:10434-10439.
17. Frystyk J, Tarnow L, Hansen TK, Parving HH, Flyvbjerg A. Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications. Diabetologia. 2005;48: 1911-1918.
18. Parikh NI, Pencina MJ, Wang TJ, Benjamin EJ, Lanier KJ, Levy D, et al. A risk score for predicting near-term incidence of hypertension: The Framingham Heart Study. Ann Intern Med. 2008;148:102-110.
19. Jeppesen J. Triglycerides, high-density lipoprotein cholesterol, and risk of ischemic heart disease: A view from the Copenhagen Male Study. Metab Syndr Relat Disord. 2003;1: 33-53.
20. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes. 1988;37:1595-1607.
21. Savoia C, Schiffrin EL. Infl ammation in hypertension. Curr Opin Nephrol Hypertens. 2006;15:152-158.
22. Sabatier MJ, McCully KK, Marinik EL, Schwark EH, Haddow S, Cortez-Cooper M, et al. Leptin, blood pressure, and aerobic capacity in women. Am J Hypertens. 2008;21: 1245-1250.
23. Kimura M, Tateishi N, Shiota T, Yoshie F, Yamauchi H, Suzuki M, et al. Long-term exercise down-regulates leptin receptor mRNA in the arcuate nucleus. Neuroreport. 2004;15: 713-716.
24. Schnohr P, Jensen JS, Scharling H, Nordestgaard BG. Coronary heart disease risk factors ranked by importance for the individual and community. A 21 year follow-up of 12 000 men and women from The Copenhagen City Heart Study. Eur Heart J. 2002;23:620-626.
25. Azevedo A, Barros H. C-reactive protein is an intermediate step between obesity and hypertension. Arch Intern Med. 2006;166:1526-1527.