Mechanosensing can result from adhesion molecule dynamics

Biophysical Journal

Volumn 101, Issue 10, 2011, Pages

  Krzyszczyk, Paulina ^a   Wolgemuth, Charles W ^b  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN;

ARTICLE; BIOLOGICAL MODEL; CELL ADHESION; CELL MOTION; CELLS; CYTOLOGY; MECHANOTRANSDUCTION; METABOLISM; POLYMERIZATION; PSEUDOPODIUM;

ACTINS; CELL ADHESION; CELL MOVEMENT; CELLS; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; POLYMERIZATION; PSEUDOPODIA;

EID: 81255164846     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2011.10.003     Document Type: Article

References (12)

1. D.E. Discher, P. Janmey, and Y.-L. Wang Tissue cells feel and respond to the stiffness of their substrate Science 310 2005 1139 1143
2. I.B. Bischofs, and U.S. Schwarz Cell organization in soft media due to active mechanosensing Proc. Natl. Acad. Sci. USA 100 2003 9274 9279
3. A.J. Engler, and C. Carag-Krieger D.E. Discher Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating J. Cell Sci. 121 2008 3794 3802
4. A. Engler, and L. Bacakova D. Discher Substrate compliance versus ligand density in cell on gel responses Biophys. J. 86 2004 617 628
5. C.-M. Lo, and H.B. Wang Y.L. Wang Cell movement is guided by the rigidity of the substrate Biophys. J. 79 2000 144 152
6. C.K. Choi, and M. Vicente-Manzanares A.R. Horwitz Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner Nat. Cell Biol. 10 2008 1039 1050
7. C. Cluzel, and F. Saltel B. Wehrle-Haller The mechanisms and dynamics of αvβ3 integrin clustering in living cells J. Cell Biol. 171 2005 383 392
8. S. Walcott, and S.X. Sun A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells Proc. Natl. Acad. Sci. USA 107 2010 7757 7762
9. 1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy Mol. Biol. Cell 18 2007 1634 1644
10. B. Wehrle-Haller, and B.A. Imhof The inner lives of focal adhesions Trends Cell Biol. 12 2002 382 389
11. M. Dembo, and Y.-L. Wang Stresses at the cell-to-substrate interface during locomotion of fibroblasts Biophys. J. 76 1999 2307 2316
12. B. Harland, S. Walcott, and S.X. Sun Adhesion dynamics and durotaxis in migrating cells Phys. Biol. 8 2011 015011