Tetrodotoxin- and resiniferatoxin-induced changes in paracervical ganglion ChAT- and nNOS-IR neurons supplying the urinary bladder in female pigs

Acta Veterinaria Hungarica

Volumn 59, Issue 4, 2011, Pages 455-463

  Burliński, Piotr ^a   Gonkowski, Sławomir ^a   Całka, Jarosław ^a  

^a UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

Author keywords

ChAT; NNOS; Paracervical ganglion; Pig; RTX; TTX

Indexed keywords

CHOLINE ACETYLTRANSFERASE; DITERPENE; NEURONAL NITRIC OXIDE SYNTHASE; RESINIFERATOXIN; TETRODOTOXIN;

ANIMAL; ARTICLE; AUTONOMIC GANGLION; BLADDER; DRUG EFFECT; FEMALE; INNERVATION; METABOLISM; NERVE CELL; PHYSIOLOGY; PROTEIN TRANSPORT; SWINE;

ANIMALS; CHOLINE O-ACETYLTRANSFERASE; DITERPENES; FEMALE; GANGLIA, AUTONOMIC; NEURONS; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN TRANSPORT; SWINE; TETRODOTOXIN; URINARY BLADDER;

SUIDAE; SUS;

EID: 81255163118     PISSN: 02366290     EISSN: 15882705     Source Type: Journal    
DOI: 10.1556/AVet.2011.033     Document Type: Article

References (41)

1. Apostolidis, A., Brady, C. M., Yiangou, Y., Davis, J., Fowler, C. J. and Anand, P. (2005): Capsaicin receptor TRPV1 in urothelium of neurogenic human bladders and effect of intravesical resiniferatoxin. Urology 65, 400-405. (Pubitemid 40248050)
2. Apostolidis, A., Gonzales, G. E. and Fowler, C. J. (2006): Effect of intravesical resiniferatoxin (RTX) on lower urinary tract symptoms, urodynamic parameters, and quality of life of patients with urodynamic increased bladder sensation. Eur. Urol. 50, 1299-1305. (Pubitemid 44692915)
3. Barber, R. P., Phelps, P. E., Houser, C. R., Crawford, G. D., Salvaterra, P. M. and Vaughn, J. E. (1984): The morphology and distribution of neurons containing choline acetyltransferase in the adult rat spinal cord: an immunohistochemical study. J. Comp. Neurol. 229, 329-335.
4. Bossowska, A., Borkowski, A., Radziszewski, P. and Majewski, M. (2008): Resiniferatoxin (RTX)- and tetrodotoxin (TTX)-induced changes in chemical coding of sensory neurons in lumbar and sacral/coccygeal dorsal root ganglia (DRG) supplying porcine urinary bladder. Urologia Pol. 61,Suppl. 1, 92.
5. Brady, C. M., Apostolidis, A., Yiangou, Y., Baecker, P. A., Ford, A. P., Freeman, A., Jacques, T. S., Fowler, C. J. and Anand, P. (2004): P2X3-immunoreactive nerve fibres in neurogenic detrusor overactivity and the effect of intravesical resiniferatoxin. Eur. Urol. 46, 247-253. (Pubitemid 38902749)
6. Całka, J., Załcki, M. and Arciszewski, B. (2008): Co-localisation of NOS- and ChAT-immunoreactivity in the spinal autonomic nuclei of the pig. An immunocytochemical study. Bull. Vet. Inst. Puławy 52, 635-641.
7. Chancellor, M. B. and de Groat, W. C. (1999): Intravesical capsaicin and resiniferatoxin therapy: spicing up the ways to treat the overactive bladder. J. Urol. 162, 3-11. (Pubitemid 29420868)
8. Che, Y. H., Tamatani, M. and Tohyama, M. (2000): Changes in mRNA for post-synaptic density-95 (PSD-95) and carboxy-terminal PDZ ligand of neuronal nitric oxide synthase following facial nerve transection. Mol. Brain Res. 76, 325-335. (Pubitemid 30179769)
9. Crowe, R. and Burnstock, G. (1989): A histochemical and immunohistochemical study of the autonomic innervation of the lower urinary tract of the female pig. Is the pig a good model for the human bladder and urethra? J. Urol. 141, 414-422. (Pubitemid 19061335)
10. de Groat, W. C. and Ryall, R. W. (1969): Reflexes to sacral parasympathetic neurones concerned with micturition in the cat. J. Physiol. 200, 87-108.
11. Dokita, S., Morgan, W. R., Wheeler, M. A., Yoshida, M. and Latifpour, J. (1991): NG-nitro-Larginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle. Life Sci. 48, 2429-2436.
12. Ehren, I., Iversen, H., Jansson, O., Adolfsson, J. and Wiklund, N. P. (1994): Localisation of nitric oxide synthase activity in the human lower urinary tract and its correlation with neuroeffector responses. Urology 44, 683-687.
13. Gibbins, I. L. (1995): Chemical neuroanatomy of sympathetic ganglia. In: McLachlan, E. M. (ed.) Autonomic Ganglia. Harwood Academic Publishers, Luxembourg. pp. 73-121.
14. Hann-Chorng, K. (2008): Novel treatment of overactive bladder and detrusor overactivity with intravesical resiniferatoxin. Incont. Pelvic Floor Dysfunct. 2, 17-20.
15. Keast, J. R. (1995a): Visualization and immunohistochemical characterization of sympathetic and parasympathetic neurons in the male rat major pelvic ganglion. Neuroscience 66, 655-662.
16. Keast, J. R. (1995b): Pelvic ganglia. In: McLachlan, E. M. (ed.) Autonomic Ganglia. Harwood Academic Publishers, Luxembourg. pp. 445-479.
17. Keast, J. R. (1999): Unusual autonomic ganglia: connections, chemistry, and plasticity of pelvic ganglia. Int. Rev. Cytol. 193, 1-69. (Pubitemid 29423642)
18. Keast, J. R., Luckensmeyer, G. B. and Schemann, M. (1995): All pelvic neurons in male rats contain immunoreactivity for the synthetic enzymes of either noradrenaline or acetylcholine. Neurosci. Lett. 196, 209-212.
19. Lazzeri, M., Spinelli, M., Beneforti, P., Malaguti, S., Giardiello, G. and Turini, D. (2004): Intravesical infusion of resiniferatoxin by temporary in situ drug delivery system to treat interstitial cystitis: a pilot study. Eur. Urol. 45, 98-102. (Pubitemid 37549002)
20. Marcil, J., Walczak, J.-S., Guindon, J., Ngoc, A. H., Lu, S. and Beaulieu, P. (2006): Antinociceptive effects of tetrodotoxin (TTX) in rodents. Br. J. Anaesth. 96, 761-768. (Pubitemid 43786693)
21. Mitchell, B. S. (1993): Morphology and neurochemistry of the pelvic, and paracervical ganglia. Histol. Histopathol. 8, 761-773. (Pubitemid 23351638)
22. Mitchell, B. S., Ahmed, E. and Stauber, V. V. (1993): Projections of the guinea-pig paracervical ganglion to pelvic viscera. Histochem. J. 25, 51-56. (Pubitemid 23071787)
23. Nikonenko, I., Jourdain, P. and Muller, D. (2003): Presynaptic remodeling contributes to activitydependent synaptogenesis. J. Neurosci. 23, 8498-8505. (Pubitemid 37158749)
24. Nikonenko, I., Boda, B., Steen, S., Knott, G., Welker, E. and Muller, D. (2008): PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling. J. Cell. Biol. 183, 1115-1127.
25. Palma, P. C. R., Thiel, M., Riccetto, C. L. Z., Dambros, M., Miyaoka, R. and Netto, N. R. (2004): Resiniferatoxin for detrusor instability refractory to anticholinergics. Urol. Neurol. 30, 53-58. (Pubitemid 38401315)
26. Papka, R. E., Traurig, H. H. and Klenn, P. (1987): Paracervical ganglia of the female rat: histochemistry and immunohistochemistry of neurons, SIF cells, and nerve terminals. Am. J. Anat. 179, 243-257. (Pubitemid 17106914)
27. Persson, K. and Andersson, K-E. (1992): Nitric oxide and relaxation of the lower urinary tract. Br. J. Pharmacol. 106, 416-422.
28. Persson, K., Alm, P., Johansson, K., Larsson, B. and Andersson, K-E. (1993): Nitric oxide synthase in pig lower urinary tract: immunohistochemistry, NADPH diaphorase histochemistry and functional effects. Br. J. Pharmacol. 110, 521-530. (Pubitemid 23279255)
29. Pidsudko, Z., Kaleczyc, J., Majewski, M., Łakomy, M., Scheuermann, D. W. and Timmermans, J. P. (2001): Differences in the distribution and chemical coding between neurons in the inferior mesenteric ganglion supplying the colon and rectum in the pig. Cell Tissue Res. 303, 147-158. (Pubitemid 32186595)
30. Podlasz, P. and Wa̧sowicz, K. (2008): Neurochemical characteristics of paracervical ganglion in the pig. Veterinarni Medicina 53, 135-146. (Pubitemid 351468631)
31. Radziszewski, P. and Borkowski, A. (2001): Intravesical resiniferatoxin for the treatment of overactive bladder, painful bladder and interstitial cystitis. Int. Urogyn. 12,Suppl. 3, 64.
32. Sánchez-Islas, E. and León-Olea, M. (2004): Nitric oxide synthase inhibition during synaptic maturation decreases synapsin I immunoreactivity in rat brain. Nitric Oxide 10, 141-149. (Pubitemid 38668663)
33. Shi, J, Liu, T. T., Wang, X., Epstein, D. H., Zhao, L. Y., Zhang, X. L. and Lu, L. (2009): Tetrodotoxin reduces cue-induced drug craving and anxiety in abstinent heroin addicts. Pharmacol. Biochem. Behav. 92, 603-607.
34. Sunico, C. R., Portillo, F., González-Forero, D. and Moreno-López, B. (2005): Nitric-oxidedirected synaptic remodeling in the adult mammal CNS. J. Neurosci. 25, 1448-1458. (Pubitemid 40250721)
35. Swindle, M. M. (1992): Swine as Models in Biomedical Research. Iowa State University Press, Ames, Iowa.
36. Vaughan, C. W. and Satchell, P. M. (1995): Urine storage mechanisms. Prog. Neurobiol. 46, 215-237.
37. Verma, N., Rettenmeier, A. W. and Schmitz-Spanke, S. (2011): Recent advances in the use of Sus scrofa (pig) as a model system for proteomic studies. Proteomics 11, 776-793.
38. Vizzard, M. A., Erdman, S. L., Förstermann, U. and de Groat, W. C. (1994): Differential distribution of nitric oxide synthase in neural pathways to the urogenital organs (urethra, penis, urinary bladder) of the rat. Brain Res. 646, 279-291. (Pubitemid 24151764)
39. Wojtkiewicz, J., Bossowska, A., Zapart, A., Skobowiat, C., Borkowski, A., Radziszewski, P. and Majewski, M. (2008): Tetrodotoxin-induced changes in the chemical coding of inferior mesenteric ganglion (IMG) neurons supplying porcine urinary bladder. Urologia Pol. 61,Suppl. 1, 57-58.
40. Yoshimura, N., Bennett, N. E., Hayashi, Y., Ogawa, T., Nishizawa, O., Chancellor, M. B., de Groat, W. C. and Seki, S. (2006): Bladder overactivity and hyperexcitability of bladder afferent neurons after intrathecal delivery of nerve growth factor in rats. J. Neurosc. 26, 10847-10855.
41. Zhou, Y. and Ling, E-A. (1999): Neuronal nitric oxide synthase in the neural pathways of the urinary bladder. J. Anat. 194, 481-496. (Pubitemid 29335618)