A review of the health consequences of the vitamin D deficiency pandemic

Journal of the Neurological Sciences

Volumn 311, Issue 1-2, 2011, Pages 15-18

  Dobnig, Harald ^a,b  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b Diagnostikinstitut Univ Prof Dr H Dobnig GmbH   (Austria)

Author keywords

25 hydroxyvitamin D; Cancer; Extraskeletal effects; Infections; Mortality

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL; ERGOCALCIFEROL; PARATHYROID HORMONE; PHOSPHORUS; POLYPEPTIDE ANTIBIOTIC AGENT; VITAMIN D;

ASTHMA; BONE DENSITY; BONE TURNOVER; BREAST CANCER; CANCER RISK; CHRONIC OBSTRUCTIVE LUNG DISEASE; COLON CANCER; DISEASE ASSOCIATION; EPITHELIUM CELL; FEMUR; FRACTURE; HEART INFARCTION; HIP FRACTURE; HUMAN; HYPERTENSION; INTESTINE ABSORPTION; LOW DRUG DOSE; MACROPHAGE; METAPHYSIS; MONOCYTE; MUSCLE FUNCTION; OSTEOCLAST; OSTEOMALACIA; OSTEOPOROSIS; PANCREAS CANCER; PARATHYROID HORMONE RELEASE; PATIENT COMPLIANCE; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW; RICKETS; STROKE; SUN EXPOSURE; ULTRAVIOLET RADIATION; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; WINTER;

EID: 81255149585     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2011.08.046     Document Type: Article

References (23)

1. G. Jones, and D.E. Prosser The activating enzymes of vitamin D metabolism (25- and 1 α-hydroxylases) D. Feldman, J.W. Pike, J.S. Adams, Vitamin D 3rd edition 2011 Academic Press New York 23 42
2. J. Chan, K. Jaceldo-Siegl, and G.E. Fraser Determinants of serum 25 hydroxyvitamin D levels in a nationwide cohort of blacks and non-Hispanic whites Cancer Causes Control 21 2010 501 511
3. A.C. Ross, J.E. Manson, S.A. Abrams, J.F. Aloia, P.M. Brannon, and S.K. Clinton The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know J Clin Endocrinol Metab 96 2011 53 58
4. J. Allgrove A practical approach to rickets Endocr Dev 16 2009 115 132
5. S. Boonen, H.A. Bischoff-Ferrari, C. Cooper, P. Lips, O. Ljunggren, and P.J. Meunier Addressing the musculoskeletal components of fracture risk with calcium and vitamin D: a review of the evidence Calcif Tissue Int 78 2006 257 270
6. P. Mahon, N. Harvey, S. Crozier, H. Inskip, S. Robinson, and N. Arden Low maternal vitamin D status and fetal bone development: cohort study J Bone Miner Res 25 2010 14 19
7. H.A. Bischoff-Ferrari, D.P. Kiel, B. Dawson-Hughes, J.E. Orav, R. Li, and D. Spiegelman Dietary calcium and serum 25-hydroxyvitamin D status in relation to bone mineral density among U.S. adults J Bone Miner Res 24 2009 935 942
8. M.C. Chapuy, M.E. Arlot, F. Duboeuf, J. Brun, B. Crouzet, and S. Arnaud Vitamin D3 and calcium to prevent hip fractures in the elderly women N Engl Med 327 1992 1637 1642
9. H.A. Bischoff-Ferrari, W.C. Willett, J.B. Wong, A.E. Stuck, H.B. Staehelin, and E.J. Orav Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials Arch Intern Med 169 2009 551 561
10. N.O. Kuchuk, S.M. Pluijm, N.M. van Schoor, C.W. Looman, J.H. Smit, and P. Lips Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons J Clin Endocrinol Metab 94 2009 1244 1250
11. H.A. Bischoff-Ferrari, T. Dietrich, E.J. Orav, F.B. Hu, Y. Zhang, and E.W. Karlson Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or = 60 y Am J Clin Nutr 80 2004 752 758 (Pubitemid 41115542)
12. M. Pfeifer, B. Begerow, H.W. Minne, K. Suppan, A. Fahrleitner-Pammer, and H. Dobnig Effects of a long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community-dwelling older individuals Osteoporos Int 20 2009 315 322
13. M.F. Holick, N.C. Binkley, H.A. Bischoff-Ferrari, C.M. Gordon, D.A. Hanley, and R.P. Heaney Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline J Clin Endocrinol Metab 96 2011 1911 1930
14. J.H. White Vitamin D as an inducer of cathelicidin antimicrobial peptide expression: past, present and future J Steroid Biochem Mol Biol 121 2010 234 238
15. A.A. Ginde, J.M. Mansbach, and C.A. Camargo Jr. Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey Arch Intern Med 169 2009 384 390
16. M.L. Melamed, E.D. Michos, W. Post, and B. Astor 25-Hydroxyvitamin D levels and the risk of mortality in the general population Arch Intern Med 168 2008 1629 1637
17. H. Dobnig, S. Pilz, H. Scharnagl, W. Renner, U. Seelhorst, and B. Wellnitz Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality Arch Intern Med 168 2008 1340 1349 (Pubitemid 351930842)
18. S. Pilz, H. Dobnig, J.E. Fischer, B. Wellnitz, U. Seelhorst, and B.O. Boehm Low vitamin d levels predict stroke in patients referred to coronary angiography Stroke 39 2008 2611 2613
19. E. Giovannucci, Y. Liu, B.W. Hollis, and E.B. Rimm 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study Arch Intern Med 168 2008 1174 1180 (Pubitemid 351831400)
20. S.E. Judd, M.S. Nanes, T.R. Ziegler, P.W. Wilson, and V. Tangpricha Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination Survey Am J Clin Nutr 87 2008 136 141
21. K.K. Deeb, D.L. Trump, and C.S. Johnson Vitamin D signalling pathways in cancer: potential for anticancer therapeutics Nat Rev Cancer 7 2007 684 700 (Pubitemid 47327412)
22. S. Pilz, A. Tomaschitz, B. Obermayer-Pietsch, H. Dobnig, and T.R. Pieber Epidemiology of vitamin D insufficiency and cancer mortality Anticancer Res 29 2009 3699 3704
23. J.M. Lappe, D. Travers-Gustafson, K.M. Davies, R.R. Recker, and R.P. Heaney Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial Am J Clin Nutr 85 2007 1586 1591 (Pubitemid 46890428)