Polyamidoamine-grafted multiwalled carbon nanotubes for gene delivery: Synthesis, transfection and intracellular trafficking

Bioconjugate Chemistry

Volumn 22, Issue 11, 2011, Pages 2237-2243

  Liu, Min ^a   Chen, Biao ^a   Xue, Yanan ^b   Huang, Jie ^a   Zhang, Liming ^a   Huang, Shiwen ^b   Li, Qingwen ^a   Zhang, Zhijun ^a  

^a SUZHOU INSTITUTE OF NANO TECH AND NANO BIONICS   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EFFICIENCY; GENE EXPRESSION; MULTIWALLED CARBON NANOTUBES (MWCN); SOLUTIONS; YARN;

AMIDE FORMATION; FUNCTIONALIZED MULTI-WALLED CARBON NANOTUBES; GENE DELIVERY; GENE DELIVERY SYSTEMS; INTRACELLULAR TRAFFICKING; LOCALISED; MULTI-WALLED-CARBON-NANOTUBES; NOVEL GENES; POLYAMIDOAMINES; TRANSFECTION EFFICIENCY;

GENE TRANSFER;

AMIDE; DNA; MULTI WALLED NANOTUBE; POLYAMIDOAMINE;

AQUEOUS SOLUTION; ARTICLE; CELL MIGRATION; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; CYTOTOXICITY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE SYNTHESIS; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; IN VITRO STUDY;

PAA;

EID: 81255138081     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200189f     Document Type: Article

References (30)

1. Anderson, W. F. (1998) Human gene therapy Nature 392, 25-30 (Pubitemid 28215190)
2. Li, S. and Huang, L. (2000) Nonviral gene therapy: promises and challenges Gene Ther. 7, 31-34 (Pubitemid 30077146)
3. Wong, S. Y., Pelet, J. M., and Putnam, D. (2007) Polymer systems for gene delivery-past, present, and future Prog. Polym. Sci. 32, 799-837 (Pubitemid 47198291)
4. Mintzer, M. A. and Simanek, E. E. (2009) Nonviral vectors for gene delivery Chem. Rev. 109, 259-302
5. Richard, C., Mignet, N., Largeau, C., Escriou, V., Bessodes, M., and Scherman, D. (2009) Functionalization of single- and multi-walled carbon nanotubes with cationic amphiphiles for plasmid DNA complexation and transfection Nano Res. 2, 638-647
6. Liu, Y., Wu, D. C., Zhang, W. D., Jiang, X., He, C. B., Chung, T. S., Goh, S. H., and Leong, K. W. (2005) Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA Angew. Chem., Int. Ed. 44, 4782-4785 (Pubitemid 41059186)
7. Pantarotto, D., Singh, R., McCarthy, D., Erhardt, M., Briand, J. P., Prato, M., Kostarelos, K., and Bianco, A. (2004) Functionalized carbon nanotubes for plasmid DNA gene delivery Angew. Chem., Int. Ed. 43, 5242-5246 (Pubitemid 39382552)
8. Herrero, M. A., Toma, F. M., Al-Jamal, K. T., Kostarelos, K., Bianco, A., Ros, T. D., Bano, F., Casalis, L., Scoles, G., and Prato, M. (2009) Synthesis and characterization of a carbon nanotube-dendron series for efficient siRNA delivery J. Am. Chem. Soc. 131, 9843-9848
9. Feng, L. Z., Zhang, S., and Liu, Z. (2011) Graphene based gene transfection Nanoscale 3, 1252-1257
10. Zhang, L. M., Lu, Z. X., Zhao, Q. H., Huang, J., Shen, H., and Zhang, Z. J. (2011) Enhanced chemotherapy efficacy by sequential delivery of siRNA and anticancer drugs using PEI-grafted graphene oxide Small 7, 460-464
11. Liu, Z., Winters, M., Holodniy, M., and Dai, H. J. (2007) siRNA delivery into human T cells and primary cells with carbon-nanotube transporters Angew. Chem., Int. Ed. 46, 2023-2027 (Pubitemid 46973660)
12. Bartholomeusz, G., Cherukuri, P., Kingston, J., Cognet, L., Lemos, R., Leeuw, T. K., Gumbiner-Russo, L., Weisman, R. B., and Powis, G. (2009) In vivo therapeutic silencing of hypoxia-inducible factor 1 alpha (HIF-1α) using single-walled carbon nanotubes noncovalently coated with siRNA Nano Res. 2, 279-291
13. Shi, X. Y., Wang, S. H., Shen, M. W., Antwerp, M. E., Chen, X. S., Li, C., Petersen, E. J., Huang, Q. G., Weber, W. J., and Baker, J. R. (2009) Multifunctional dendrimer-modified multiwalled carbon nanotubes: synthesis, characterization, and in vitro cancer cell targeting and imaging Biomacromolecules 10, 1744-1750
14. Pan, B. F., Cui, D. X., Xu, P., Ozkan, C., Feng, G., Ozkan, M., Huang, T., Chu, B. F., Li, Q., He, R., and Hu, G. H. (2009) Synthesis and characterization of polyamidoamine dendrimer-coated multi-walled carbon nanotubes and their application in gene delivery systems Nanotechnology 20, 125101
15. McCarroll, J., Baigude, H., Yang, C. S., and Rana, T. M. (2010) Nanotubes functionalized with lipids and natural amino acid dendrimers: a new strategy to create nanomaterials for delivering systemic RNAi Bioconjugate Chem. 21, 56-63
16. Qin, W. L., Yang, K. Q., Tang, H., Tan, L., Xie, Q. J., Ma, M., Zhang, Y. Y., and Yao, S. Z. (2011) Improved GFP gene transfection mediated by polyamidoamine dendrimer-functionalized multi-walled carbon nanotubes with high biocompatibility Colloids Surf., B: Biointerfaces 84, 206-213
17. Zhang, B. L., Chen, Q., Tang, H., Xie, Q. J., Ma, M., Tan, L., Zhang, Y. Y., and Yao, S. Z. (2011) Characterization of and biomolecule immobilization on the biocompatible multi-walled carbon nanotubes generated by functionalization with polyamidoamine dendrimers Colloids Surf., B: Biointerfaces 80, 18-25
18. Dufes, C., Uchegbu, I. F., and Schatzlein, A. G. (2005) Dendrimers in gene delivery Adv. Drug Delivery Rev. 57, 2177
19. Danusso, F. and Ferruti, P. (1970) Synthesis of tertiary amine polymers Polymer 11, 88-113
20. Lin, C., Blaauboer, C. J., Timoneda, M. M., Lok, M. C., Steenbergen, M. V., Hennink, W. E., Zhong, Z. Y., Feijen, J., and Engbersen, J. F. J. (2008) Bioreducible poly(amido amine)s with oligoamine side chains: Synthesis, characterization, and structural effects on gene delivery J. Controlled Release 126, 166-174
21. Reschel, T., Konak, C., Oupicky, D., Seymour, L. W., and Ulbrich, K. (2002) Physical properties and in vitro transfection efficiency of gene delivery vectors based on complexes of DNA with synthetic polycations J. Controlled Release 81, 201-217 (Pubitemid 34454861)
22. Liu, M., Chen, J., Cheng, Y. P., Xue, Y. N., Zhuo, R. X., and Huang, S. W. (2010) Novel poly(amidoamine)s with pendant primary amines as highly efficient gene delivery vectors Macromol. Biosci. 10, 384-392
23. Liu, J., Rinzler, A. G., Dai, H. J., Hafner, J. H., Bradley, R. K., Boul, P. J., Lu, A., Iverson, T., Shelimov, K., Huffman, C. B., Rodriguez-Macias, F., Shon, Y. S., Lee, T. R., Colbert, D. T., and Smalley, R. E. (1998) Fullerene pipes Science 280, 1253-1255
24. Ahmed, M., Jiang, X. Z., Deng, Z. C., and Narain, R. (2009) Cationic glycol-functionalized single-walled carbon nanotubes as efficient gene delivery vehicles Bioconjugate Chem. 20, 2017-2022
25. Kunath, K., Harpe, A. V., Fischer, D., Petersen, H., Bickel, U., Voigt, K., and Thomas, K. (2003) Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine J. Controlled Release 89, 113-125 (Pubitemid 36412116)
26. Choksakulnimitr, S., Masuda, S., Tokuda, H., Takakura, Y., and Hashida, M. (1995) In vitro cytotoxicity of macromolecules in different cell culture systems J. Controlled Release 34, 233-241
27. Lacerda, L., Ali-Boucetta, H., Herrero, M. A., Pastorin, G., Bianco, L., Prato, M., and Kostarelos, K. (2008) Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes Nanomedicine 3, 149-161 (Pubitemid 351611853)
28. Dumortier, H., Lacotte, S., Pastorin, G., Marega, R., Wu, W., Bonifazi, D., Briand, J. P., Prato, M., Muller, S., and Bianco, A. (2006) Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells Nano Lett. 6, 1522-1528 (Pubitemid 44195341)
29. Singh, R., Pantarotto, D., Lacerda, L., Pastorin, G., Klumpp, C., Prato, M., Bianco, A., and Kostarelos, K. (2006) Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers Proc. Natl. Acad. Sci. 103, 3357-3362 (Pubitemid 43346474)
30. Gao, L. Z., Nie, L., Wang, T. H., Qin, Y. J., Guo, Z. X., Yang, D. L., and Yan, X. Y. (2006) Carbon nanotube delivery of the GFP gene into mammalian cells ChemBioChem 7, 239-242 (Pubitemid 43220934)