Systemic delivery of BH4 anti-apoptotic peptide using CPPs prevents cardiac ischemia-reperfusion injuries in vivo

Journal of Controlled Release

Volumn 156, Issue 2, 2011, Pages 146-153

  Boisguerin, Prisca ^a,c   Redt Clouet, Christelle ^b   Franck Miclo, Alicia ^b   Licheheb, Sana ^a   Nargeot, Joël ^b   Barrère Lemaire, Stéphanie ^b   Lebleu, Bernard ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIV MONTPELLIER   (France)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Anti apoptotic peptide; Cardioprotection; Cell penetrating peptides; In vivo; Ischemia reperfusion; Systemic delivery

Indexed keywords

CARDIOPROTECTION; CELL-PENETRATING PEPTIDE; IN VIVO; ISCHEMIA/REPERFUSION; SYSTEMIC DELIVERY;

CELL DEATH; MAMMALS; OLIGONUCLEOTIDES;

PEPTIDES;

BCL 2 HOMOLOGY DOMAIN 4; CELL PENETRATING PEPTIDE; OLIGONUCLEOTIDE; PEPTIDES AND PROTEINS; PROTEIN BCL XL; PROTEIN PIP2B; STAUROSPORINE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ENDOSOME; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REPERFUSION INJURY;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BCL-X PROTEIN; CELL LINE; CELL-PENETRATING PEPTIDES; CELLS, CULTURED; HEART; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; PEPTIDES;

EID: 81255135930     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.07.037     Document Type: Article

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