Elasticity and viscoelasticity of embolization microspheres

Journal of the Mechanical Behavior of Biomedical Materials

Volumn 4, Issue 8, 2011, Pages 2161-2167

  Hidaka, Kuniyuki ^a,b   Moine, Laurence ^c   Collin, Guillaume ^d   Labarre, Denis ^c   Louis Grossiord, Jean ^c   Huang, Nicolas ^c   Osuga, Keigo ^e   Wada, Shigeo ^b   Laurent, Alexandre ^f  

^a OSAKA UNIVERSITY HOSPITAL   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE   (France)

^e OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Compression test; Embolization microsphere; Relaxation half time; Relaxation test; Vascular interventional radiology; Young's modulus

Indexed keywords

COMPRESSION TESTS; EMBOLIZATION; INTERVENTIONAL RADIOLOGY; RELAXATION HALF TIME; RELAXATION TEST; YOUNG'S MODULUS;

COMPRESSION TESTING; ELASTIC MODULI; MICROSPHERES; MONOLAYERS; RADIOLOGY; RIGIDITY;

ELASTICITY;

ACRYLAMIDO POLYVINYL ALCOHOL MICROSPHERE; GELATIN; MICROSPHERE; POLY(METHYL METHACRYLATE); POLYPHOSPHAZENE COATED POLYMETHYLMETHACRYLATE MICROSPHERE; POLYVINYL ALCOHOL; TRIS ACRYL GELATIN MICROSPHERE; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL EMBOLISM; ELASTICITY; PRIORITY JOURNAL; VISCOELASTICITY; YOUNG MODULUS;

ARTERIES; BIOCOMPATIBLE MATERIALS; ELASTIC MODULUS; EMBOLIZATION, THERAPEUTIC; GELATIN; MICROSPHERES; POLYMETHYL METHACRYLATE; POLYVINYL ALCOHOL; STRESS, MECHANICAL; VISCOSITY;

EID: 81255127269     PISSN: 17516161     EISSN: 18780180     Source Type: Journal    
DOI: 10.1016/j.jmbbm.2011.08.001     Document Type: Article

References (40)

1. Andrei D.C., Briscoe B.J., Luckham P.F., Williams D.R. The deformation of microscopic gel particles. J. Chim. Phys. 1996, 93:960-976.
2. Andrews R.T., Binkert C.A. Relative rates of blood flow reduction during transcatheter arterial embolization with tris-acryl gelatin microspheres or polyvinyl alcohol: quantitative comparison in a swine model. J. Vasc. Interv. Radiol. 2003, 14:1311-1316.
3. Barr J.D., Lemley T.J., Petrochko C.N. Polyvinyl alcohol foam particle sizes and concentrations injectable through microcatheters. J. Vasc. Interv. Radiol. 1998, 9:113-118.
4. Bendszus M., Klein R., Burger R., Warmuth-Metz M., Hofmann E., Solymosi L. Efficacy of trisacryl gelatin microspheres versus polyvinyl alcohol particles in the preoperative embolization of meningiomas. Am. J. Neuroradiol. 2000, 21:255-261.
5. Bonomo G., Pedicini V., Monfardini L., Della Vigna P., Poretti D., Orgera G., Orsi F. Bland embolization in patients with unresectable hepatocellular carcinoma using precise, tightly size-calibrated, anti-inflammatory microparticles: first clinical experience and one-year follow-up. Cardiovasc. Intervent Radiol. 2010, 33:552-559.
6. Bot A., van Amerongen I.A., Groot R.D., Hoekstra N.L., Agterof W.G.M. Large deformation rheology of gelatin gels original research article. Polymer Gels Netw. 1996, 4:189-227.
7. Derdeyn C.P., Graves V.B., Salamat M.S., Rappe A. Collagen-coated acrylic microspheres for embolotherapy: in vivo and in vitro characteristics. Am. J. Neuroradiol. 1997, 18:647-653.
8. Derdeyn C.P., Moran C.J., Cross D.T., Dietrich H.H., Dacey R.G. Polyvinyl alcohol particle size and suspension characteristics. Am. J. Neuroradiol. 1995, 16:1335-1343.
9. Ding P., Norton I.T., Zhang Z., Pacek A.W. Mechanical properties of gelatin-rich micro-particles. J. Food Eng. 2008, 86:307-314.
10. Fopuz F., Okay O. Macroporous hydrogel beads of high toughness and superfast responsivity. Reactive Funct. Polymers 2009, 69:273-280.
11. Fung YC. Biomechanics, Mechanical Properties of Living Tissues 1993, Springer-Verlag.
12. Hertz H. Ueber die Berührung fester elastischer Körper. J. Die Reine und Angewandte Math. 1882, 92:156-171.
13. Hidaka K., Nakamura M., Osuga K., Miyazaki H., Wada S. Elastic characteristics of microspherical embolic agents used for vascular interventional radiology. J. Mech. Behav. Biomed. Mater. 2010, 7:497-503.
14. Jayakrishnan A., Thanoo B.C., Rathinam K., Ravimandalam K., Rao V.R.K., Lal A.V., Mohanty Mira Hydrogel microspheres from crosslinked poly(methyl methacrylate): synthesis and biocompatibility studies. Bull. Mater. Sci. 1989, 12(1):17-25. 10.1007/BF02744590.
15. Knaebel A., Rebre S.R., Lequeux F. Determination of the elastic modulus of the superabsorbent gel beads. Polymer Gels Netw. 1997, 5:107-121.
16. Kroencke T.J., Scheurig C., Lampmann L.E., Boekkooi P.F., Kissner L., Kluner C., Weichert W., Hamm B., Lohle P.N. Acrylamido polyvinyl alcohol microspheres for uterine artery embolization: 12-month clinical and MR imaging results. J. Vasc. Interv. Radiol. 2008, 19:47-57.
17. Laurent A. Microspheres and nonspherical particles for emboliza-tion. Tech. Vasc. Interv. Radiolo. 2007, 10:248-256.
18. Laurent A., Beaujeux R., Wassef M., Rüfenacht D., Boschetti E., Merland J.J. Tris acryl gelatin microspheres for therapeutic embolization, I: development and in vitro evaluation. Am. J. Neuroradiol. 1996, 17:533-540.
19. Laurent A., Velzenberger E., Wassef M., Pelage J.P., Lewis A.L. Do microspheres with narrow or standard size distributions localize differently in vasculature? An experimental study in sheep kidney and uterus. J. Vasc. Interv. Radiol. 2008, 19:1733-1739.
20. Laurent A., Wassef M., Chapot R., Houdart E., Merland J.J. Location of vessel occlusion of calibrated tris-acryl gelatin microspheres for tumor and arteriovenous malformation embolization. J. Vasc. Interv. Radiol. 2004, 15:491-496.
21. Laurent A., Wassef M., Chapot R., Wang Y., Houdart E., Feng L., Tran B.H.P., Merland J.J. Partition of calibrated tris-acryl gelatin microspheres in the arterial vasculature of embolized nasopharyngeal angiofibromas and paragangliomas. J. Vasc. Interv. Radiol. 2005, 16:507-513.
22. Laurent A., Wassef M., Namur J., Ghegediban H., Pelage J.P. Arterial distribution of calibrated tris-acryl gelatin and polyvinyl alcohol embolization microspheres in sheep uterus. Cardiovasc. Intervent Radiol. 2010, 33:995-1000.
23. Laurent A., Wassef M., Saint Maurice J.P., Namur J., Pelage J.P., Se-ron A., Chapot R., Merland J.J. Arterial distribution of calibrated tris-acryl gelatin and polyvinyl alcohol microspheres in a sheep kidney model. Invest. Radiol. 2006, 41:8-14.
24. Lewis A.L., Adams C., Busby W., Jones S.A., Wolfenden L.C., Lep-pard S.W., Palmer R.R., Small S. Comparative in vitro evaluation of mi-crospherical embolisation agents. J. Mater. Sci. Mater. Med. 2006, 17:1193-1204.
25. Lewis A.L., Taylor R.R., Hall B., Gonzalez M.V., Willis S.L., Stratford P.W. Pharmacokinetic and safety study of doxorubicin-eluting beads in a porcine model of hepatic arterial embolization. J. Vasc. Interv. Radiol. 2006, 17:1335-1343.
26. Liu K.K., Williams D.R., Briscoe B.J. The large deformation of a single micro-elastomeric sphere. J. Phys. D. Appl. Phys. 1998, 31:294-303.
27. Malagari K., Pomoni M., Kelekis A., Pomoni A., Dourakis S., Spyridopoulos T., Moschouris H., Emmanouil E., Rizos S., Kelekis D. Prospective randomized comparison of chemoembolization with doxorubicin-eluting beads and bland embolization with BeadBlock for hepatocellular carcinoma. Cardiovasc. Intervent Radiol. 2010, 33:541-551.
28. McEvoy H., Ross-Murphy S.B., Clark A.H. Large deformation and ultimate properties of biopolymer gels: 2 mixed gel systems. Polymer 1985, 26:1493-1500.
29. Nguyen V.B., Wang C.X., Thomas C.R., Zhang Z. Mechanical properties of single alginate microspheres determined by microcompression and finite element modeling. Chem. Eng. Sci. 2009, 64:821-829.
30. Pan Y., Xiong D. Stress relaxation behavior of nano-hydroxyapatite reinforced poly(vinyl alcohol) gel composites as biomaterial. J. Mater. Sci. 2010, 45:5495-5501.
31. Pelage J.P., Laurent A., Wassef M., Bonneau M., Germain D., Rymer R., Flaud P., Martal J., Merland J.J. Uterine artery embolization in sheep: comparison of acute effects with polyvinyl alcohol particles and calibrated microspheres. Radiology 2002, 224:436-445.
32. Raz N., Li J.K., Fiddes L.K., Tumarkin E., Walker G.C., Kumacheva E. Microgels with an interpenetrating network structure as a model system for cell studies. Macromolecules 2010, 43:7277-7281.
33. Saha D., Bhattacharya S. Characteristics of gellan gumbased food gels. J. Texture Studies 2010, 41:459-471.
34. Seron, A., Pelage, J.P., Counord, J.L., Guiffant, G., Laurent, A., 2005. Rigidity and elasticity of embosphere, bead block and contour SE microspheres. CIRSE (abstr) 89-179.
35. Sheng Y., Briscoe B.J., Maung R., Rovea C. Compression of polymer bound alumina agglomerates at the micro deformation scale. Powder Technol. 2004, 140:228-239.
36. Stampfl S., Bellemann N., Stampfl U., Sommer C.M., Thierjung H., Lopez-Benitez R., Radeleff B., Berger I., Richter G.M. Arterial distribution characteristics of Embozene particles and comparison with other spherical embolic agents in the porcine acute embolization model. J. Vasc. Interv. Radiol. 2009, 20:1597-1607.
37. Verret V., Ghegediban S.H., Wassef M., Pelage J.P., Golzarian J., Laurent A. The arterial distribution of embozene and embosphere microspheres in sheep kidney and uterus embolization models. J. Vasc. Interv. Radiol. 2011, 22:220-228.
38. Wang C.X., Cowen C., Zhang Z., Thomas C.R. High-speed compression of single alginate microspheres. Chem. Eng. Sci. 2005, 60:6649-6657.
39. Yan Y., Zhang Z., Stokes J.R., Zhou Q.Z., Ma G.H., Adams M.J. Mechanical characterization of agarose micro-particles with a narrow size distribution. Powder Technol. 2009, 192:122-130.
40. Zhang Z.L., Kristiansen H., Liu J. A method for determining elastic properties of micron-sized polymer particles by using flat punch test. Comput. Mater. Sci. 2007, 39:305-314.