Electrospray tandem mass spectrometry of poly(amino)ester dendrimers: Dissociation rules and structural characterization of defective molecules

International Journal of Mass Spectrometry

Volumn 308, Issue 1, 2011, Pages 56-64

  Tintaru, Aura ^a   Chendo, Christophe ^a   Monnier, Valérie ^a   Bouillon, Camille ^b   Quéléver, Gilles ^b   Peng, Ling ^b   Charles, Laurence ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

CID; Defective molecules; Dendrimers; Poly(amino)ester; Structural characterization

Indexed keywords

EID: 81155161881     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2011.07.021     Document Type: Article

References (17)

1. D.A. Tomalia, A.M. Naylor, and W.A. Goddard Starburst dendrimers - molecular-level control of size, shape, surface-chemistry, topology, and flexibility from atoms to macroscopic matter Angew. Chem. Int. Ed. 29 1990 138 175 (Pubitemid 20142204)
2. O.L.P. De Jesus, H.R. Ihre, L. Gagne, J.M.J. Frechet, and F.C. Szoka Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation Bioconjug. Chem. 13 2002 453 461 (Pubitemid 34535938)
3. H.R. Ihre, O.L.P. De Jesus, F.C. Szoka, and J.M.J. Frechet Polyester dendritic systems for drug delivery applications: design, synthesis, and characterization Bioconjug. Chem. 13 2002 443 452 (Pubitemid 34527506)
4. B. Buschhaus, F. Hampel, S. Grimme, and A. Hirsch Metal-induced chiral folding of depsipeptide dendrimers Chem. Eur. J. 11 2005 3530 3540 (Pubitemid 40819437)
5. C. Bouillon, G. Quelever, and L. Peng Efficient synthesis of esters containing tertiary amine functionalities via active cyanomethyl ester intermediates Tetrahedron Lett. 50 2009 4346 4349
6. C. Bouillon, A. Tintaru, V. Monnier, L. Charles, G. Quelever, and L. Peng Synthesis of poly(amino)ester dendrimers via active cyanomethyl ester intermediates J. Org. Chem. 75 2010 8685 8688
7. A. Tintaru, V. Monnier, C. Bouillon, R. Giordanengo, G. Quelever, L. Peng, and L. Charles Structural characterization of poly(amino)ester dendrimers and related impurities by electrospray tandem mass spectrometry Rapid Commun. Mass Spectrom. 24 2010 2207 2216
8. J.W. Weener, J.L.J. van Dongen, and E.W. Meijer Electrospray mass spectrometry studies of poly(propylene imine) dendrimers: probing reactivity in the gas phase J. Am. Chem. Soc. 121 1999 10346 10355 (Pubitemid 129541207)
9. S.A. McLuckey, K.G. Asano, T.G. Schaaff, and J.L. Stephenson Ion trap collisional activation of protonated poly(propylene imine) dendrimers: generations 1-5 Int. J. Mass Spectrom. 195 2000 419 437
10. A. Adhiya, and C. Wesdemiotis Poly(propylene imine) dendrimer conformations in the gas phase: a tandem mass spectrometry study Int. J. Mass Spectrom. 214 2002 75 88
11. M. He, and S.A. McLuckey Tandem mass spectrometry of half-generation PAMAM dendrimer anions Rapid Commun. Mass Spectrom. 18 2004 960 972 (Pubitemid 38619546)
12. C.L. Mazzitelli, and J.S. Brodbelt Investigation of silver binding to polyamidoamine (PAMAM) dendrimers by ESI tandem mass spectrometry J. Am. Soc. Mass Spectrom. 17 2006 676 684
13. R. Giordanengo, M. Mazarin, J.Y. Wu, L. Peng, and L. Charles Propagation of structural deviations of poly (amidoamine) fan-shape dendrimers (generations 0-3) characterized by MALDI and electrospray mass spectrometry Int. J. Mass Spectrom. 266 2007 62 75
14. J. Subbi, R. Aguraiuja, R. Tanner, V. Allikmaa, and M. Lopp Fragmentation of poly(amidoamine) dendrimers in matrix-assisted laser desorption Eur. Polym. J. 41 2005 2552 2558 (Pubitemid 41261568)
15. L. Charles Influence of internal standard charge state on the accuracy of mass measurements in orthogonal acceleration time-of-flight mass spectrometers Rapid Commun. Mass Spectrom. 22 2008 151 155 (Pubitemid 351156127)
16. K. Chaicharoen, M.J. Polce, A. Singh, C. Pugh, and C. Wesdemiotis Characterization of linear and branched polyacrylates by tandem mass spectrometry Anal. Bioanal. Chem. 392 2008 595 607
17. T. Trimaille, K. Mabrouk, V. Monnier, L. Charles, D. Bertin, and D. Gigmes SG1-functionalized peptides as precursors for polymer-peptide conjugates: a straightforward approach Macromolecules 43 2010 4864 4870